Results 51 to 60 of about 605,993 (221)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Correction: Mbigha Donfack et al. Aedes Mosquito Virome in Southwestern Cameroon: Lack of Core Virome, But a Very Rich and Diverse Virome in Ae. africanus Compared to Other Aedes Species. Viruses 2024, 16, 1172

Viruses
In the original publication [...]
Karelle Celes Mbigha Donfack, Lander De Coninck, Stephen Mbigha Ghogomu, Jelle Matthijnssens   +3 more
doaj   +1 more source

Virseqimprover: an integrated pipeline for viral contig error correction, extension, and annotation [PDF]

PeerJ
Despite the recent surge of viral metagenomic studies, it remains a significant challenge to recover complete virus genomes from metagenomic data. The majority of viral contigs generated from de novo assembly programs are highly fragmented, presenting ...
Haoqiu Song, Saima Sultana Tithi, Connor Brown, Frank O. Aylward, Roderick Jensen, Liqing Zhang   +5 more
doaj   +2 more sources

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Aedes Mosquito Virome in Southwestern Cameroon: Lack of Core Virome, But a Very Rich and Diverse Virome in Ae. africanus Compared to Other Aedes Species

Viruses
In Cameroon, Aedes mosquitoes transmit various arboviruses, posing significant health risks. We aimed to characterize the Aedes virome in southwestern Cameroon and identify potential core viruses which might be associated with vector competence.
Karelle Celes Mbigha Donfack, Lander De Coninck, Stephen Mbigha Ghogomu, Jelle Matthijnssens   +3 more
doaj   +1 more source

Structural characterization of a soil viral auxiliary metabolic gene product – a functional chitosanase

Nature Communications, 2022
Metagenomics is revealing auxiliary metabolic genes (AMGs) in soil viral genomes. Here, authors solve the crystal structure for a soil viral AMG product, free and ligand bound, and show the protein can decompose chitin, a common carbon polymer.
Ruonan Wu, Clyde A. Smith, Garry W. Buchko, Ian K. Blaby, David Paez-Espino, Nikos C. Kyrpides, Yasuo Yoshikuni, Jason E. McDermott, Kirsten S. Hofmockel, John R. Cort, Janet K. Jansson   +10 more
doaj   +1 more source

Viral Metagenomics for the Identification of Emerging Infections in Clinical Samples with Inconclusive Dengue, Zika, and Chikungunya Viral Amplification

Viruses, 2022
Viral metagenomics is increasingly being used for the identification of emerging and re-emerging viral pathogens in clinical samples with unknown etiology.
Juliana Vanessa Cavalcante Souza, Hazerral de Oliveira Santos, Anderson Brandão Leite, Marta Giovanetti, Rafael dos Santos Bezerra, Eneas de Carvalho, Jardelina de Souza Todão Bernardino, Vincent Louis Viala, Rodrigo Haddad, Massimo Ciccozzi, Luiz Carlos Junior Alcantara, Sandra Coccuzzo Sampaio, Dimas Tadeu Covas, Simone Kashima, Maria Carolina Elias, Svetoslav Nanev Slavov   +15 more
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Bioinformatics for Viral Metagenomics [PDF]

Journal of Data Mining in Genomics & Proteomics, 2013
Detection of the presence of known and unknown viruses in biospecimens is today routinely performed using viral metagenomics. Because the sequencing speed and cost per base is rapidly declining with new next generation sequencing technologies, such as HiSeq (Illumina), 454 GS FLX (Roche), SOLiD (ABI) and Ion Torrent Proton (Life Technologies), the ...
openaire   +1 more source

Metagenomics Study of the Commercial Tomato Virome Focused on Virus Species of Epidemiological Interest

Viruses
Plant viruses have detrimental effects on commercial tomato cultivation leading to severe economic consequences. Viral metagenomics studies provide the opportunity to examine in depth the virome composition of a sample set without any pre-existing ...
Zafeiro Zisi, Isabel Ruiz Movilla, Nikolas Basler, Lila Close, Lucas Ghijselings, Robby Van der Hoeven, Maria Ioanna Papadaki, Ester Rabbinowitsch, Fiona Van Reeth, Jill Swinnen, Elise Vogel, Christine Vos, Inge Hanssen, Jelle Matthijnssens   +13 more
doaj   +1 more source