Results 121 to 130 of about 2,054,524 (213)

Exploring the genetic basis of Newcastle disease virus in chickens: a comprehensive review

open access: yesFrontiers in Immunology
Newcastle disease (ND) is one of the most serious viral diseases affecting chickens and is caused by Newcastle disease virus (NDV), an avian paramyxovirus serotype-1.
Haile Berihulay   +7 more
doaj   +1 more source

Aptamer as a therapeutic agent for dengue infections

open access: yesVirology Journal
Dengue virus (DENV) poses a significant global health burden, with current treatments being limited and primarily supportive. Aptamers are an emerging class of molecular recognition elements that are cheaper, less immunogenic and have no batch-to-batch ...
Nur Aida Laili Mislan   +6 more
doaj   +1 more source

Porcine reproductive and respiratory syndrome virus antagonizes the host restriction factor SHFL to sustain viral programmed ribosomal frameshifting and replication

open access: yesJournal of Virology
The global pandemic of porcine reproductive and respiratory syndrome virus (PRRSV) and its continuous evolution pose a sustained threat to the swine industry, underscoring the urgent need for a broad-spectrum antiviral strategy.
Kefan Bu   +6 more
doaj   +1 more source

Picornavirus 2C proteins: structure-function relationships and interactions with host factors

open access: yesFrontiers in Cellular and Infection Microbiology
Picornaviruses, which are positive-stranded, non-enveloped RNA viruses, are known to infect people and animals with a broad spectrum of diseases. Among the nonstructural proteins in picornaviruses, 2C proteins are highly conserved and exhibit multiple ...
Chunhui Yin   +14 more
doaj   +1 more source

Zika virus and host protein interactions for understanding molecular mechanisms of pathogenesis and therapeutic development

open access: yesFrontiers in Cellular and Infection Microbiology
Zika virus (ZIKV) causes severe neurological disease, including microcephaly and Guillain-Barré syndrome, through complex interactions with host cell proteins.
Xiaodong Han   +6 more
doaj   +1 more source

Sequence analysis of the small (s) RNA segment of viruses in the genus Orthobunyavirus [PDF]

open access: yes, 2008
Viruses in the genus Orthobunyavirus (family Bunyaviridae) are classified serologically into 18 serogroups. The viruses have a tripartite genome of negative sense RNA composed of large (L), medium (M) and small (S) segments.
Mohamed, Maizan
core   +1 more source

Putative Fusion-Associated Small Transmembrane (FAST) Proteins Encoded by Viruses of Pistolviridae, Order Ghabrivirales, Identified from In Silico Analyses

open access: yesViruses
Fusion-associated small transmembrane (FAST) proteins are viral nonstructural proteins known to be encoded by specific members of the Spinareoviridae, specifically within the Aquareovirus and Orthoreovirus genera.
Racheal Amono   +3 more
doaj   +1 more source

Heat shock protein 70 enhances viral replication by stabilizing Senecavirus A nonstructural proteins L and 3D

open access: yesVeterinary Research
AbstractSenecavirus A (SVA) is an emerging pathogen that causes idiopathic vesicular infections in pig herds, posing a potential threat to their production performance. Heat shock protein 70 (Hsp70) is a molecular chaperone that plays an important role in host homeostasis under both physiological and stress conditions.
Lei Hou   +8 more
openaire   +3 more sources

Interaction of rotavirus nonstructural protein NSP5 with the viral replication complex

open access: yes, 2008
Rotavirus morphogenesis starts in intracellular inclusion bodies called viroplasms, where synthesis of the11 dsRNA genome segments and their packaging in new viral particles take place. RNA replication is mediated by several viral proteins, of which VP1, the RNA-dependent RNA polymerase, and VP2, the core scaffolding protein, were shown to be ...
openaire   +1 more source

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