Results 41 to 50 of about 603,967 (361)

Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]

open access: yes, 2009
Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed   +25 more
core   +2 more sources

Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein

open access: yesmBio, 2022
Retroviral elements from endogenous retroviruses have functions in mammalian physiology. The best-known examples are the envelope proteins that function in placenta development and immune suppression.
Trevor T. Dean   +2 more
doaj   +1 more source

Receptor-Activated Binding of Viral Fusion Proteins to Target Membranes

open access: green, 2003
This chapter describes three assays to monitor receptor-induced association of the envelope glycoprotein (EnvA) of avian sarcoma/leukosis virus (ASLV) with target bilayers: (1) the original assay for monitoring binding of the EnvA ectodomain (EnvA-PI) to target membranes (liposomes), (2) a modified and miniaturized EnvA-PI-liposome binding assay, and ...
Laurie J. Earp   +3 more
openalex   +4 more sources

Mechanism of membrane fusion induced by vesicular stomatitis virus G protein [PDF]

open access: yes, 2016
The glycoproteins (G proteins) of vesicular stomatitis virus (VSV) and related rhabdoviruses (e.g., rabies virus) mediate both cell attachment and membrane fusion.
Harrison, Stephen C.   +6 more
core   +2 more sources

Structural Transition and Antibody Binding of EBOV GP and ZIKV E Proteins from Pre-Fusion to Fusion-Initiation State

open access: yesBiomolecules, 2018
Membrane fusion proteins are responsible for viral entry into host cells—a crucial first step in viral infection. These proteins undergo large conformational changes from pre-fusion to fusion-initiation structures, and, despite differences in viral
Anna Lappala   +8 more
doaj   +1 more source

Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]

open access: yes, 2009
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K.   +4 more
core   +2 more sources

Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Hantaviruses can cause hantavirus pulmonary syndrome or hemorrhagic fever with renal syndrome in humans. To enter cells, hantaviruses fuse their envelope membrane with host cell membranes.
Gonzalo P Barriga   +9 more
doaj   +1 more source

SARS-CoV-2 Fusion Peptide Conjugated to a Tetravalent Dendrimer Selectively Inhibits Viral Infection

open access: yesPharmaceutics, 2023
Fusion is a key event for enveloped viruses, through which viral and cell membranes come into close contact. This event is mediated by viral fusion proteins, which are divided into three structural and functional classes.
Carla Zannella   +10 more
doaj   +1 more source

The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]

open access: yes, 2016
Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S   +4 more
core   +2 more sources

Hydrophobic-at-Interface Regions in Viral Fusion Protein Ectodomains [PDF]

open access: yesBioscience Reports, 2000
In this chapter we shall describe how to apply the hydrophobicity-at-interface scale, as proposed by Wimley and White [Wimley, W. C. and White, S. H. (1996) Nature Struct. Biol. 3:842–848], to the detection of amino acid sequences of viral envelope glycoproteins putatively engaged in interactions with the target membranes.
José L. Nieva, Tatiana Suárez
openaire   +2 more sources

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