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The viral oncogenesis of COVID-19 and its impact on cancer progression, long-term risks, treatment complexities, and research strategies [PDF]
Exploration of MedicineThe interaction between cancer and coronavirus disease 2019 (COVID-19) poses significant challenges, particularly for immunocompromised individuals who are at heightened risk for acute infections and long-term complications.
Moawiah M Naffaa, Ola A Al-Ewaidat
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iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
HTLV-1 Alters T Cells for Viral Persistence and Transmission
Frontiers in Microbiology, 2018 Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory diseases.
Azusa Tanaka +2 more
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WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen +4 more
wiley +1 more source
Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses
Frontiers in Microbiology, 2018 Infections with cutaneous papillomaviruses have been linked to cutaneous squamous cell carcinomas that arise in patients who suffer from a rare genetic disorder, epidermodysplasia verruciformis, or those who have experienced long-term, systemic ...
Jordan M. Meyers +5 more
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Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
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, 2006 In recent years, investigations with different tumour virus models gave important contributions and led to the acquisition of significant advances in many biomedical fields. It is worth reminding, as examples, that DNA tumour viruses such as SV40 allowed
TOGNON, Mauro
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Viruses, 2014 Twenty years ago, Kaposi’s sarcoma (KS) was the oncologic counterpart to Winston Churchill’s Russia: a riddle, wrapped in a mystery, inside an enigma.
Yuan Chang, Patrick Moore
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Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Viral and Cellular MicroRNAs in Regulation of EBV Latency and Oncogenesis [PDF]
, 2017 Epstein-Barr virus (EBV), an oncogenic virus that ubiquitously establishes life-long persistence in humans, encodes viral miRNAs in two clusters, BHRF1 and BART.
Ning, Shunbin, Wang, Ling
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