ViralFP: A Web Application of Viral Fusion Proteins. [PDF]
Front Med Technol, 2021 Viral fusion proteins are attached to the membrane of enveloped viruses (a group that includes Coronaviruses, Dengue, HIV and Influenza) and catalyze fusion between the viral and host membranes, enabling the virus to insert its genetic material into the ...
Moreira P +5 more
europepmc +10 more sources
Transmembrane Domains of Highly Pathogenic Viral Fusion Proteins Exhibit Trimeric Association In Vitro. [PDF]
mSphere, 2018 Enveloped viruses require viral fusion proteins to promote fusion of the viral envelope with a target cell membrane. To drive fusion, these proteins undergo large conformational changes that must occur at the right place and at the right time ...
Webb SR, Smith SE, Fried MG, Dutch RE.
europepmc +6 more sources
Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm [PDF]
Retrovirology, 2008 Enveloped viruses encode specialized fusion proteins which promote the merger of viral and cell membranes, permitting the cytosolic release of the viral cores.
Melikyan, Gregory B
core +8 more sources
Viral Membrane Fusion and the Transmembrane Domain [PDF]
Viruses, 2020 Initiation of host cell infection by an enveloped virus requires a viral-to-host cell membrane fusion event. This event is mediated by at least one viral transmembrane glycoprotein, termed the fusion protein, which is a key therapeutic target.
Barrett, Chelsea T. +1 more
core +4 more sources
Assembly and architecture of the EBV B cell entry triggering complex. [PDF]
PLoS Pathogens, 2014 Epstein-Barr Virus (EBV) is an enveloped double-stranded DNA virus of the gammaherpesvirinae sub-family that predominantly infects humans through epithelial cells and B cells.
Chen, Jia +10 more
core +11 more sources
Ezrin interacts with the SARS coronavirus spike protein and restrains infection at the entry stage [PDF]
, 2012 © 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Chen +79 more
core +15 more sources
Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]
, 2009 Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed +25 more
core +2 more sources
Mechanism of membrane fusion induced by vesicular stomatitis virus G protein [PDF]
, 2016 The glycoproteins (G proteins) of vesicular stomatitis virus (VSV) and related rhabdoviruses (e.g., rabies virus) mediate both cell attachment and membrane fusion.
Harrison, Stephen C. +6 more
core +2 more sources
Membrane fusion activity of vesicular stomatitis virus glycoprotein G is induced by low pH but not by heat or denaturant [PDF]
, 2003 The fusogenic envelope glycoprotein G of the rhabdovirus vesicular stomatitis virus (VSV) induces membrane fusion at acidic pH. At acidic pH the G protein undergoes a major structural reorganization leading to the fusogenic conformation.
Epand, Raquel F +4 more
core +1 more source
Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]
, 2009 The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K. +4 more
core +2 more sources