Results 11 to 20 of about 141,914 (260)
Structure and Role of O-Linked Glycans in Viral Envelope Proteins
Annual Review of Virology, 2023 N- and O-glycans are both important constituents of viral envelope glycoproteins. O-linked glycosylation can be initiated by any of 20 different human polypeptide O-acetylgalactosaminyl transferases, resulting in an important functional O-glycan heterogeneity.
Olofsson, Sigvard +3 more
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Yeast two hybrid analyses reveal novel binary interactions between human cytomegalovirus-encoded virion proteins. [PDF]
PLoS ONE, 2011 Human cytomegalovirus (HCMV) is the largest human herpesvirus and its virion contains many viral encoded proteins found in the capsid, tegument, and envelope.
Aaron To +6 more
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Cell type-specific delivery by modular envelope design
Nature Communications, 2023 The delivery of genetic cargo remains one of the largest obstacles to the successful translation of experimental therapies, in large part due to the absence of targetable delivery vectors.
Daniel Strebinger +5 more
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HIV-1 Envelope Glycoprotein at the Interface of Host Restriction and Virus Evasion
Viruses, 2019 Without viral envelope proteins, viruses cannot enter cells to start infection. As the major viral proteins present on the surface of virions, viral envelope proteins are a prominent target of the host immune system in preventing and ultimately ...
Saina Beitari +3 more
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Flavivirus Envelope Protein Glycosylation: Impacts on Viral Infection and Pathogenesis
Journal of Virology, 2020 Flaviviruses encode one, two, or no N -linked glycosylation sites on their envelope proteins. Glycosylation can impact virus interactions with cell surface attachment factors and also may impact virion stability and virus replication.
Derek L. Carbaugh, Helen M. Lazear
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Nucleocapsid-Independent Specific Viral RNA Packaging via Viral Envelope Protein and Viral RNA Signal [PDF]
Journal of Virology, 2003 ABSTRACT For any of the enveloped RNA viruses studied to date, recognition of a specific RNA packaging signal by the virus's nucleocapsid (N) protein is the first step described in the process of viral RNA packaging. In the murine coronavirus a selective interaction between the viral transmembrane envelope protein M and the viral
Narayanan, K +3 more
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Viruses, 2016 Interaction of viral envelope proteins with host cell membranes has been extensively investigated in a number of systems. However, the biological relevance of these interactions in vivo has been hampered by the absence of adequate animal models.
Alix de Brogniez, Jan Mast, Luc Willems
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Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein [PDF]
Cell Chemical Biology, 2018 Viral envelope proteins are required for productive viral entry and initiation of infection. Although the humoral immune system provides ample evidence for targeting envelope proteins as an antiviral strategy, there are few pharmacological interventions that have this mode of action.
Melissanne, de Wispelaere +15 more
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Fluorescence Microscopy of the HIV-1 Envelope
Viruses, 2020 Human immunodeficiency virus (HIV) infection constitutes a major health and social issue worldwide. HIV infects cells by fusing its envelope with the target cell plasma membrane.
Pablo Carravilla +2 more
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The key amino acids of E protein involved in early flavivirus infection: viral entry
Virology Journal, 2021 Flaviviruses are enveloped viruses that infect multiple hosts. Envelope proteins are the outermost proteins in the structure of flaviviruses and mediate viral infection.
Tao Hu +4 more
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