Results 151 to 160 of about 366,840 (272)
Sequences in the polyomavirus DNA regulatory region involved in viral DNA replication and early gene expression [PDF]
Lisa A. Dailey, Claudio Basilico
openalex +1 more source
Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen+9 more
wiley +1 more source
Regulatory function of simian virus 40 DNA replication for late viral gene expression.
A. Graessmann+2 more
openalex +1 more source
Cellular and viral control of the initiation of DNA replication [PDF]
James M. Roberts, Gennaro D’Urso
openalex +1 more source
Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen+16 more
wiley +1 more source
Regulation of viral replication by host restriction factors. [PDF]
Lin Y, Zhu Y, Jing L, Lei X, Xie Z.
europepmc +1 more source
SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi+11 more
wiley +1 more source
Host cytoskeleton and membrane network remodeling in the regulation of viral replication. [PDF]
Gao X, Chen X, Yu L, Zhao S, Jiu Y.
europepmc +1 more source
This study reveals the tumor‐suppressive role of TRIM38 in colorectal cancer (CRC). TRIM38 is downregulated through DNA hypermethylation and correlates with unfavorable clinical features and poor prognosis. Mechanistically, TRIM38 inhibits CRC progression by promoting K48‐linked ubiquitination of CCT6A, leading to the destabilization of c‐Myc.
Yue Zhang+10 more
wiley +1 more source