Results 11 to 20 of about 18,538 (220)

Viral Metagenomics on Cerebrospinal Fluid [PDF]

Genes, 2019
Identifying the causative pathogen in central nervous system (CNS) infections is crucial for patient management and prognosis. Many viruses can cause CNS infections, yet screening for each individually is costly and time-consuming. Most metagenomic assays can theoretically detect all pathogens, but often fail to detect viruses because of their small ...
Edridge, Arthur W D, Deijs, Martin, van Zeggeren, Ingeborg E, Kinsella, Cormac M, Jebbink, Maarten F, Bakker, Margreet, van de Beek, Diederik, Brouwer, Matthijs C, van der Hoek, Lia   +8 more
openaire   +6 more sources

Exploring the viral world through metagenomics [PDF]

Current Opinion in Virology, 2011
Viral metagenomics, or shotgun sequencing of purified viral particles, has revolutionized the field of environmental virology by allowing the exploration of viral communities in a variety of sample types throughout the biosphere. The introduction of viral metagenomics has demonstrated that dominant viruses in environmental communities are not well ...
Rosario, Karyna, Breitbart, Mya
openaire   +4 more sources

Viral Metagenomics: MetaView Software [PDF]

, 2007
The purpose of this report is to design and develop a tool for analysis of raw sequence read data from viral metagenomics experiments. The tool should compare read sequences of known viral nucleic acid sequence data and enable a user to attempt to determine, with some degree of confidence, what virus groups may be present in the sample.
Zhou, Carol, Smith, Jason
openaire   +4 more sources

[Pathology and viral metagenomics, a recent history]. [PDF]

Medecine sciences : M/S, 2013
L’étude des maladies virales humaines, animales et végétales a récemment bénéficié du développement de la métagénomique en écologie. Cette approche, dite sans a priori, consiste à décrire le génome viral total, ou virome, d’une fraction d’un écosystème sans tenir compte de cibles moléculaires déjà connues.
Bernardo, Pauline, Albina, Emmanuel, Eloit, Marc, Roumagnac, Philippe   +3 more
openaire   +4 more sources

Exploring viral diversity in fermented vegetables through viral metagenomics [PDF]

Food Microbiology
Fermented vegetables are traditionally produced using the endogenous microorganisms present in raw ingredients. While the diversity of bacteria and fungi in fermented vegetables has been relatively well studied, phage communities remain largely unexplored.
Cantuti Gendre, Julia, Le Marrec, Claire, Chaillou, Stéphane, Omhover-Fougy, Lysiane, Landaud, Sophie, Dugat-Bony, Eric   +5 more
openaire   +4 more sources

Utilizing Viral Metagenomics to Characterize Pathogenic and Commensal Viruses in Pediatric Patients with Febrile Neutropenia. [PDF]

Viruses
Febrile neutropenia (FN) is one of the most common complications in pediatric oncology patients. It has a complex etiologic nature, which in the majority of cases remains unclear.
Sarana da Silva A, de Campos GM, Altizani GM, de Carvalho E, Barros AC, Cella E, Kashima S, Sampaio SC, Elias MC, Giovanetti M, Scrideli CA, Slavov SN.   +11 more
europepmc   +2 more sources

Integrating Viral Metagenomics into an Ecological Framework [PDF]

Annual Review of Virology, 2021
Viral metagenomics has expanded our knowledge of the ecology of uncultured viruses, within both environmental (e.g., terrestrial and aquatic) and host-associated (e.g., plants and animals, including humans) contexts. Here, we emphasize the implementation of an ecological framework in viral metagenomic studies to address questions in virology rarely ...
Pacifica, Sommers, Anushila, Chatterjee, Arvind, Varsani, Gareth, Trubl   +3 more
openaire   +2 more sources

Gut viral metagenomics identifies viral signatures and their role in depression. [PDF]

Front Microbiol
BackgroundThe gut microbiome has been implicated in the onset and progression of depression. Yet, the role of the gut virome in depression remains unexplored, and a diagnostic model has not been satisfactorily constructed.MethodsHerein, we analysed the gut virome profiles of 29 patients with depression and 33 healthy controls using bulk metagenome ...
Chen X, Wu J, Fan D, Zhang P, Li Y, Cao Y, Cao M.   +6 more
europepmc   +4 more sources

Viral Metagenomics for the Identification of Emerging Infections in Clinical Samples with Inconclusive Dengue, Zika, and Chikungunya Viral Amplification. [PDF]

Viruses, 2022
Viral metagenomics is increasingly being used for the identification of emerging and re-emerging viral pathogens in clinical samples with unknown etiology.
Souza JVC, Santos HO, Leite AB, Giovanetti M, Bezerra RDS, Carvalho E, Bernardino JST, Viala VL, Haddad R, Ciccozzi M, Alcantara LCJ, Sampaio SC, Covas DT, Kashima S, Elias MC, Slavov SN.   +15 more
europepmc   +2 more sources

Challenges in the analysis of viral metagenomes [PDF]

Virus Evolution, 2016
Genome sequencing technologies continue to develop with remarkable pace, yet analytical approaches for reconstructing and classifying viral genomes from mixed samples remain limited in their performance and usability. Existing solutions generally target expert users and often have unclear scope, making it challenging to critically evaluate their ...
Rose, R, Constantinides, B, Tapinos, A, Robertson, D, Prosperi, M   +4 more
openaire   +3 more sources