Results 81 to 90 of about 597,555 (197)
Immunological Heterogeneity in Gastric Cancer: Context‐Dependent Role of CD8+ T Cells
CD8+ T cell infiltration in gastric cancer shows subtype‐dependent prognostic and predictive significance across TCGA molecular subtypes. Its clinical value is context‐dependent and requires integrated immune profiling to guide modern chemoimmunotherapy strategies.
Xiaofei Sun +3 more
wiley +1 more source
This blog is designed to be the online platform for the ERC Starting Grant Project "Going Viral. Music and Emotions during Pandemics (1679-1919)" (PI Prof. Dr. Marie Louise Herzfeld-Schild).
Marie Louise Herzfeld-Schild
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Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang +6 more
wiley +1 more source
Viral hepatitis surveillance United States, 2018 [PDF]
Viral Hepatitis Surveillance \u2014 United States, 2018 is published by the Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC), U.S.
core +2 more sources
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil +2 more
wiley +1 more source
Adenovirus early E4 genes in viral oncogenesis
Previous investigations into potential transforming activities of adenovirus (Ad) early genes were largely overshadowed by the more obvious roles of EIA and E1B products.
Dobner, Thomas, Täuber, Birgitt
core +1 more source
Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection [PDF]
Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single ...
Ruiz, L +9 more
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This perspective examines the potential oncogenic mechanisms of SARS-CoV-2 through comparative analysis with established cancer-causing viruses, integrating classical virological approaches with artificial intelligence (AI)-driven analysis.
Thorsten Rudroff
doaj +1 more source
Merkel cell carcinoma: an updated guide for pathologists
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley +1 more source
ABSTRACT Persistent unilateral otalgia, especially when refractory to treatment and associated with cranial nerve signs, should prompt early imaging and nasopharyngeal evaluation to avoid delayed diagnosis of aggressive malignancies such as Burkitt lymphoma.
Sultaneh Haddad +9 more
wiley +1 more source

