Results 51 to 60 of about 2,207,666 (298)

Antibody-Dependent Dengue Virus Entry Modulates Cell Intrinsic Responses for Enhanced Infection

mSphere, 2019
Dengue is caused by infection with any one of four dengue viruses (DENV); the risk of severe disease appears to be enhanced by the cross-reactive or subneutralizing levels of antibody from a prior DENV infection.
Candice Y. Y. Chan, John Zhong Heng Low, Esther Shuyi Gan, Eugenia Ziying Ong, Summer Li-Xin Zhang, Hwee Cheng Tan, Xiaoran Chai, Sujoy Ghosh, Eng Eong Ooi, Kuan Rong Chan   +9 more
doaj   +1 more source

The Role of L-Selectin in HIV Infection

Frontiers in Microbiology, 2021
HIV envelope glycoprotein is the most heavily glycosylated viral protein complex identified with over 20 glycans on its surface. This glycan canopy is thought to primarily shield the virus from host immune recognition as glycans are poor immunogens in ...
Jason Segura, Biao He, Joanna Ireland, Zhongcheng Zou, Thomas Shen, Gwynne Roth, Peter D. Sun   +6 more
doaj   +1 more source

Sensitivity of envelope glycoproteins to viral entry inhibitors.

, 2019
Sensitivity of envelope glycoproteins to viral entry inhibitors.
Megan Files (1523566), Kristin M. Bedard (6112208), Sean M. Amberg (6112211), Amy L. Moore (6112205), Brian B. Gowen (37270), Kevin F. Jones (346136), Kie-Hoon Jung (241704), Marcus J. Korth (259509), James R. Burgeson (2725450), Ikenna G. Madu (6112202), Shanthakumar R. Tyavanagimatt (346123), Dongcheng Dai (2497414), Dima N. Gharaibeh (1585096), Shawn P. Iadonato (4258879)   +13 more
core   +1 more source

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity [PDF]

, 2011
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...
Paul Klenerman, Malte Heeg, John, Mina, James, Ian, Ulsenheimer, Axel, Helmut M. Diepolder, Lucas, A.D., Silvana Gaudieri, Ian James, John, M., Andri Rauch, Klenerman, P., Simon Mallal, Heeg, Malte, Mallal, Simon, Lucas, Andrew, Nolan, D., Lucas, M., Heeg, M., Michaela Lucas, Diepolder, H.M., Mallal, S., Gaudieri, S., Nolan, David, David Nolan, Klenerman, Paul, Diepolder, Helmut M., Pfafferott, K., Rauch, A., Ulsenheimer, A., Pfafferott, Katja, Lucas, Michaela, Katja Pfafferott, Andrew Lucas, Rauch, Andri, Diepolder, Helmut M, Axel Ulsenheimer, Mina John, Helmut M Diepolder, James, I., Gaudieri, Silvana, Lucas Andrew, Mallal Simon, Diepolder Helmut M., Pfafferott Katja, Gaudieri Silvana, John Mina, Klenerman Paul, Ulsenheimer Axel, Lucas Michaela, Nolan David, Rauch Andri, James Ian, Heeg Malte   +53 more
core   +3 more sources

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Analysis of the Subunit Stoichiometries in Viral Entry

PLoS ONE, 2012
PLoS ONE, 7 (3)
Magnus C, Regoes RR
openaire   +7 more sources

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Evidence for Paralichthys olivaceus IFITM1 antiviral effect by impeding viral entry into target cells

, 2013
Interferon-inducible transmembrane (IFITM) protein family is novel viral restriction factors with representative transmembrane structure. These proteins also exist in fish, however, their roles in the innate immune response remain unknown.
Zhu, Rong, Gui, Jian-Fang, Zhang, Qi-Ya, Wang, Jun, Lei, Xiao-Ying, Zhang, QY (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Donghu South Rd 7, Wuhan 430072, Peoples R China.   +5 more
core   +1 more source

A capsid-encoded PPxY-motif facilitates adenovirus entry. [PDF]

, 2010
Viruses use cellular machinery to enter and infect cells. In this study we address the cell entry mechanisms of nonenveloped adenoviruses (Ads). We show that protein VI, an internal capsid protein, is rapidly exposed after cell surface attachment and ...
Segura-Morales, Carolina, Ruzsics, Zsolt, Kremer, Eric J, Wiethoff, Christopher M, Kremer Eric J., Baptist Jammart, Wodrich, Harald, Jammart, Baptist, Seelmeir Sigrid, Jammart Baptist, Christopher M Wiethoff, Wiethoff, Christopher M., Ruzsics Zsolt, Segura-Morales Carolina, Seelmeir, Sigrid, Carolina Segura-Morales, Henaff, Daniel, Zsolt Ruzsics, Kremer, Eric J., Coux, Olivier, Harald Wodrich, Henaff Daniel, Sigrid Seelmeir, Coux Olivier, Wodrich Harald, Eric J Kremer, Daniel Henaff, Olivier Coux, Wiethoff Christopher M.   +28 more
core   +1 more source

LRRC15 inhibits SARS-CoV-2 cellular entry in trans.

PLoS Biology, 2022
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is mediated by the entry receptor angiotensin-converting enzyme 2 (ACE2). Although attachment factors and coreceptors facilitating entry are extensively studied, cellular entry ...
Jaewon Song, Ryan D Chow, Mario A Peña-Hernández, Li Zhang, Skylar A Loeb, Eui-Young So, Olin D Liang, Ping Ren, Sidi Chen, Craig B Wilen, Sanghyun Lee   +10 more
doaj   +1 more source