Results 21 to 30 of about 18,538 (220)
Reviews in Medical Virology, 2007 AbstractCharacterisation of new viruses is often hindered by difficulties in amplifying them in cell culture, limited antigenic/serological cross‐reactivity or the lack of nucleic acid hybridisation to known viral sequences. Numerous molecular methods have been used to genetically characterise new viruses without prior in vitro replication or the use ...
openaire +2 more sources
Characterizing Enterotypes in Human Metagenomics: A Viral Perspective [PDF]
Frontiers in Microbiology, 2021 The diversity and high genomic mutation rates of viral species hinder our understanding of viruses and their contributions to human health. Viral enterotypes as a description of the gut virome, its characteristics have not been thoroughly studied. Here we investigated the human gut virome composition using previously published sequencing data of 2,690 ...
Li Song, Lu Zhang, Xiaodong Fang
openaire +4 more sources
Diagnostic metagenomics : potential applications to bacterial, viral and parasitic infections [PDF]
, 2014 The term 'shotgun metagenomics' is applied to the direct sequencing of DNA extracted from a sample without culture or target-specific amplification or capture.
M. J. Pallen, Pallen, Mark J.
core +1 more source
Metagenomic identification of viral sequences in laboratory reagents [PDF]
Viruses, 2021 2. Abstract Metagenomic next-generation sequencing has transformed the discovery and diagnosis of infectious disease, with the power to characterize the complete ‘infectome’ (bacteria, viruses, fungi, parasites) of an individual host organism.
Ashleigh F. Porter +4 more
openaire +5 more sources
Comparative metagenomics of Daphnia symbionts [PDF]
, 2009 BACKGROUND: Shotgun sequences of DNA extracts from whole organisms allow a comprehensive assessment of possible symbionts. The current project makes use of four shotgun datasets from three species of the planktonic freshwater crustaceans Daphnia: one ...
Ebert, Dieter +23 more
core +1 more source
A library preparation optimized for metagenomics of RNA viruses [PDF]
, 2021 Our understanding of the viral communities associated to animals has not yet reached the level attained on the bacteriome. This situation is due to, among others, technical challenges in adapting metagenomics using high‐throughput sequencing to the study
Etienne Loire +39 more
core +1 more source
EBI metagenomics—a new resource for the analysis and archiving of metagenomic data [PDF]
, 2013 Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil ...
Vaughan, Daniel +26 more
core +1 more source
454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology [PDF]
, 2010 Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies.
Allison, Heather E +23 more
core +1 more source
A Review on Viral Metagenomics in Extreme Environments. [PDF]
Front Microbiol, 2019 Viruses are the most abundant biological entities in the biosphere, and have the ability to infect Bacteria, Archaea, and Eukaryotes. The virome is estimated to be at least ten times more abundant than the microbiome with 107 viruses per milliliter and 109 viral particles per gram in marine waters and sediments or soils, respectively. Viruses represent
Dávila-Ramos S +9 more
europepmc +6 more sources
Biodiversity and distribution of polar freshwater DNA viruses [PDF]
, 2015 Viruses constitute the most abundant biological entities and a large reservoir of genetic diversity on Earth. Despite the recent surge in their study, our knowledge on their actual biodiversity and distribution remains sparse.
López-Bueno, Alberto +4 more
core +1 more source