Results 131 to 140 of about 35,570 (216)

Picornavirus 2C proteins: structure-function relationships and interactions with host factors

Frontiers in Cellular and Infection Microbiology
Picornaviruses, which are positive-stranded, non-enveloped RNA viruses, are known to infect people and animals with a broad spectrum of diseases. Among the nonstructural proteins in picornaviruses, 2C proteins are highly conserved and exhibit multiple ...
Chunhui Yin, Chunhui Yin, Chunhui Yin, Haomiao Zhao, Haomiao Zhao, Haomiao Zhao, Xiaoyi Xia, Xiaoyi Xia, Zhengyang Pan, Zhengyang Pan, Daoqun Li, Daoqun Li, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +14 more
doaj   +1 more source

Mapping the Landscape of Host-Pathogen Coevolution: HLA Class I Binding and Its Relationship with Evolutionary Conservation in Human and Viral Proteins [PDF]

, 2011
The high diversity of HLA binding preferences has been driven by the sequence diversity of short segments of relevant pathogenic proteins presented by HLA molecules to the immune system.
Jojic, N., Hertz, T., Nolan, D., John, M., Gaudieri, S., Phillips, E.J., James, I., Huang, J.C., Riadi, G., Mallal, S.   +9 more
core   +1 more source

Interfering with interferon: developing a reporter system to study the interaction between hepatitus C viral proteins and the interferon signalling pathway [PDF]

, 2008
PhDThe aim of the project was to investigate the mechanism by which HCV evades therapeutic IFN treatment. This involved the development of novel testing systems and their application to patient samples.
Jones, Meleri
core  

Putative Fusion-Associated Small Transmembrane (FAST) Proteins Encoded by Viruses of Pistolviridae, Order Ghabrivirales, Identified from In Silico Analyses

Viruses
Fusion-associated small transmembrane (FAST) proteins are viral nonstructural proteins known to be encoded by specific members of the Spinareoviridae, specifically within the Aquareovirus and Orthoreovirus genera.
Racheal Amono, Turhan Markussen, Øystein Evensen, Aase B. Mikalsen   +3 more
doaj   +1 more source

Heat shock protein 70 enhances viral replication by stabilizing Senecavirus A nonstructural proteins L and 3D

Veterinary Research
AbstractSenecavirus A (SVA) is an emerging pathogen that causes idiopathic vesicular infections in pig herds, posing a potential threat to their production performance. Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in host homeostasis under both physiological and stress conditions.
Lei Hou, Penghui Zeng, Zhi Wu, Xiaoyu Yang, Jinshuo Guo, Yongyan Shi, Jiangwei Song, Jianwei Zhou, Jue Liu   +8 more
openaire   +3 more sources

Characterization of the major immediate-early polypeptides encoded by murine cytomegalovirus [PDF]

, 1985
The immediate-early (IE) infected cell proteins induced by the murine cytomegalovirus (Smith strain) were studied. These polypeptides were identified as IE proteins by their synthesis in the presence of actinomycin D after removal from a protein ...
Fibi, Mathias R., Koszinowski, Ulrich H., Keil, Günther M.   +2 more
core  

Interaction of rotavirus nonstructural protein NSP5 with the viral replication complex

, 2008
Rotavirus morphogenesis starts in intracellular inclusion bodies called viroplasms, where synthesis of the11 dsRNA genome segments and their packaging in new viral particles take place. RNA replication is mediated by several viral proteins, of which VP1, the RNA-dependent RNA polymerase, and VP2, the core scaffolding protein, were shown to be ...
openaire   +1 more source

[Preparation and properties of monoclonal antibodies to tick-borne encephalitis viral nonstructural proteins].

Voprosy virusologii, 1998
Hybridomas secreting monoclonal antibodies (Mab) to tick-borne encephalitis (TBE) virus are obtained. Immunodiffusion showed that 3 Mabs to TBE protein NS3 belong to class IgM and the rest to IgG1. Mabs to TBE protein NS1 were tested in hemagglutination inhibition, complement fixation, neutralization, and protection tests. Only 1 hybridoma produced Mab
V A, Matveeva, E Iu, Dobrikova, N A, Tsekhanovskaia, R V, Popova, E K, Pressman, A S, Karavanov, L E, Matveev   +6 more
openaire   +1 more source

Interferon, virus vaccines and antiviral drugs [PDF]

, 2008
The emergence of viruses with zoonotic potential, i.e. with the potential ability to cross species barriers to infect unnatural hosts, poses a huge threat to humans.
Rodrigues, Ana Mara Lopes
core  

PfDNV nonstructural proteins suppress viral RNA splicing.

The Journal of Sericultural Science of Japan, 2000
YAMAGISHI, JUNYA, ASANO, SHINICHIRO, SAHARA, KEN, IIZUKA, TOSHIHIKO, BANDO, HISANORI   +4 more
openaire   +1 more source