Results 241 to 250 of about 1,219,846 (287)

Respiratory enterovirus D68: virology, clinical surveillance, host-pathogen interactions, and therapeutic prospects. [PDF]

Front Cell Infect Microbiol
Gui Y, Han B, Wei J, Sun D, Zhou L, Yuan S, Xie W, Feng H.   +7 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Viral Proteases

Chemical Reviews, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Liang Tong
exaly   +4 more sources

Antiviral drug discovery targeting to viral proteases. [PDF]

Current Pharmaceutical Design, 2006
Proteases fulfill multiple roles in health and disease, and considerable interest has been expressed in the design and development of synthetic inhibitors of disease-related proteases. Virus-encoded proteases have been shown to be involved in the replication of many viruses.
J. T. Hsu, Hsiang-Ching Wang, Guang-Wu Chen, S. Shih   +3 more
semanticscholar   +4 more sources

Viral proteases as targets for drug design.

Current Pharmaceutical Design, 2012
In order to productively infect a host, viruses must enter the cell and force host cell replication mechanisms to produce new infectious virus particles. The success of this process unfortunately results in disease progression and, in the case of infection with many viral species, may cause mortality.
Marcin Skoreński, M. Sieńczyk
semanticscholar   +3 more sources

Inhibiting viral proteases: challenges and opportunities.

Peptide Science, 2002
AbstractInhibitor design against viral targets must take into account the peculiar characteristics of viral biology—in particular, the plasticity of their replicative machinery. This includes maturational cleavage of the polyprotein, which is mediated by virally encoded proteases.
E. Bianchi, A. Pessi
semanticscholar   +3 more sources

Viral proteases as targets for antivirals drugs

The Enzymes
The biochemical machinery of all viruses comprises enzymes able to cleave polyproteins formed after the transcription of the viral genetic material, which belong to the protease class. Viral proteases known so far belong to the aspartic, serine and cysteine protease classes, with no viral metalloprotease described to date. The tridimensional structure,
Luigi, Pisano, Claudiu T, Supuran
exaly   +3 more sources

Viral Proteases

Encyclopedia of Molecular Pharmacology, 2021
Marcin Skoreński, Renata Grzywa, M. Sieńczyk   +2 more
semanticscholar   +2 more sources

Hepatitis C Viral Proteases And Inhibitors

2006
527. Reiser M, Hinrichsen H, Benhamou Y, Reesink HW, Wedemeyer H, Avendano C, Riba N, Yong CL, Nehmiz G, Steinmann GG, 2005, Antiviral efficacy of NS3-serine protease inhibitor BILN-2061 in patients with chronic genotype 2 and 3 hepatitis C. Hepatology. 41: 832-835. Santolini E, Pacini L, Fipaldini C, Migliaccio G, La Monica N, 1995, The NS2 protein of
Atul Agarwal
exaly   +2 more sources

Viral Proteases and Antiviral Protease Inhibitor Therapy

, 2009
U. Lendeckel, N. Hooper
semanticscholar   +2 more sources

Colorimetric Cotton Swab for Viral Protease Detection

Analytical Chemistry, 2022
Reporting the activity of a specific viral protease remains an acute need for rapid point-of-care detection strategies that can distinguish active infection from a resolved infection. In this work, we present a simple colorimetric approach for reporting the activity of a specific viral protease through direct color conversion on a cotton swab, which ...
Ranit Dutta, Sparsh Makhaik, Peiyao Zhao, Kristalle G. Cruz, Kwang-Won Park, Hongxu Liu, Trisha L. Andrew, Jeanne A. Hardy, S. Thayumanavan   +8 more
openaire   +2 more sources