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Evolutionary‐Distinct Viral Proteins Subvert Rice Broad‐Spectrum Antiviral Immunity Mediated by the RAV15‐MYC2 Module [PDF]
A variety of plant viruses employ different virulence strategies to achieve successful infection, resulting in abnormal plant development. However, the common pathogenicity of distinct viruses has rarely been studied.
Hehong Zhang+10 more
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Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses
Hijacking host ubiquitin pathways is essential for the replication of diverse viruses. However, the role of deubiquitinating enzymes (DUBs) in the interplay between viruses and the host is poorly characterized. Here, we demonstrate that specific DUBs are
Wenying Gao+12 more
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Automatic analysis of colocalizing biological structures in multi-channel fluorescence microscopy images is an important task to quantify and understand biological processes at high spatial-temporal resolution.
Christian Ritter+5 more
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To explore the sequence context-dependent nature of the human immunodeficiency virus type 1 (HIV-1) protease’s specificity and to provide a rationale for viral mutagenesis to study the potential role of the nucleocapsid (NC) processing in HIV-1 ...
János András Mótyán+3 more
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The ongoing pandemic caused by the novel coronavirus (SARS-CoV-2) has led to more than 445 million infections and the underlying disease, COVID-19, resulted in more than 6 million deaths worldwide.
Franziska Ramm+11 more
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Mimicry between respiratory virus proteins and some human immune proteins
A comparative analysis on search for amino acid sequences in viral proteins causing respiratory infections (or respiratory infections syndrome) homologous to amino acid sequences from some human immune proteins was performed.
I. N. Zhilinskaya
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Steve Oroszlan: A Personal Perspective
My memories of Steve go back over 50 years. While precise dates are no longer in my memory bank, circumstances and emotions remain alive and easy to recall.
Raymond Gilden
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I was fortunate to be associated with the lab of Stephen Oroszlan at the US National Cancer Institute from ~1982 until his conversion to Emeritus status in 1995.
Alan Rein
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Mimicry between proteins of human and avian influenza viruses and host immune system proteins
Viral infection can lead to dangerous and severe manifestations associated with immunosuppression and a cytokine storm. The last is typical for influenza A virus infection of H1N1 subtype, when the level of cytokines in the peripheral blood is ...
Irina N. Zhilinskaya+2 more
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Novel and efficient strategies need to be developed to interfere with the SARS-CoV-2 virus. One of the most promising pharmaceutical targets is the nucleocapsid protein (N), responsible for genomic RNA packaging.
Marco Schiavina+4 more
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