Results 91 to 100 of about 438,262 (317)

Replication of Avian Sarcoma Virus In Vivo Requires an Interaction between the Viral RNA and the TψC Loop of the tRNA ^Trp Primer [PDF]

, 2002
Shannon R. Morris, Michael L. Johnson, Ed Stavnezer, Jonathan Leis   +3 more
openalex   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

FOLR1-induced folate deficiency reduces viral replication via modulating APOBEC3 family expression

, 2023
Jing Wu, Yajing Han, Ruining Lyu, Fang Zhang, Na Jiang, Hongji Tao, Qiao You, Rui Zhang, Yuan Meng, Waqas Nawaz, Deyan Chen, Zhiwei Wu   +11 more
openalex   +1 more source

Selectively replicating viral vectors [PDF]

Cancer Gene Therapy, 2002
John, Nemunaitis, Jeffrey, Edelman
openaire   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Macroautophagy—friend or foe of viral replication? [PDF]

EMBO reports, 2013
Autophagy can either degrade pathogens or promote their replication. Both effects have been reported for Chikungunya virus and a recent study in EMBO reports solves this controversy, whilst indicating how to improve mouse models of the infection.
openaire   +3 more sources

Micropleated Nanofibrous Filters for High‐Efficiency Submicron Aerosol Filtration: A Comparative Study with Chemical, Biological, Radiological, and Nuclear Gas Mask Filters

Advanced Engineering Materials, EarlyView.
This study presents micropleated filters manufactured by needleless electrospinning. Nanofibers are deposited onto uniaxially pre‐stretched substrates that contract upon release, forming densely packed micropleats. This architecture increases effective surface area without enlarging the filter size, achieving quality factors comparable to those of ...
Aleksandr Fadeev, Kevin Crown, Sean Kinahan, Gabriel Lucero, Hayden Stromsodt, Svetlana Romanova, Yury Salkovskiy   +6 more
wiley   +1 more source

Rice stripe mosaic virus encoded phosphoprotein forms viral factory-like granules and is crucial for viral replication

Phytopathology Research
Viral proteins can aggregate into granules within host cells, known as viral factories, or viroplasms, which play a pivotal role in facilitating viral replication and shielding the viral genome from cellular defense mechanisms.
Zhiyi Wang, Jingyi Zhang, Xinyue Song, Siping Chen, Xue Cao, Xin Yang, Guohui Zhou, Tong Zhang   +7 more
doaj   +1 more source

Open Reading Frame 8a of the Human Severe Acute Respiratory Syndrome Coronavirus Not Only Promotes Viral Replication but Also Induces Apoptosis [PDF]

, 2007
Chia‐Yen Chen, Yueh‐Hsin Ping, Hsin‐Chen Lee, Kuan-Hsuan Chen, Yuan-Ming Lee, Yu-Juin Chan, Te-Cheng Lien, Tjin‐Shing Jap, Chi-Hung Lin, Lung‐Sen Kao, Yi‐Ming Arthur Chen   +10 more
openalex   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source