Results 101 to 110 of about 597,555 (197)
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling
Dishevelled (Dvl) is a key regulator of Wnt signaling both in the canonical and non-canonical pathways. Here we report the identification of a regulatory domain of ubiquitination (RDU) in the C-terminus of Dvl.
Jung, H +10 more
core +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus +7 more
wiley +1 more source
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao +14 more
wiley +1 more source
Viral hepatitis surveillance report : United States, 2019 [PDF]
The Centers for Disease Control and Prevention (CDC) collects, analyzes, and disseminates viral hepatitis surveillance data. Each week, staff at health departments submit case reports of viral hepatitis to CDC through the National Notifiable Diseases ...
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Biotechnology, viral oncogenesis and jaagsiekte [PDF]
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.A brief description is given of the discovery of ...
core +1 more source
Objectives To clarify the association between active Epstein–Barr virus (EBV) infection and the risk of multiple myeloma (MM), given longstanding uncertainty regarding EBV’s etiologic contribution to plasma cell malignancies.Methods A meta-analysis was ...
Zhimei Wu, Huiye Yang, Yongrong Lai
doaj +1 more source
Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao +11 more
wiley +1 more source
Putting viral hepatitis on the map [PDF]
The DVH-funded FOA PS08-801 was intended to integrate primary and secondary viral hepatitis prevention services, education and counseling into health care settings and programs that serve adults at risk for viral hepatitis.
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