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Viruses and viral proteins [PDF]

open access: yesIUCrJ, 2014
For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution.
Nuria Verdaguer   +2 more
doaj   +6 more sources

A Comprehensive View on the Host Factors and Viral Proteins Associated With Porcine Epidemic Diarrhea Virus Infection

open access: yesFrontiers in Microbiology, 2021
Porcine epidemic diarrhea virus (PEDV), a coronavirus pathogen of the pig intestinal tract, can cause fatal watery diarrhea in piglets, thereby causing huge economic losses to swine industries around the world.
Yi Hu   +4 more
doaj   +2 more sources

KEGG tools for classification and analysis of viral proteins. [PDF]

open access: yesProtein Sci, 2023
The KEGG database and analysis tools (https://www.kegg.jp) have been developed mostly for understanding genes and genomes of cellular organisms. The KO (KEGG Orthology) dataset, which is a collection of functional orthologs, plays the role of linking ...
Jin Z, Sato Y, Kawashima M, Kanehisa M.
europepmc   +2 more sources

Membrane activity of viral proteins. [PDF]

open access: yesBiophys Rev, 2023
COVID-19 infection, caused by the SARS-CoV-2 coronavirus, has led to the largest pandemic since the Spanish flu in 1918. In view of this, the development of vaccines and antiviral drugs that can stop the spread of this infection has become an acute issue. Currently, in the search for antiviral drugs against COVID-19, much attention is paid to the study
Denieva Z.
europepmc   +3 more sources

Evolutionary‐Distinct Viral Proteins Subvert Rice Broad‐Spectrum Antiviral Immunity Mediated by the RAV15‐MYC2 Module [PDF]

open access: yesAdvanced Science
A variety of plant viruses employ different virulence strategies to achieve successful infection, resulting in abnormal plant development. However, the common pathogenicity of distinct viruses has rarely been studied.
Hehong Zhang   +10 more
doaj   +2 more sources

Prokaryotic innate immunity through pattern recognition of conserved viral proteins

open access: yesScience, 2022
Many organisms have evolved specialized immune pattern-recognition receptors, including nucleotide-binding oligomerization domain–like receptors (NLRs) of the STAND superfamily that are ubiquitous in plants, animals, and fungi. Although the roles of NLRs
L. Gao   +6 more
semanticscholar   +1 more source

Glycosylation of viral proteins: Implication in virus–host interaction and virulence

open access: yesVirulence, 2022
Glycans are among the most important cell molecular components. However, given their structural diversity, their functions have not been fully explored. Glycosylation is a vital post-translational modification for various proteins.
Tingting Feng   +6 more
semanticscholar   +1 more source

Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses

open access: yesFrontiers in Immunology, 2021
Hijacking host ubiquitin pathways is essential for the replication of diverse viruses. However, the role of deubiquitinating enzymes (DUBs) in the interplay between viruses and the host is poorly characterized. Here, we demonstrate that specific DUBs are
Wenying Gao   +12 more
doaj   +1 more source

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