Results 271 to 280 of about 488,522 (303)
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Epstein-Barr virus chiefly infects B cells and epithelial cells but is capable of infecting other cell types in the human host. Host cell entry is a complex process mediated by several viral glycoproteins that define tropism and mediate membrane fusion.
Samantha, Hardy +3 more
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Samantha, Hardy +3 more
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Henipavirus Membrane Fusion and Viral Entry
2012Nipah (NiV) and Hendra (HeV) viruses cause cell-cell fusion (syncytia) in brain, lung, heart, and kidney tissues, leading to encephalitis, pneumonia, and often death. Membrane fusion is essential to both viral entry and virus-induced cell-cell fusion, a hallmark of henipavirus infections.
Hector C, Aguilar, Ronald M, Iorio
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HIV-1 cell entry and advances in viral entry inhibitor therapy
Journal of Clinical Virology, 2003Despite the considerable successes of highly active antiretroviral therapy, new classes of therapeutic agents are still urgently needed. Unfortunately, the emergence of antiviral resistance and drug toxicity remain challenging obstacles to successful treatment in many HIV-1-infected individuals. HIV-1 entry is a multi-step process that is an attractive
Louise A, Cooley, Sharon R, Lewin
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Science Signaling, 2012
The receptor EphrinA2 promotes herpesvirus entry into endothelial cells.
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The receptor EphrinA2 promotes herpesvirus entry into endothelial cells.
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Nonenveloped Capsid: Mechanisms of Viral Entry
Future Virology, 2014ABSTRACT  Viruses are a diverse class of nanoparticles. However, they have evolved a few common mechanisms that enable successful infection of their host cells. The first stage of this process involves entry into the cell. For enveloped viruses this process has been well characterized.
Bridget Lins, Mavis Agbandje-McKenna
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2013
Attachment Factors.- Picornavirus Entry.- Reovirus Receptors, Cell Entry, and Proapoptotic Signaling.- Entry of Influenza Virus.- Filovirus Entry.- Paramyxovirus Entry.- Cellular entry of retroviruses.- Class II Fusion Proteins.- Entry of Rhabdoviruses into Animal Cells.- Entry of Herpesviruses into Cells: The Enigma Variations.
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Attachment Factors.- Picornavirus Entry.- Reovirus Receptors, Cell Entry, and Proapoptotic Signaling.- Entry of Influenza Virus.- Filovirus Entry.- Paramyxovirus Entry.- Cellular entry of retroviruses.- Class II Fusion Proteins.- Entry of Rhabdoviruses into Animal Cells.- Entry of Herpesviruses into Cells: The Enigma Variations.
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Neutralizing antibodies to block viral entry and for identification of entry inhibitors
Antiviral ResearchNeutralizing antibodies (NAbs) are naturally produced by our immune system to combat viral infections. Clinically, neutralizing antibodies with potent efficacy and high specificity have been extensively used to prevent and treat a wide variety of viral infections, including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Human ...
Ee Hong Tam +4 more
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Viral and host heterogeneity and their effects on the viral life cycle
Nature Reviews Microbiology, 2020Jennifer E Jones, Valerie Le Sage
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The structural basis of herpesvirus entry
Nature Reviews Microbiology, 2020Sarah A Connolly +2 more
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A molecular understanding of alphavirus entry and antibody protection
Nature Reviews Microbiology, 2022Arthur S Kim, Michael Diamond
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