Results 111 to 120 of about 4,116,626 (248)

LDHB suppresses the PDCoV proliferation by targeting viral nucleocapsid protein for autophagic degradation

Microbiology Spectrum
ABSTRACT Porcine deltacoronavirus (PDCoV) is a newly identified enteric coronavirus that causes serious diarrhea and vomiting in pigs, leading to substantial economic losses globally. Studying the molecular interactions between virus and host proteins is crucial for developing new anti-PDCoV strategies.
Xiaohan Wu, Shijin Lan, Ying Wang, Shixing Yang, Quan Shen, Xiaochun Wang, Yuwei Liu, Hongfeng Yang, Likai Ji, Wen Zhang   +9 more
openaire   +3 more sources

Nucleocapsid independent assembly of coronavirus like particles by co expression of viral envelope protein genes

, 1996
Budding of enveloped viruses has been shown to be driven by interactions between a nucleocapsid and a proteolipid membrane. By contrast, we here describe the assembly of viral envelopes independent of a nucleocapsid.
Rottier, P J, Rossen, J W, Horzinek, M.C., Rottier, P.J.M., Vennema, H, Horzinek, M C, Vennema, H., Rossen, J.W.A., Voorhout, W F, Godeke, G.-J., Voorhout, W.F., Opstelten, D.J., Rossen, J W; id_orcid, Godeke, G J, Opstelten, D J   +14 more
core   +1 more source

Endogenous Viral Etiology of Prion Diseases [PDF]

, 2009
Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of incurable neurodegenerative disorders, including Kuru and Creutzfeldt-Jakob disease in humans, “mad cow” disease in cattle, and scrapie in sheep. This paper
Claudiu I. Bandea
core  

Elucidating the Interacting Domains of Chandipura Virus Nucleocapsid Protein

Advances in Virology, 2013
The nucleocapsid (N) protein of Chandipura virus (CHPV) plays a crucial role in viral life cycle, besides being an important structural component of the virion through proper organization of its interactions with other viral proteins.
Kapila Kumar, Sreejith Rajasekharan, Sahil Gulati, Jyoti Rana, Reema Gabrani, Chakresh K. Jain, Amita Gupta, Vijay K. Chaudhary, Sanjay Gupta   +8 more
doaj   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source

Elucidation of functional domains of Chandipura virus Nucleocapsid protein involved in oligomerization and RNA binding: Implication in viral genome encapsidation

, 2010
Chandipura virus, a member of the vesiculovirus genera, has been recently recognized as an emerging human pathogen. Previously, we have shown that Chandipura virus Nucleocapsid protein N is capable of binding to both specific viral leader RNA as well as ...
Raja Bhattacharya, Dhrubajyoti Chattopadhyay, Basu, Atanu, Tridib Ganguly, Arindam Mondal, Subhradip Mukhopadhyay, Mukhopadhyay, Subhradip, Bhattacharya, Raja, Ganguly, Tridib, Chattopadhyay, Dhrubajyoti, Mondal, Arindam, Atanu Basu, Basak, Soumen, Soumen Basak   +13 more
core   +1 more source

Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]

, 2011
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F., Palmarini, M., Ratinier Maxime, Ratinier, Maxime, Golder, Matthew, Nunes, S.F., Alessia Armezzani, Sandro Filipe Nunes, Kathryn Allan, Allan Kathryn, Allan, K., Rixon, Frazer, Golder, M., Allan, Kathryn, Nunes Sandro Filipe, Frazer Rixon, Bayoumy, Amr, Shaw, A., Matthew Golder, Franzoni, G., Caporale Marco, Giulia Franzoni, Golder Matthew, Nunes, Sandro Filipe, Bayoumy Amr, Shaw, Andrew, Amr Bayoumy, Palmarini Massimo, Armezzani, A., Shaw Andrew, Palmarini, Massimo, Ratinier, M., Armezzani, Alessia, Franzoni Giulia, Franzoni, Giulia, Maxime Ratinier, Andrew Shaw, Rixon Frazer, Marco Caporale, Massimo Palmarini, Armezzani Alessia, Bayoumy, A., Caporale, Marco, Caporale, M.   +43 more
core   +1 more source

Decoding sequence recognition code of nucleic acid‐binding proteins of human‐infecting DNA viruses

iMeta, EarlyView.
Human‐infecting DNA viruses remain major health threats, yet the DNA‐recognition mechanisms of their nucleic acid‐binding proteins (NBPs) are poorly understood. Here, we systematically profiled 103 viral NBPs from human‐infecting DNA viruses, with three NBPs from non‐human‐infecting DNA viruses as controls, using high‐throughput screening.
Meifang Tang, Shifei Yang, Haiqian Ma, Ruoying Guo, Jie Chen, Hui Zhang, Jinghan Zhang, Wei Sun, Yun Wei, Ligang Fan, Jian Yan   +10 more
wiley   +1 more source

An insight into SARS-CoV-2 membrane protein interaction with spike, envelope, and nucleocapsid proteins

, 2021
Intraviral protein–protein interactions are crucial for replication, pathogenicity, and viral assembly. Among these, virus assembly is a critical step as it regulates the arrangements of viral structural proteins and helps in the encapsulation of genomic
Prateek Kumar (802333), Amit Kumar (81180), Neha Garg (194824), Rajanish Giri (6115907)   +3 more
core   +1 more source