Results 31 to 40 of about 203,793 (303)

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J., Engelsma, M.Y., Peeters, B.P.H., Rottier, P.J.M., van Beurden, S.J.   +4 more
core   +3 more sources

An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]

, 2020
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip, Daled, Simon, Dhaenens, Maarten, Laval, Kathlyn, Nauwynck, Hans, Pasmans, Frank, Poelaert, Katrien, Van Cleemput, Jolien, Vanderheijden, Nathalie   +8 more
core   +2 more sources

HSV-1 gM and the gK/pUL20 Complex Are Important for the Localization of gD and gH/L to Viral Assembly Sites

Viruses, 2015
Herpes simplex virus-1 (HSV-1), like all herpesviruses, is a large complex DNA virus containing up to 16 different viral membrane proteins in its envelope.
Sheung-Yee Kathy Lau, Colin M. Crump
doaj   +1 more source

NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway

Nature Communications, 2023
Autophagy receptor NDP52 triggers bacterial autophagy against infection. However, the ability of NDP52 to protect against viral infection has not been established.
Shuzhi Cui, Tian Xia, Jianjin Zhao, Xiaoyu Ren, Tingtao Wu, Mireille Kameni, Xiaoju Guo, Li He, Jingao Guo, Aléria Duperray-Susini, Florence Levillayer, Jean-Marc Collard, Jin Zhong, Lifeng Pan, Frédéric Tangy, Pierre-Olivier Vidalain, Dongming Zhou, Yaming Jiu, Mathias Faure, Yu Wei   +19 more
doaj   +1 more source

Influence of N-glycosylation on Expression and Function of Pseudorabies Virus Glycoprotein gB

Pathogens, 2021
Envelope glycoprotein (g)B is conserved throughout the Herpesviridae and mediates fusion of the viral envelope with cellular membranes for infectious entry and spread.
Melina Vallbracht, Barbara G. Klupp, Thomas C. Mettenleiter   +2 more
doaj   +1 more source

Visualization of membrane protein domains by cryo-electron microscopy of dengue virus [PDF]

, 2003
Improved technology for reconstructing cryo-electron microscopy (cryo-EM) images has now made it possible to determine secondary structural features of membrane proteins in enveloped viruses.
AJ Johnson, BD Lindenbach, BU Barth, CT Jones, DLD Caspar, DS Burke, DWC Beasley, EJ Mancini, FA Rey, FX Heinz, GW Smith, IC Lorenz, J Lescar, James H Strauss, Jeroen Corver, JH Strauss, JH Strauss, JJB Cockburn, JT Roehrig, K Stiasny, LJ McGuffin, MG Rossmann, MG Rossmann, Michael G Rossmann, ML Ng, N Grigorieff, Paul R Chipman, Peter R Johnson, PJL Werten, Richard J Kuhn, RJ Kuhn, S Bhardwaj, S Elshuber, S Lee, SL Allison, SL Allison, Suchetana Mukhopadhyay, T Solomon, Timothy S Baker, U Skoging, VM Unger, W Zhang, WD Crill, Wei Zhang, Y Ji, Y Modis, Y Zhang, Ying Zhang, YS Hahn   +48 more
core   +1 more source

Discovery of Immunologically Inspired Small Molecules That Target the Viral Envelope Protein [PDF]

ACS Infectious Diseases, 2018
Dengue virus is a major human pathogen that infects over 390 million people annually leading to approximately 500 000 hospitalizations due to severe dengue. Since the only marketed vaccine, Dengvaxia, has recently been shown to increase disease severity in those lacking natural immunity, antivirals to prevent or treat dengue  infection represent a ...
Wenlong Lian, Jaebong Jang, Supanee Potisopon, Pi-Chun Li, Amal Rahmeh, Jinhua Wang, Nicholas P. Kwiatkowski, Nathanael S. Gray, Priscilla L. Yang   +8 more
openaire   +2 more sources

Evidence that Gag facilitates HIV-1 envelope association both in GPI-enriched plasma membrane and detergent resistant membranes and facilitates envelope incorporation onto virions in primary CD4⁺ T cells

Virology Journal, 2010
HIV-1 particle assembly mediated by viral Gag protein occurs predominantly at plasma membrane. While colocalization of HIV-1 envelope with lipid rich microenvironment have been shown in T cells, the significance of viral proteins modulating envelope ...
Bhattacharya Jayanta, Gautam Archana, Patil Ajit   +2 more
doaj   +1 more source

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment [PDF]

Cell Reports, 2019
The mechanisms that regulate envelopment of HCV and other viruses that bud intracellularly and/or lack late-domain motifs are largely unknown. We reported that K63 polyubiquitination of the HCV nonstructural (NS) 2 protein mediates HRS (ESCRT-0 component) binding and envelopment.
Kumar, Sathish, Barouch-Bentov, Rina, Xiao, Fei, Schor, Stanford, Pu, Szuyuan, Biquand, Elise, Lu, Albert, Lindenbach, Brett, Jacob, Yves, Demeret, Caroline, Einav, Shirit   +10 more
openaire   +4 more sources

Epstein–Barr virus tegument protein BGLF2 in exosomes released from virus-producing cells facilitates de novo infection

Cell Communication and Signaling, 2022
Background Viruses must adapt to the environment of their host cells to establish infection and persist. Diverse mammalian cells, including virus-infected cells, release extracellular vesicles such as exosomes containing proteins and miRNAs, and use ...
Yoshitaka Sato, Masahiro Yaguchi, Yusuke Okuno, Hanako Ishimaru, Ken Sagou, Somi Ozaki, Takeshi Suzuki, Tomoki Inagaki, Miki Umeda, Takahiro Watanabe, Masahiro Fujimuro, Takayuki Murata, Hiroshi Kimura   +12 more
doaj   +1 more source