Results 1 to 10 of about 6,360,309 (211)

Viral hijacking of cellular metabolism [PDF]

open access: yesBMC Biology, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Shivani K. Thaker   +2 more
semanticscholar   +3 more sources

Prokaryotic innate immunity through pattern recognition of conserved viral proteins

open access: yesScience, 2022
Many organisms have evolved specialized immune pattern-recognition receptors, including nucleotide-binding oligomerization domain–like receptors (NLRs) of the STAND superfamily that are ubiquitous in plants, animals, and fungi. Although the roles of NLRs
L. Gao   +6 more
semanticscholar   +1 more source

Glycosylation of viral proteins: Implication in virus–host interaction and virulence

open access: yesVirulence, 2022
Glycans are among the most important cell molecular components. However, given their structural diversity, their functions have not been fully explored. Glycosylation is a vital post-translational modification for various proteins.
Tingting Feng   +6 more
semanticscholar   +1 more source

SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms

open access: yesPLoS ONE, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating global pandemic, infecting over 43 million people and claiming over 1 million lives, with these numbers increasing daily.
Christine Vazquez   +7 more
semanticscholar   +1 more source

Genome-wide analysis of protein–protein interactions and involvement of viral proteins in SARS-CoV-2 replication

open access: yesCell & Bioscience, 2021
Analysis of viral protein–protein interactions is an essential step to uncover the viral protein functions and the molecular mechanism for the assembly of a viral protein complex. We employed a mammalian two-hybrid system to screen all the viral proteins
Yiling Jiang   +12 more
semanticscholar   +1 more source

A Comprehensive View on the Host Factors and Viral Proteins Associated With Porcine Epidemic Diarrhea Virus Infection

open access: yesFrontiers in Microbiology, 2021
Porcine epidemic diarrhea virus (PEDV), a coronavirus pathogen of the pig intestinal tract, can cause fatal watery diarrhea in piglets, thereby causing huge economic losses to swine industries around the world.
Yi Hu   +3 more
semanticscholar   +1 more source

Defective HIV-1 proviruses produce viral proteins

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance In HIV-infected patients on combination antiretroviral therapy (cART), greater than 95% of proviruses in the peripheral blood are “defective.” Historically, these defective proviruses have been thought to be dead-end products with no real ...
H. Imamichi   +11 more
semanticscholar   +1 more source

SARS-CoV-2 Accessory Proteins in Viral Pathogenesis: Knowns and Unknowns

open access: yesFrontiers in Immunology, 2021
There are still many unanswered questions concerning viral SARS-CoV-2 pathogenesis in COVID-19. Accessory proteins in SARS-CoV-2 consist of eleven viral proteins whose roles during infection are still not completely understood.
Natalia Redondo   +3 more
semanticscholar   +1 more source

Engineering multiple levels of specificity in an RNA viral vector [PDF]

open access: yes, 2020
Synthetic molecular circuits could provide powerful therapeutic capabilities, but delivering them to specific cell types and controlling them remains challenging.
Chong, Lucy S.   +4 more
core   +1 more source

Programming Dynamic Assembly of Viral Proteins with DNA Origami.

open access: yesJournal of the American Chemical Society, 2020
Biomolecular assembly in biological systems is typically a complex dynamic process regulated by the exchange of molecular information between biomolecules such as proteins and nucleic acids.
Kun Zhou   +4 more
semanticscholar   +1 more source

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