Results 51 to 60 of about 928,374 (298)
Reviews in Medical Virology, 2007 AbstractCharacterisation of new viruses is often hindered by difficulties in amplifying them in cell culture, limited antigenic/serological cross‐reactivity or the lack of nucleic acid hybridisation to known viral sequences. Numerous molecular methods have been used to genetically characterise new viruses without prior in vitro replication or the use ...
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Challenges in the analysis of viral metagenomes [PDF]
Virus Evolution, 2016 Genome sequencing technologies continue to develop with remarkable pace, yet analytical approaches for reconstructing and classifying viral genomes from mixed samples remain limited in their performance and usability. Existing solutions generally target expert users and often have unclear scope, making it challenging to critically evaluate their ...
Rose, R +4 more
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Diagnostic metagenomics : potential applications to bacterial, viral and parasitic infections [PDF]
, 2014 The term 'shotgun metagenomics' is applied to the direct sequencing of DNA extracted from a sample without culture or target-specific amplification or capture.
M. J. Pallen, Pallen, Mark J.
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Comparative metagenomics of Daphnia symbionts [PDF]
, 2009 BACKGROUND: Shotgun sequences of DNA extracts from whole organisms allow a comprehensive assessment of possible symbionts. The current project makes use of four shotgun datasets from three species of the planktonic freshwater crustaceans Daphnia: one ...
Ebert, Dieter +23 more
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EBI metagenomics—a new resource for the analysis and archiving of metagenomic data [PDF]
, 2013 Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil ...
Vaughan, Daniel +26 more
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Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer [PDF]
, 2014 Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community.
Emma L. Doughty +17 more
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Parasites & Vectors, 2021 The Zika virus (ZIKV) epidemic of 2015/2016 spread throughout numerous countries. It emerged in mainland Latin America and spread to neighboring islands, including the Caribbean island of Barbados.
J. Thannesberger +11 more
semanticscholar +1 more source
F1000Research, 2023 Background A high prevalence of onchocerciasis-associated epilepsy (OAE) has been observed in onchocerciasis-endemic areas with high ongoing Onchocerca volvulus transmission. However, the pathogenesis of OAE remains to be elucidated.
Robert Colebunders +10 more
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Viral metagenomics and blood safety
Transfusion Clinique et Biologique, 2016 The characterization of the human blood-associated viral community (also called blood virome) is essential for epidemiological surveillance and to anticipate new potential threats for blood transfusion safety. Currently, the risk of blood-borne agent transmission of well-known viruses (HBV, HCV, HIV and HTLV) can be considered as under control in high ...
Sauvage, V., Eloit, M.
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African army ants at the forefront of virome surveillance in a remote tropical forest
Peer Community Journal, 2023 In this study, we used a predator-enabled metagenomics strategy to sample the virome of a remote and difficult-to-access densely forested African tropical region.
Fritz, Matthieu +23 more
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