Results 91 to 100 of about 47,745 (223)

Measles Virus Nonstructural C Protein Modulates Viral RNA Polymerase Activity by Interacting with Host Protein SHCBP1 [PDF]

Journal of Virology, 2013
ABSTRACT Most viruses possess strategies to circumvent host immune responses. The measles virus (MV) nonstructural C protein suppresses the interferon response, thereby allowing efficient viral growth, but its detailed mechanism has been unknown.
Minako, Ito, Masaharu, Iwasaki, Makoto, Takeda, Takanori, Nakamura, Yusuke, Yanagi, Shinji, Ohno   +5 more
openaire   +2 more sources

MAVS Is essential for primary CD4 + T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection [PDF]

, 2017
The use of pathogen recognition receptor (PRR) agonists and the molecular mechanisms involved have been the major focus of research in individual vaccine development.
Barrett, Alan D, Diamond, Michael S, Fang, Rong, Gale, Michael, Jr, Lazear, Helen M, Li, Li, Luo, Huanle, Paessler, Slobodan, Peng, Bi-Hung, Wang, Tian, Winkelmann, Evandro, Xie, Guorui   +11 more
core   +3 more sources

A Framework for Emergency Department–Integrated Hepatitis C Test‐and‐Treat in the United States

Journal of Viral Hepatitis, Volume 33, Issue 6, June 2026.
ABSTRACT Despite the availability of curative, direct‐acting antiviral therapy, hepatitis C virus elimination remains incomplete. Losses across the care cascade continue to limit impact, from initial diagnosis to sustained virologic response. Fewer than 1/3 of individuals ultimately achieve cure. These gaps reflect a delivery system that does not align
Saeed S. Graham
wiley   +1 more source

Complementation of a Deletion in the Rubella Virus P150 Nonstructural Protein by the Viral Capsid Protein [PDF]

Journal of Virology, 2003
ABSTRACT Rubella virus (RUB) replicons with an in-frame deletion of 507 nucleotides between two Not I sites in the P150 nonstructural protein (Δ Not I) do not replicate (as detected by expression of a reporter gene encoded by the replicon) but can be amplified by wild-type helper ...
Wen-Pin, Tzeng, Teryl K, Frey
openaire   +2 more sources

Host immune response to cytomegalovirus [PDF]

, 1987
To confirm that immediate-early (IE) genes of murine cytomegalovirus (MCMV) give rise to antigens recognized by specific cytolytic T lymphocytes (CTL), a 10.8-kilobase fragment of MCMV DNA which is abundantly transcribed at IE times was transfected into ...
Keil, Günther M., Koszinowski, Ulrich H., Reddehase, Matthias J., Schickedanz, Jörg   +3 more
core  

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog [PDF]

, 2009
Alcohol synergistically enhances the progression of liver disease and the risk for liver cancer caused by hepatitis C virus (HCV). However, the molecular mechanism of this synergy remains unclear.
Asahina, Kinji, Deshaies, Raymond, Duan, Lewei, Dynnyk, Alla, Govindarajan, Sugantha, Lai, Michael M.-C., Liu, Helene Minyi, Machida, Keigo, Miyake, Kensuke, Mkrtchyan, Hasmik, Ou, Jing-hsiung James, Ray, Ratna, Seki, Ekihiro, Tsukamoto, Hidekazu   +13 more
core   +2 more sources

Recent Advances in Dengue Fever Based on Serotypes, Virulence Factors, Prevention, and Treatment: A Comprehensive Review [PDF]

Disease and Diagnosis
Dengue fever, a Flaviviridae viral disease, exhibits various clinical symptoms, such as hemorrhagic fever, and is influenced by multiple factors. This comprehensive review aims to explore different aspects of dengue fever.
Ali Salimi Asl, Narjes Seddighi, Amir Mohammad Barani, Mahla Naderi Nasab, Elham Barahimi   +4 more
doaj   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication [PDF]

Proceedings of the National Academy of Sciences, 2004
The study of the hepatitis C virus (HCV) has been hindered by the lack of in vitro model systems. The recent development of HCV subgenomic RNA replicons has permitted the study of viral RNA replication in cell culture; however, the requirements for efficient replication of replicons in this system are poorly ...
Matthew J, Evans, Charles M, Rice, Stephen P, Goff   +2 more
openaire   +2 more sources

Mediterranean Fin Whales (Balaenoptera physalus) Threatened by Dolphin MorbilliVirus [PDF]

, 2015
During 2011-2013, dolphin morbillivirus was molecularly identified in 4 stranded fin whales from the Mediterranean Sea. Nucleoprotein, phosphoprotein, and hemagglutinin gene sequences of the identified strain were highly homologous with those of a ...
BEFFAGNA, GIORGIA, Casalone, Cristina, CENTELLEGHE, CINZIA, Cocumelli, Cristiano, Denurra, Daniele, Di Francesco, Cristina Esmeralda, Di Guardo, Giovanni, MAZZARIOL, SANDRO, Pautasso, Alessandra, Pintore, Antonio, Povinelli, Michele, Terracciano, Giuliana   +11 more
core   +3 more sources