Results 41 to 50 of about 926,380 (171)

Characterizing Enterotypes in Human Metagenomics: A Viral Perspective [PDF]

open access: yesFrontiers in Microbiology, 2021
The diversity and high genomic mutation rates of viral species hinder our understanding of viruses and their contributions to human health. Viral enterotypes as a description of the gut virome, its characteristics have not been thoroughly studied. Here we investigated the human gut virome composition using previously published sequencing data of 2,690 ...
Li Song, Lu Zhang, Xiaodong Fang
openaire   +4 more sources

Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses

open access: yesmSphere, 2019
Diarrhea remains one of the most common causes of deaths in children. A limited number of studies have investigated the prevalence of enteric pathogens in Cameroon, and as in many other African countries, the cause of many diarrheal episodes remains ...
Claude Kwe Yinda   +9 more
doaj   +1 more source

Metagenomic identification of viral sequences in laboratory reagents [PDF]

open access: yesViruses, 2021
2. Abstract Metagenomic next-generation sequencing has transformed the discovery and diagnosis of infectious disease, with the power to characterize the complete ‘infectome’ (bacteria, viruses, fungi, parasites) of an individual host organism.
Ashleigh F. Porter   +4 more
openaire   +5 more sources

Novel highly divergent sapoviruses detected by metagenomics analysis in straw-colored fruit bats in CameroonDivergent bat sapoviruses

open access: yesEmerging Microbes and Infections, 2017
Sapoviruses (SaVs) belong to the Sapovirus genus, in the family Caliciviridae. They have been associated with gastroenteritis in humans and in pigs but not in other animals. In addition, some strains from pigs, chimpanzees and rodents show close sequence
Claude Kwe Yinda   +7 more
doaj   +1 more source

Biases in Viral Metagenomics-Based Detection, Cataloguing and Quantification of Bacteriophage Genomes in Human Faeces, a Review

open access: yesMicroorganisms, 2021
The human gut is colonised by a vast array of microbes that include bacteria, viruses, fungi, and archaea. While interest in these microbial entities has largely focused on the bacterial constituents, recently the viral component has attracted more ...
Julie Callanan   +5 more
semanticscholar   +1 more source

Impact of HIV infection and integrase strand transfer inhibitors-based treatment on the gut virome

open access: yesScientific Reports, 2022
Viruses are the most abundant components of the human gut microbiome with a significant impact on health and disease. The effects of human immunodeficiency virus (HIV) infection on gut virome has been scarcely analysed.
Pablo Villoslada-Blanco   +12 more
doaj   +1 more source

Deep Impact of Random Amplification and Library Construction Methods on Viral Metagenomics Results

open access: yesViruses, 2021
Clinical metagenomics is a broad-range agnostic detection method of pathogens, including novel microorganisms. A major limit is the low pathogen load compared to the high background of host nucleic acids.
B. Regnault   +5 more
semanticscholar   +1 more source

ContigExtender: a new approach to improving de novo sequence assembly for viral metagenomics data

open access: yesBMC Bioinformatics, 2021
Metagenomics is the study of microbial genomes for pathogen detection and discovery in human clinical, animal, and environmental samples via Next-Generation Sequencing (NGS).
Z. Deng, E. Delwart
semanticscholar   +1 more source

Whole Genome Analysis of Selected Human Group A Rotavirus Strains Revealed Evolution of DS-1-Like Single- and Double-Gene Reassortant Rotavirus Strains in Pakistan During 2015–2016

open access: yesFrontiers in Microbiology, 2019
Acute gastroenteritis due to group A rotaviruses (RVAs) is the leading cause of infant and childhood morbidity and mortality particularly in developing countries including Pakistan.
Asma Sadiq   +4 more
doaj   +1 more source

Improved diagnosis of viral encephalitis in adult and pediatric hematological patients using viral metagenomics.

open access: yesJournal of Clinical Virology, 2020
Metagenomic sequencing is a powerful technique that enables detection of the full spectrum of pathogens present in any specimen in a single test. Hence, metagenomics is increasingly being applied for detection of viruses in clinical cases with suspected ...
E. Carbo   +9 more
semanticscholar   +2 more sources

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