Results 61 to 70 of about 2,207,666 (298)

The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells [PDF]

, 2009
Herpes Simplex Virus (HSV) – 1 also known as Human Herpes Virus (HHV) – 1 is a common infectious agent of humans which can cause a wide variety of clinical outcomes, ranging from mild mucocutaneous lesions to long term morbidity and possible mortality.
Reske, A., Reske, A
core  

Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]

, 2009
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr, Ulrich Koszinowski, Mühlbach, Hermine, Koszinowski, Ulrich H., Zsolt Ruzsics, Christian Mohr, Mohr, Christian A., Ruzsics, Zsolt, Hermine Mühlbach, Ulrich H. Koszinowski   +9 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Simulation results for different viral entry points.

, 2015
Simulation results of cellular space fraction, Sc, for DSP and tongue over a 48 hour timescale for maximal replication rate, ξ, and rate of FMDV resource consumption, ρ, both set at 0.29 × their default estimates.
Kyriaki Giorgakoudi (802788), Simon Gubbins (63360), David Schley (332381), John Ward (332385), Nicholas Juleff (270855), Zhidong Zhang (270864)   +5 more
core   +1 more source

Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection. [PDF]

, 2012
During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging) to dissect the real ...
Lisa Marcinowski, Martina Rieder, Caroline C. Friedel (7812728), Marcinowski, Lisa, Lars Dölken, de Graaf, Miranda, Thomas Bonfert, Caroline C. Friedel (29226), Lars Dölken (138985), Györy, Ildiko, Caroline C Friedel, Philip Rosenstiel (68103), Jens B Bosse, Ruzsics, Zsolt, Ralf Zimmer, Bosse, Jens B., Lukas Windhager, Rosenstiel, Philip, Zsolt Ruzsics (75383), Jens B. Bosse (7812725), Zimmer, Ralf, Thomas Bonfert (138970), Rieder, Martina, Lisa Marcinowski (138962), Jens B. Bosse (138966), Friedel, Caroline C., Ildiko Györy (138972), Michael Lidschreiber, Ildiko Györy, Bernd Rädle (138968), Zsolt Ruzsics, Ralf Zimmer (21157), Windhager, Lukas, Miranda de Graaf, Philip Rosenstiel, Michael Lidschreiber (138963), Dölken, Lars, Olivia Prazeres da Costa, Prazeres da Costa, Olivia, Olivia Prazeres da Costa (138979), Bernd Rädle, Lukas Windhager (138964), Lidschreiber, Michael, Miranda de Graaf (138976), Bonfert, Thomas, Rädle, Bernd, Martina Rieder (138965), de Graaf Miranda, Györy Ildiko, Bosse Jens B., da Costa Olivia Prazeres, Marcinowski, L;Lidschreiber, M;Windhager, L;Rieder, M;Bosse, JB;Rädle, B;Bonfert, T;Györy, I;de Graaf, M;Prazeres da Costa, O;Rosenstiel, P;Friedel, CC;Zimmer, R;Ruzsics, Z;Dölken, L, Windhager Lukas, Dölken Lars, Rosenstiel Philip, Marcinowski Lisa, Bonfert Thomas, Zimmer Ralf, Ruzsics Zsolt, Rieder Martina, Friedel Caroline C., Rädle Bernd, Lidschreiber Michael   +62 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

CD81 is a receptor for equine arteritis virus (family: Arteriviridae)

mBio
Arteriviruses are a family of single-stranded, positive-sense RNA (+ssRNA) viruses that infect diverse animal hosts. Many arteriviruses are macrophage-tropic, consistent with their utilization of the macrophage-specific molecule CD163 as a receptor ...
Sara M. Maloney, Teressa M. Shaw, Kylie M. Nennig, Malorie S. Larsen, Aadit Shah, Ashish Kumar, Joseph Marcotrigiano, Joe Grove, Eric J. Snijder, Robert N. Kirchdoerfer, Adam L. Bailey   +10 more
doaj   +1 more source

Quantitative membrane proteomics reveals a role for tetraspanin enriched microdomains during entry of human cytomegalovirus. [PDF]

PLoS ONE, 2017
Human cytomegalovirus (HCMV) depends on and modulates multiple host cell membrane proteins during each stage of the viral life cycle. To gain a global view of the impact of HCMV-infection on membrane proteins, we analyzed HCMV-induced changes in the ...
Kasinath Viswanathan, Marieke C Verweij, Nessy John, Daniel Malouli, Klaus Früh   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source