Results 101 to 110 of about 35,570 (216)

Multiomics Identification and Validation of an Integrin–Extracellular Matrix Network Driving Respiratory Syncytial Virus‐Induced Lung Injury and Repair

MedComm, Volume 7, Issue 7, July 2026.
This graphical abstract depicts the dynamic progression from acute lung inflammation to fibrotic repair following RSV infection. Multiomics analysis uncovers a central regulatory network coordinating key pathways including coagulation, extracellular matrix deposition, integrin signaling, and cytoskeletal reorganization.
Lili Zhou, Hua Guo, Xiaofeng Yu, Yu Ran, Ruiqi Liu, Jiali Zhu, Ran Li, Jie Xu, Leshi Chen, Yongliang Zhu, Long Zhang, Zhenjiang Bai, Fangfang Zhou   +12 more
wiley   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway.

PLoS Pathogens, 2015
Chikungunya virus (CHIKV), the causative agent of a major epidemic spanning five continents, is a positive stranded mRNA virus that replicates using the cell's cap-dependent translation machinery.
Pierre-Emmanuel Joubert, Kenneth Stapleford, Florence Guivel-Benhassine, Marco Vignuzzi, Olivier Schwartz, Matthew L Albert   +5 more
doaj   +1 more source

Development of a Multivalent Kunjin Virus Reporter Virus-Like Particle System Inducing Seroconversion for Ebola and West Nile Virus Proteins in Mice

Microorganisms, 2020
Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). The virus has a single-strand positive-sense RNA genome that encodes a polyprotein.
Pham-Tue-Hung Tran, Naveed Asghar, Urban Höglund, Olivia Larsson, Lars Haag, Ali Mirazimi, Magnus Johansson, Wessam Melik   +7 more
doaj   +1 more source

First Serological Evidence of Foot‐and‐Mouth Disease Virus (FMDV) Infection Among Sheep and Goats in Selected Districts of Central Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Serological surveillance revealed foot‐and‐mouth disease virus (FMDV) exposure for the first time in sheep and goats across the studied districts of Bangladesh, highlighting their critical role in FMD epidemiology. These findings emphasize the importance of including sheep and goats in national FMD surveillance and control programmes.
Tahmina Sikder, Md. Jisan Ahmed, Basant Saud, Tasmiah Tarin, Md. Imran Hossain, Anowar Hossen, Mohammed Abdus Samad, Mohammad Rafiqul Islam, Munazah Shahzad, Nadeem Shabir, Won‐Il Kim, Amina Khatun   +11 more
wiley   +1 more source

Functional studies on the rotavirus non-structural proteins NSP5 and NSP6 [PDF]

The rotavirus replication cycle has not been fully characterised, one vital stage of virus replication involves large cytoplasmic occlusion bodies termed viroplasms.
Rainsford, Edward
core  

Implicações do peptídeo conservado E250-270 da proteína "E" na infectividade do vírus da dengue [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2014Os vírus de genoma RNA apresentam uma ampla variabilidade genética, devido à ...
Fleith, Renata Cristina
core  

Expression of the murine norovirus (MNV) ORF1 polyprotein is sufficient to induce apoptosis in a virus-free cell model [PDF]

, 2014
Investigations into human norovirus infection, replication and pathogenesis, as well as the development of potential antiviral agents, have been restricted by the lack of a cell culture system for human norovirus.
Morgan R. Herod (530748), Rachel J Skilton, Cynthia A. Prince (530749), Morgan R Herod, Clarke, IN, Vernon K. Ward (333594), Skilton, RJ, Herod, Morgan R., Omar Salim, Clarke, Ian N., Ian N Clarke, Rachel J. Skilton (204339), Ian N. Clarke (46223), Ward, Vernon K., Prince, Cynthia A., Vernon K Ward, Lambden, PR, Lambden, Paul R., Ward, VK, Paul R. Lambden (46224), Skilton, Rachel J., Paul R Lambden, Omar Salim (46222), Prince, CA, Cynthia A Prince, Herod, MR, Salim, O, Salim, Omar   +27 more
core   +1 more source

Nonstructural 5A Protein of Hepatitis C Virus Interacts with Pyruvate Carboxylase and Modulates Viral Propagation

PLoS ONE, 2013
Hepatitis C virus (HCV) is highly dependent on cellular factors for its own propagation. By employing tandem affinity purification method, we identified pyruvate carboxylase (PC) as a cellular partner for NS5A protein. NS5A interacted with PC through the N-terminal region of NS5A and the biotin carboxylase domain of PC.
Yim, Seung-Ae, Lim, Yun-Sook, Kim, Jong-Wook, Hwang, Soon B.   +3 more
openaire   +5 more sources

Subcellular location and protein interactions of the infectious bronchitis virus gene 3 and 5 accessory proteins [PDF]

The avian coronavirus infectious bronchitis virus (IBV) expresses four nonstructural, non-gene 1 proteins (3a, 3b, 5a and 5b) which have been shown to be dispensable for virus replication in cell culture.
Davies, Marc Tudor
core