Results 11 to 20 of about 1,648,672 (312)

Viral infections [PDF]

open access: yesJournal of Clinical Pathology, 1976
Although rubella is the only virus which can be regarded in the strict sense of the term a teratogen, there is no convincing evidence that other viruses can cause fetal damage of varying severity. The risk to the fetus appears to depend on the nature of the infectious agent, the maternal immune status and the gestational age when infection takes place.
L, Weinstein, T W, Chang
openaire   +5 more sources

Dengue viral infections [PDF]

open access: yesPostgraduate Medical Journal, 2004
Abstract Dengue viral infections are one of the most important mosquito borne diseases in the world. They may be asymptomatic or may give rise to undifferentiated fever, dengue fever, dengue haemorrhagic fever (DHF), or dengue shock syndrome.
G N, Malavige   +3 more
openaire   +2 more sources

Next generation L2-based HPV vaccines cross-protect against cutaneous papillomavirus infection and tumor development

open access: yesFrontiers in Immunology, 2022
Licensed L1-VLP-based immunizations against high-risk mucosal human papillomavirus (HPV) types have been a great success in reducing anogenital cancers, although they are limited in their cross-protection against HPV types not covered by the vaccine ...
Melinda Ahmels   +10 more
doaj   +1 more source

MITAgating Viral Infection [PDF]

open access: yesImmunity, 2008
Two recent papers, one in this issue of Immunity (Zhong et al., 2008), report the identification of a membrane protein, termed MITA or STING, that activates the transcription factor IRF3 to induce type-I interferons to mitigate viral infection.
Zeng, Wenwen, Chen, Zhijian J.
openaire   +2 more sources

Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses

open access: yesCells, 2021
Host cell-intrinsic antiviral responses are largely mediated by pattern-recognition receptor (PRR) signaling and the interferon (IFN) system. The IFN regulatory factor (IRF) family of transcription factors takes up a central role in transcriptional ...
Sandra Wüst   +3 more
doaj   +1 more source

HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection. [PDF]

open access: yes, 2017
Antiviral innate host defenses against acute viral infections include suppression of host protein synthesis to restrict viral protein production.
Clarissa Santos Rocha   +9 more
core   +2 more sources

Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]

open access: yes, 2006
BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice   +5 more
core   +3 more sources

Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death

open access: yesCell Death and Disease, 2022
Properly responding to DNA damage is vital for eukaryotic cells, including the induction of DNA repair, growth arrest and, as a last resort to prevent neoplastic transformation, cell death.
David Y. Zander   +4 more
doaj   +1 more source

Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection [PDF]

open access: yes, 2017
Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection.
Ali   +23 more
core   +3 more sources

Perinatal viral infections [PDF]

open access: yesEuropean Journal of Clinical Microbiology, 1987
In comparison to older children and adults, neonates are immunologically incompetent. They are susceptible to infections caused by a variety of microorganisms, including bacteria, fungi and viruses. These infectious agents may be acquired by neonates either prenatally, during the intrapartum period or postnatally.
Prober, C. G., Arvin, A. M.
openaire   +2 more sources

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