Results 61 to 70 of about 484,497 (156)
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
, 2020 Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
core +1 more source
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
, 2009 Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
core +2 more sources
npj VaccinesBooster vaccinations are recommended to improve protection against severe disease from SARS-CoV-2 infection. With primary vaccinations involving various adenoviral vector and mRNA-based formulations, it remains unclear if these differentially affect the ...
Gemma E. Hartley +9 more
doaj +1 more source
CD81 is a receptor for equine arteritis virus (family: Arteriviridae)
mBioArteriviruses are a family of single-stranded, positive-sense RNA (+ssRNA) viruses that infect diverse animal hosts. Many arteriviruses are macrophage-tropic, consistent with their utilization of the macrophage-specific molecule CD163 as a receptor ...
Sara M. Maloney +10 more
doaj +1 more source
npj VirusesHIV-1 envelope glycoproteins (Envs) mediate viral entry and are sole target of neutralizing antibodies. Thus, HIV-1 Envs must maintain a delicate balance between evading neutralizing antibodies while still preserving viral compatibility to mediate entry ...
Durgadevi Parthasarathy +7 more
doaj +1 more source
Envelope-receptor interactions in Nipah virus pathobiology. [PDF]
, 2007 Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core +1 more source
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation [PDF]
, 2015 Macrophages are key targets of HIV-1 infection. We have previously described that the expressionof CC chemokine ligand 2 (CCL2) increases during monocyte differentiation to macrophages and it is furtherup-modulated by HIV-1 exposure.
Andreotti, Mauro +15 more
core +3 more sources
BST2/Tetherin enhances entry of human cytomegalovirus.
PLoS Pathogens, 2011 Interferon-induced BST2/Tetherin prevents budding of vpu-deficient HIV-1 by tethering mature viral particles to the plasma membrane. BST2 also inhibits release of other enveloped viruses including Ebola virus and Kaposi's sarcoma associated herpesvirus ...
Kasinath Viswanathan +5 more
doaj +1 more source
Allergens, germs and asthma [PDF]
, 2015 Objective To explore asthma pathogenesis using data from upper and lower airways. Data Source English-language papers on human asthma and nasal polyp subjects from 1990 onwards.
Scadding, GK
core
Norovirus Attachment and Entry
Viruses, 2019 Human norovirus is a major human pathogen causing the majority of cases of viral gastroenteritis globally. Viral entry is the first step of the viral life cycle and is a significant determinant of cell tropism, host range, immune interactions, and ...
Vincent R. Graziano +2 more
doaj +1 more source