Results 71 to 80 of about 1,846,216 (386)

Antibody-Dependent Dengue Virus Entry Modulates Cell Intrinsic Responses for Enhanced Infection

open access: yesmSphere, 2019
Dengue is caused by infection with any one of four dengue viruses (DENV); the risk of severe disease appears to be enhanced by the cross-reactive or subneutralizing levels of antibody from a prior DENV infection.
Candice Y. Y. Chan   +9 more
doaj   +1 more source

Measuring the force ejecting DNA from phage [PDF]

open access: yes, 2004
We discuss how a balance can be established between the force acting to eject DNA from viral capsids and the force resisting its entry into a colloidal suspension which mimics the host cell cytoplasm.
Castelnovo, M.   +3 more
core   +1 more source

Anatomy of a viral entry platform differentially functionalized by integrins α3 and α6

open access: yesScientific Reports, 2020
During cell invasion, human papillomaviruses use large CD151 patches on the cell surface. Here, we studied whether these patches are defined architectures with features for virus binding and/or internalization.
Jérôme Finke   +5 more
semanticscholar   +1 more source

LRRC15 inhibits SARS-CoV-2 cellular entry in trans.

open access: yesPLoS Biology, 2022
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is mediated by the entry receptor angiotensin-converting enzyme 2 (ACE2). Although attachment factors and coreceptors facilitating entry are extensively studied, cellular entry ...
Jaewon Song   +10 more
doaj   +1 more source

Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry [PDF]

open access: yes, 2012
Protein phosphorylation is a common post-translational modification in eukaryotic cells and has a wide range of functional effects. Here, we used mass spectrometry to search for phosphorylated residues in all the proteins of influenza A and B viruses ...
Denham, Eleanor M.   +8 more
core   +3 more sources

Engineering multiple levels of specificity in an RNA viral vector [PDF]

open access: yes, 2020
Synthetic molecular circuits could provide powerful therapeutic capabilities, but delivering them to specific cell types and controlling them remains challenging.
Chong, Lucy S.   +4 more
core   +1 more source

Role of Ezrin Phosphorylation in HIV-1 Replication

open access: yesFrontiers in Microbiology, 2018
Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release.
Haruka Kamiyama   +11 more
doaj   +1 more source

Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

open access: yesMicrobiology Spectrum, 2022
The SARS-CoV-2 coronavirus, which causes COVID-19, uses a viral surface spike protein for host cell entry and the human cell-surface transmembrane serine protease, TMPRSS2, to process the spike protein.
Yuri Kosinsky   +4 more
doaj   +1 more source

Signalling in viral entry

open access: yesCellular and Molecular Life Sciences CMLS, 2002
Viral infections are serious battles between pathogens and hosts. They can result in cell death, elimination of the virus or latent infection keeping both cells and pathogens alive. The outcome of an infection is often determined by cell signalling. Viruses deliver genomes and proteins with signalling potential into target cells and thereby alter the ...
openaire   +3 more sources

Viral entry, lipid rafts and caveosomes

open access: yesAnnals of Medicine, 2005
Lipid rafts and caveolae are detergent-insoluble plasma membrane microdomains, involved in cellular endocytic processes and signalling. Several viruses, including a human pathogen, echovirus 1, and an extensively studied simian virus 40 utilize these domains for internalization into the host cells.
Vilja M, Pietiäinen   +3 more
openaire   +2 more sources

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