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Characterizing Enterotypes in Human Metagenomics: A Viral Perspective [PDF]
The diversity and high genomic mutation rates of viral species hinder our understanding of viruses and their contributions to human health. Viral enterotypes as a description of the gut virome, its characteristics have not been thoroughly studied. Here we investigated the human gut virome composition using previously published sequencing data of 2,690 ...
Li Song, Lu Zhang, Xiaodong Fang
openaire +4 more sources
Diarrhea remains one of the most common causes of deaths in children. A limited number of studies have investigated the prevalence of enteric pathogens in Cameroon, and as in many other African countries, the cause of many diarrheal episodes remains ...
Claude Kwe Yinda +9 more
doaj +1 more source
Metagenomic identification of viral sequences in laboratory reagents [PDF]
2. Abstract Metagenomic next-generation sequencing has transformed the discovery and diagnosis of infectious disease, with the power to characterize the complete ‘infectome’ (bacteria, viruses, fungi, parasites) of an individual host organism.
Ashleigh F. Porter +4 more
openaire +5 more sources
Sapoviruses (SaVs) belong to the Sapovirus genus, in the family Caliciviridae. They have been associated with gastroenteritis in humans and in pigs but not in other animals. In addition, some strains from pigs, chimpanzees and rodents show close sequence
Claude Kwe Yinda +7 more
doaj +1 more source
The human gut is colonised by a vast array of microbes that include bacteria, viruses, fungi, and archaea. While interest in these microbial entities has largely focused on the bacterial constituents, recently the viral component has attracted more ...
Julie Callanan +5 more
semanticscholar +1 more source
Impact of HIV infection and integrase strand transfer inhibitors-based treatment on the gut virome
Viruses are the most abundant components of the human gut microbiome with a significant impact on health and disease. The effects of human immunodeficiency virus (HIV) infection on gut virome has been scarcely analysed.
Pablo Villoslada-Blanco +12 more
doaj +1 more source
Deep Impact of Random Amplification and Library Construction Methods on Viral Metagenomics Results
Clinical metagenomics is a broad-range agnostic detection method of pathogens, including novel microorganisms. A major limit is the low pathogen load compared to the high background of host nucleic acids.
B. Regnault +5 more
semanticscholar +1 more source
ContigExtender: a new approach to improving de novo sequence assembly for viral metagenomics data
Metagenomics is the study of microbial genomes for pathogen detection and discovery in human clinical, animal, and environmental samples via Next-Generation Sequencing (NGS).
Z. Deng, E. Delwart
semanticscholar +1 more source
Acute gastroenteritis due to group A rotaviruses (RVAs) is the leading cause of infant and childhood morbidity and mortality particularly in developing countries including Pakistan.
Asma Sadiq +4 more
doaj +1 more source
Metagenomic sequencing is a powerful technique that enables detection of the full spectrum of pathogens present in any specimen in a single test. Hence, metagenomics is increasingly being applied for detection of viruses in clinical cases with suspected ...
E. Carbo +9 more
semanticscholar +2 more sources

