Results 101 to 110 of about 4,116,626 (248)

Structure of schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism of genome encapsidation [PDF]

, 2013
Schmallenberg virus (SBV), a newly emerged orthobunyavirus (family <i>Bunyaviridae</i>), has spread rapidly across Europe and has caused congenital abnormalities in the offspring of cattle, sheep, and goats.
Li, P., Dong, H., Li, Ping, Elliott, Richard M, Dong, Changjiang, Dong, C., Dong, Haohao, Elliott, Richard M., Elliott, R.M.   +8 more
core   +1 more source

SARS-CoV-2 Nucleocapsid Assembly Inhibitors: Repurposing Antiviral and Antimicrobial Drugs Targeting Nucleocapsid-RNA Interaction [PDF]

, 2020
SARS-CoV-2 pandemic has become a serious concern due to high transmission of this virus and unavailability of any definitive drugs yet in clinics. While novel antivirals are under investigation stage, scientists are also rigorously trying to use drug ...
UPASANA, RAY, Debica, Mukherjee
core   +1 more source

Differences in SARS‐CoV‐2 Antigen Persistence in Individuals With Systemic Autoimmune Rheumatic Diseases Compared to the General Population: A RECOVER‐Adult Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective Individuals with systemic autoimmune rheumatic diseases (SARDs) are at risk for worse acute and post–acute COVID‐19 outcomes, though whether individuals with SARDs have longer persistence of viral antigens after COVID‐19 has not been studied.
Naomi J. Patel, Zoe Swank, Jiaqi Wang, Xiaosong Wang, Lauren A. O'Keeffe, Madison Negron, Liya S. Getachew, Louise L. Hansen, Grace Qian, Alene A. Saavedra, Kevin T. Mueller, Natalie A. Davis, Kathleen M. M. Vanni, Sandria Savage, Julie S. Lam, Zachary S. Wallace, David R. Walt, Jeffrey A. Sparks, on behalf of RECOVER‐Adult   +18 more
wiley   +1 more source

Preliminary Analysis of Vital Proteins of the Human Respiratory Syncytial Virus [PDF]

, 2010
Human Respiratory Syncytial Virus infects the vast majority of children under the age of two and reoccurs in adulthood. It is a serious global problem as severe infection and death can result in the very young or very old and in immunocompromised people.
BACHE, HELEN,CLARE
core  

Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly

Nature Communications
Baculoviruses are insect-infecting pathogens with wide applications as biological pesticides, in vitro protein production vehicles and gene therapy tools.
Friederike M. C. Benning, Simon Jenni, Coby Y. Garcia, Tran H. Nguyen, Xuewu Zhang, Luke H. Chao   +5 more
doaj   +1 more source

Nucleocapsid Protein of SARS-CoV-2 Upregulates RANTES Expression in A172 Glioblastoma Cells

Molecules
SARS-CoV-2, the pathogenic virus that induces COVID-19 disease, contains four structural proteins in its virion. The nucleocapsid (N) protein is one of the four structural proteins that play a crucial role in the assembly of viral RNA into ...
Bakhytgul Gadilgereyeva, Zhanar Kunushpayeva, Mira Abdrakhmanova, Aizere Khassenova, Nail Minigulov, Timo Burster, Olena Filchakova   +6 more
doaj   +1 more source

A novel amino acid site of N protein could affect the PRRSV-2 replication by regulating the viral RNA transcription

BMC Veterinary Research, 2022
Background Finding the key amino acid sites that could affect viral biological properties or protein functions has always been a topic of substantial interest in virology.
Hua Deng, Ning Xin, Fancong Zeng, Feng Wen, Heyou Yi, Chunquan Ma, Shujian Huang, Guihong Zhang, Yao Chen   +8 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Au(iii) compounds as HIV nucleocapsid protein (NCp7)–nucleic acid antagonists [PDF]

, 2017
The HIV nucleocapsid NCp7-SL2 RNA interaction is interrupted in the presence of a formally substitution-inert gold(dien)-nucleobase/N-heterocycle AuN4 compound where the N-heterocycle serves the dual purposes of a template for "non-covalent" molecular ...
Fabris, Daniele, Spell, Sarah R, Mangrum, John B, Peterson, Erica J, Ptak, Roger, Farrell, Nicholas P   +5 more
core   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source