Results 11 to 20 of about 2,348,486 (249)

Cell type-specific delivery by modular envelope design

Nature Communications, 2023
The delivery of genetic cargo remains one of the largest obstacles to the successful translation of experimental therapies, in large part due to the absence of targetable delivery vectors.
Daniel Strebinger, Chris J. Frangieh, Mirco J. Friedrich, Guilhem Faure, Rhiannon K. Macrae, Feng Zhang   +5 more
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Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]

, 2013
The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Mike Heilemann, Barbara Müller, Walter Muranyi (212637), Malkusch, Sebastian, Müller, Barbara, Hans-Georg Kräusslich (7273), Walter Muranyi, Mike Heilemann (162287), Barbara Müller (212640), Sebastian Malkusch (383895), Muranyi, Walter, Hans-Georg Kräusslich, Kräusslich, Hans-Georg, Sebastian Malkusch, Heilemann, Mike   +14 more
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NMR Studies of Viral Envelope Proteins [PDF]

, 2012
Detailed structural information about viral envelope proteins is necessary for a better understanding of the viral entry mechanism, as well as for the development of new and improved anti-viral therapies, especially those targeting the pre-fusion and ...
Jessica G. Celigoy (7986425)
core   +6 more sources

HIV-1 Envelope Glycoprotein at the Interface of Host Restriction and Virus Evasion

Viruses, 2019
Without viral envelope proteins, viruses cannot enter cells to start infection. As the major viral proteins present on the surface of virions, viral envelope proteins are a prominent target of the host immune system in preventing and ultimately ...
Saina Beitari, Yimeng Wang, Shan-Lu Liu, Chen Liang   +3 more
doaj   +1 more source

Partial Functional Rescue of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus Infectivity by Replacement of F Protein with GP64 from Autographa californica Multicapsid Nucleopolyhedrovirus [PDF]

, 2010
Two distinct envelope fusion proteins (EFPs) (GP64 and F) have been identified in members of the Baculoviridae family of viruses. F proteins are found in group II nucleopolyhedroviruses (NPVs) of alphabaculoviruses and in beta- and deltabaculoviruses ...
Feifei Yin, Shu Shen, Just M. Vlak, Fei Deng, Shen, S., Vlak, J.M., Deng, F., Manli Wang, Ying Tan, Yin, F.F., Hu, Z.H., Wang, M.L., Hualin Wang, Zhihong Hu, Tan, Y., Wang, H.L.   +15 more
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Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]

, 1980
Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Klenk, H, Gething, M. J., Koszinowski, Ulrich H., Gething, MJ, Waterfield, MD, M D Waterfield, U H Koszinowski, M J Gething, Koszinowski, UH, Klenk, H. D., H Allen, Allen, H, Gething, M, Koszinowski, U H, H D Klenk, Allen, H., Waterfield, M. D., Klenk, HD   +17 more
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Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]

, 2009
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr, Ulrich Koszinowski, Mühlbach, Hermine, Koszinowski, Ulrich H., Zsolt Ruzsics, Christian Mohr, Mohr, Christian A., Ruzsics, Zsolt, Hermine Mühlbach, Ulrich H. Koszinowski   +9 more
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The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Kien, F., Nicholls, JM, Bruzzone, R, Chan, C. M., Tsao, SW, Kien, F, Siu, Y. L., Escriou, N, Altmeyer, R., Nal, B., Nicholls, J. M., Chan, CM, Siu, YL, Lo, J, Peiris, J. S. M., Tsao, S. W., Teoh, KT, Nal, B, Teoh, K. T., Peiris, JSM, Altmeyer, R, Lo, J., Escriou, N., Bruzzone, R.   +23 more
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Determinants of the Bovine Leukemia Virus Envelope Glycoproteins Involved in Infectivity, Replication and Pathogenesis

Viruses, 2016
Interaction of viral envelope proteins with host cell membranes has been extensively investigated in a number of systems. However, the biological relevance of these interactions in vivo has been hampered by the absence of adequate animal models.
Alix de Brogniez, Jan Mast, Luc Willems
doaj   +1 more source

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery [PDF]

, 2013
BACKGROUND: Different cell types have distinctive patterns of chromosome positioning in the nucleus. Although ectopic affinity-tethering of specific loci can be used to relocate chromosomes to the nuclear periphery, endogenous nuclear envelope proteins ...
Vassiliki Lazou, Harrison, David J, Schirmer, Eric C, David J Harrison, Zuleger, Nikolaj, de Las Heras, Jose I, Wendy A Bickmore, Dzmitry G Batrakou, Lazou, Vassiliki, Batrakou, Dzmitry G, Jose I de las Heras, Bickmore, Wendy A, Nikolaj Zuleger, Shelagh Boyle, Kelly, David A, Korfali, Nadia, Nadia Korfali, Glenn E Morris, Eric C Schirmer, Boyle, Shelagh, David A Kelly, K Natalie Randles, Randles, K Natalie, Morris, Glenn E   +23 more
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