Results 261 to 270 of about 2,147,758 (302)
Some of the next articles are maybe not open access.
Tight Junctions and Viral Entry
Future Virology, 2010A wide variety of different viruses use tight junction (TJ) proteins in the course of infection and different mechanisms of pathogen–TJ interactions have been described; pathogens may induce the reorganization or degradation of distinct TJ proteins, reorganization of the cell cytoskeleton, activation of host-cell signaling pathways and/or use TJ ...
ZEISEL M.B., TUREK M., BAUMERT T.F.
openaire +1 more source
Common Principles in Viral Entry
Annual Review of Microbiology, 2002▪ Abstract Viruses occur throughout the biosphere. Cells of Eukarya, Bacteria, and Archaea are infected by a variety of viruses that considerably outnumber the host cells. Although viruses have adapted to different host systems during evolution and many different viral strategies have developed, certain similarities can be found.
Minna M, Poranen +2 more
openaire +2 more sources
2015
Epstein-Barr virus primarily, though not exclusively, infects B cells and epithelial cells. Many of the virus and cell proteins that are involved in entry into these two cell types in vitro have been identified, and their roles in attachment and fusion are being explored.
Liudmila S, Chesnokova +2 more
openaire +2 more sources
Epstein-Barr virus primarily, though not exclusively, infects B cells and epithelial cells. Many of the virus and cell proteins that are involved in entry into these two cell types in vitro have been identified, and their roles in attachment and fusion are being explored.
Liudmila S, Chesnokova +2 more
openaire +2 more sources
2008
The entry of viruses into target cells involves a complex series of sequential steps, with opportunities for inhibition at every stage. Entry inhibitors exert their biological properties by inhibiting protein-protein interactions either within the viral envelope (Env) glycoproteins or between viral Env and host-cell receptors.
Tom, Melby, Mike, Westby
openaire +2 more sources
The entry of viruses into target cells involves a complex series of sequential steps, with opportunities for inhibition at every stage. Entry inhibitors exert their biological properties by inhibiting protein-protein interactions either within the viral envelope (Env) glycoproteins or between viral Env and host-cell receptors.
Tom, Melby, Mike, Westby
openaire +2 more sources
AIP Conference Proceedings, 2010
Successful viral infection of a healthy cell requires complex host‐pathogen interactions. In this talk we focus on the dynamics specific to the HIV virus entering a eucaryotic cell. We model viral entry as a stochastic engagement of receptors and coreceptors on the cell surface.
Maria R. D’Orsogna +3 more
openaire +1 more source
Successful viral infection of a healthy cell requires complex host‐pathogen interactions. In this talk we focus on the dynamics specific to the HIV virus entering a eucaryotic cell. We model viral entry as a stochastic engagement of receptors and coreceptors on the cell surface.
Maria R. D’Orsogna +3 more
openaire +1 more source
Role of Protein–Lipid Interactions in Viral Entry
Advanced Biology, 2022AbstractThe viral entry consists of several sequential events that ensure the attachment of the virus to the host cell and the introduction of its genetic material for the continuation of the replication cycle. Both cellular and viral lipids have gained a wider focus in recent years in the field of viral entry, as they are found to play key roles in ...
Jon Ander Nieto‐Garai +3 more
openaire +3 more sources
New England Journal of Medicine, 2004
Until recently, antiviral drugs were both uncommon and not terribly potent. This has changed: during the past decade, more than 30 antiviral drugs have been licensed, and many of them are very effe...
openaire +2 more sources
Until recently, antiviral drugs were both uncommon and not terribly potent. This has changed: during the past decade, more than 30 antiviral drugs have been licensed, and many of them are very effe...
openaire +2 more sources
Epstein-Barr virus chiefly infects B cells and epithelial cells but is capable of infecting other cell types in the human host. Host cell entry is a complex process mediated by several viral glycoproteins that define tropism and mediate membrane fusion.
Samantha, Hardy +3 more
openaire +2 more sources
Samantha, Hardy +3 more
openaire +2 more sources
An Enzymatic Assay for Detection of Viral Entry
Current Protocols in Cell Biology, 2011AbstractThis unit describes a viral entry assay where a beta‐lactamase reporter protein fused to the matrix protein of either influenza (BlaM1) or ebola virus (BlaVP40) is packaged as a structural component into virus‐like particles (VLPs). The Bla reporter is released upon fusion with target cells and can be detected in live cells by flow cytometry ...
Donna M, Tscherne +1 more
openaire +2 more sources
HIV-Resistance to Viral Entry Inhibitors
Current Pharmaceutical Design, 2004An increasing number of human immunodeficiency virus (HIV)-infected patients have detectable viraemia despite treatment with multiple-drug combinations or have developed resistance to all available classes of antiretroviral therapy. HIV entry has become an important pharmacological target. Enfuvirtide is the first HIV entry inhibitor to be approved for
Luis, Menéndez-Arias, José A, Esté
openaire +2 more sources