Results 91 to 100 of about 366,840 (272)

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

G-quadruplex as an essential structural element in cytomegalovirus replication origin

open access: yesNature Communications
G-quadruplex (G4) structures are found in eukaryotic cell replication origins, but their role in origin function remains unclear. In this study G4 motifs are found in the lytic DNA replication origin (oriLyt) of human cytomegalovirus (HCMV) and ...
Daegyu Park   +7 more
doaj   +1 more source

Narrow escape to small windows on a small ball modeling the viral entry into the cell nucleus [PDF]

open access: yesarXiv, 2016
A certain class of viruses replicates inside a cell if they can enter the nucleus through one of many small target pores, before being permanently trapped or degraded. We adopt for viral motion a switching stochastic process model and we estimate here the probability and the conditional mean first passage time for a viral particle to attain alive the ...
arxiv  

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

Efficient HIV-1 in vitro reverse transcription: optimal capsid stability is required

open access: yesSignal Transduction and Targeted Therapy, 2021
Ryan C. Burdick, Vinay K. Pathak
doaj   +1 more source

Human Cytomegalovirus UL34 Early and late Proteins Are Essential for Viral Replication

open access: yesViruses, 2014
UL34 is one of the ~50 genes of human cytomegalovirus (HCMV) required for replication in cell culture in human fibroblasts. UL34 encodes highly related early (UL34a) and late (UL34b) proteins that are virtually identical, with the early protein ...
Rico Rana, Bonita J. Biegalke
doaj   +1 more source

Stress Response of Aspergillus niger Spores to Copper Surfaces and the Implications for Antifungal Surface Functionalization

open access: yesAdvanced Materials Interfaces, EarlyView.
This study investigates the antifungal efficacy of ultrashort pulsed laser‐induced periodic surface structures (USP‐DLIP) on copper, brass, and steel surfaces. Using Aspergillus niger as a model, the research highlights a 99% reduction in spore viability on 9 µm structured copper surfaces due to enhanced copper ion release. Scanning electron microscopy
Stella Marie Timofeev   +10 more
wiley   +1 more source

Prostaglandin A1 triggers Mayaro virus inhibition and heat shock protein 70 expression in an epithelial cell model

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: The Mayaro virus (MAYV), which is an arbovirus closely related to the Chikungunya virus, causes a dengue-like acute illness that is endemic to Central and South America.
Lucio Ayres Caldas   +2 more
doaj   +1 more source

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