Results 91 to 100 of about 2,054,524 (213)

Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. [PDF]

, 2012
BACKGROUND: Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus of the Reoviridae family, which encodes its genes in ten linear dsRNA segments.
Roy Polly, Boyce, Mark, Roy, Polly, Celma, Cristina CP, Cristina C P Celma, Boyce Mark, Mark Boyce, Polly Roy, Celma Cristina C P   +8 more
core   +1 more source

Recent Advances in Dengue Fever Based on Serotypes, Virulence Factors, Prevention, and Treatment: A Comprehensive Review [PDF]

Disease and Diagnosis
Dengue fever, a Flaviviridae viral disease, exhibits various clinical symptoms, such as hemorrhagic fever, and is influenced by multiple factors. This comprehensive review aims to explore different aspects of dengue fever.
Ali Salimi Asl, Narjes Seddighi, Amir Mohammad Barani, Mahla Naderi Nasab, Elham Barahimi   +4 more
doaj   +1 more source

Magnetic Bead‐Based Ligand Fishing Identifies SARS‐CoV‐2 Main Protease Inhibitors From Reynoutria japonica

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A magnetic bead‐based ligand fishing workflow using immobilized SARS‐CoV‐2 Mpro was coupled with UPLC‐Q‐Exactive‐Orbitrap‐MS/MS to screen potential Mpro‐binding constituents directly from a crude Reynoutria japonica extract. Eight compounds were captured and annotated, of which six showed concentration‐dependent Mpro inhibition, with resveratrol ...
Yujing Huang, Chenjing Tian, Zhipeng Gu, Jinlian Liang, Duntao Zu, Jianni Yang, Wanrong Zhang, Nina Ren, Junxia Zheng   +8 more
wiley   +1 more source

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

Akabane virus nonstructural protein NSm regulates viral growth and pathogenicity in a mouse model

Journal of Veterinary Medical Science, 2016
The biological function of a nonstructural protein, NSm, of Akabane virus (AKAV) is unknown. In this study, we generated a series of NSm deletion mutant viruses by reverse genetics and compared their phenotypes. The mutant in which the NSm coding region was almost completely deleted could not be rescued, suggesting that NSm plays a role in virus ...
ISHIHARA, Yukari, SHIODA, Chieko, BANGPHOOMI, Norasuthi, SUGIURA, Keita, SAEKI, Kohei, TSUDA, Shumpei, IWANAGA, Tatsuya, TAKENAKA-UEMA, Akiko, KATO, Kentaro, MURAKAMI, Shin, UCHIDA, Kazuyuki, AKASHI, Hiroomi, HORIMOTO, Taisuke   +12 more
openaire   +3 more sources

The HLA-II immunopeptidome of SARS-CoV-2

Cell Reports
Summary: Targeted synthetic vaccines have the potential to transform our response to viral outbreaks, yet the design of these vaccines requires a comprehensive knowledge of viral immunogens. Here, we report severe acute respiratory syndrome coronavirus 2
Shira Weingarten-Gabbay, Da-Yuan Chen, Siranush Sarkizova, Hannah B. Taylor, Matteo Gentili, Gabrielle M. Hernandez, Leah R. Pearlman, Matthew R. Bauer, Charles M. Rice, Karl R. Clauser, Nir Hacohen, Steven A. Carr, Jennifer G. Abelin, Mohsan Saeed, Pardis C. Sabeti   +14 more
doaj   +1 more source

Culture‐Negative Septic Pulmonary Embolism Secondary to Lower‐Limb Cellulitis Following Recent Dengue Fever Complicated by Hydropneumothorax: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Secondary bacterial infection and septic pulmonary embolism should be considered in patients recovering from dengue fever who develop focal soft‐tissue infection, respiratory symptoms, or markedly elevated inflammatory markers. Characteristic radiological findings may establish the diagnosis even when blood cultures are negative and infective ...
Faiza Arif, Mariyah Saqib Qureshi, Sajjad Khan, Malaika Usman, Umama Rehman, Aiyna Usman, Bilal Wazir Khan, Kashif Yousaf   +7 more
wiley   +1 more source

The small genome segment of Bunyamwera orthobunyavirus harbours a single transcription-termination signal [PDF]

, 2012
Transcription termination of the mRNA produced from the small (S) genome segment of Bunyamwera orthobunyavirus (BUNV) has previously been mapped to two cis-acting sequences located within the 5′ UTR using a virus-free replication assay.
Elliott, Richard Michael, Blakqori, G., Lowen, Anice C., Lowen, A.C., Elliott, R.M., Blakqori, Gjon   +5 more
core   +1 more source

Mapping mutational fitness effects across the coxsackievirus B3 proteome reveals distinct profiles of mutation tolerability.

PLoS Biology
RNA viruses have notoriously high mutation rates due to error-prone replication by their RNA polymerase. However, natural selection concentrates variability in a few key viral proteins.
Beatriz Álvarez-Rodríguez, Sebastian Velandia-Álvarez, Christina Toft, Ron Geller   +3 more
doaj   +1 more source

Molecularly imprinted polymers based electrochemical sensors for biomarker detection in biofluids

InfoScience, Volume 3, Issue 3, September 2026.
This review systematically summarizes the evolution of molecularly imprinted polymer electrochemical sensors from bulk structures to advanced nano‐imprinted architectures. It decouples the complex matrix effects of clinical biofluids and evaluates interfacial engineering strategies for anti‐biofouling.
Tianrui Zhu, Guobao Yao, Haoming Jiang, Yuan Gao, Yinchao Zhao, Hao Shen, Dequn Wu, Qifeng Lu   +7 more
wiley   +1 more source