Results 241 to 250 of about 1,846,216 (386)

The Antisense Protein ASP of HIV-1 Enhances Viral Entry in CD4+ T Cells. [PDF]

Viruses
Houmey MA, Caico I, Rivault A, Espert L, Mesnard JM, Romerio F, Chazal N.   +6 more
europepmc   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry. [PDF]

Commun Biol
Ortiz-Mateu J, Belda D, Avilés-Alía AI, Alonso-Romero J, García-Murria MJ, Mingarro I, Geller R, Martinez-Gil L.   +7 more
europepmc   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Garlic-Derived Phytochemical Candidates Predicted to Disrupt SARS-CoV-2 RBD-ACE2 Binding and Inhibit Viral Entry. [PDF]

Molecules
García-Delgado MS, Herrera-Rodulfo AF, Reyes-Melo KY, Mohan A, Góngora-Rivera F, Pedroza-Flores JA, Paz-González AD, Rivera G, Camacho-Corona MDR, Carrillo-Tripp M.   +9 more
europepmc   +1 more source

Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo

, 2022
Adrian Najer, Joshua Blight, Catherine Ducker, Matteo Gasbarri, Jonathan C. Brown, Junyi Che, Håkon Høgset, Catherine Saunders, Miina Ojansivu, Zixuan Lu, Yiyang Lin, Jonathan Yeow, Omar Rifaie‐Graham, Michael Potter, Renée L. Tonkin, Jelle Penders, James Doutch, Athina Georgiadou, Hanna M. G. Barriga, Margaret N. Holme, Aubrey J. Cunnington, Laurence Bugeon, Margaret J. Dallman, William Barclay, Francesco Stellacci, Jake Baum, Molly M. Stevens   +26 more
openalex   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replication. [PDF]

mBio
Feng F, Chen J, Li R, Zhu Y, Ma Y, Wang Z, Wang Y, Gao Z, Yang L, Yu Y, Liu Y, Sun Y, Liao Y, Huang X, Zhang Q, Huang Y, Qiu L, Wu J, Zhao J, Liu C, Ding Q, Xie Y, Yuan Z, Hong Y, Zhang P, Sun J, Zhao J, Zhang R.   +27 more
europepmc   +1 more source

Fibronectin : role in viral cell association, fusion and entry of influenza A virus

, 2012
Horasis Leung Sze-Yui
openalex   +1 more source

Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein

, 2020
Yinyi Gao, Han Cheng, Sameer Ullah Khan, Gaokeng Xiao, Lijun Rong, Chuan Bai   +5 more
openalex   +2 more sources