Results 281 to 290 of about 617,233 (366)

Absence of Viral Replication Is Associated With Improved Outcome in Anti-HCV-Positive Patients With Hepatocellular Carcinoma. [PDF]

Liver Int
Giannini EG, Pasta A, Plaz Torres MC, Pieri G, Cabibbo G, Sangiovanni A, Piscaglia F, Campani C, Missale G, Vidili G, Ghittoni G, Pelizzaro F, Foschi FG, Morisco F, Santi V, Svegliati-Baroni G, Azzaroli F, Saitta C, Brunetto MR, Sacco R, Ponziani FR, Boninsegna S, Nardone G, Martini A, Mega A, Sacerdoti D, Magalotti D, Vitale A, Bucci L, Trevisani F, Italian Liver Cancer (ITA.LI.CA) group.   +30 more
europepmc   +1 more source

Organization of the Proteostasis Network of Membraneless Organelles

Advanced Science, EarlyView.
A comprehensive mapping of the proteostasis network (PN) across membraneless organelles (MLOs) reveals how central PN components coordinate MLO regulation. The analysis uncovers principles of specificity and promiscuity within the PN. The findings suggest that HSP70 chaperones act as generic MLO regulators, while client specific HSP70 co‐chaperones may
Christine M. Lim, Yuqi Bian, Alicia González Díaz, Frank Pun, Alex Zhavoronkov, Richard I. Morimoto, Michele Vendruscolo   +6 more
wiley   +1 more source

MARCH8 promotes the proteasomal degradation of foot-and-mouth disease virus VP1, VP2, and VP3 to negatively regulate viral replication. [PDF]

Vet Res
Yin M, Li X, Zhang M, Zhao Q, Wang H, Zhang H, Lu Z, Qian P.   +7 more
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Macrophages, mycobacteria and HIV: the role of cytokines in determining mycobacterial virulence and regulating viral replication

, 1992
Robert S. Wallis, Jerrold J. Ellner, Hiroe Shiratsuchi   +2 more
openalex   +1 more source

Direct infection of CD34+ progenitor cells by human cytomegalovirus: evidence for inhibition of hematopoiesis and viral replication [PDF]

, 1996
M Movassagh, Joël Gozlan, Brigitte Sénéchal, Claude Baillou, JC Petit, FM Lemoine   +5 more
openalex   +1 more source

Novel strand-specific qPCR assay elucidates differences in viral replication kinetics between different strains of avian reovirus. [PDF]

Microbiol Spectr
Harrell TL, Alvarez-Narvaez S, Read QD, Conrad SJ.   +3 more
europepmc   +1 more source

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Advanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu   +22 more
wiley   +1 more source

A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition.

, 1992
Carl Wild, Terrence G. Oas, Charlene McDanal, Dani P. Bolognesi, Thomas J. Matthews   +4 more
openalex   +1 more source

Foot-and-mouth disease virus activates glycolysis and hijacks HK2 to inhibit innate immunity and promote viral replication. [PDF]

Vet Res
Chen W, Wang X, Li X, Wang W, Huang Y, Qin Y, Liu P, Wu K, Li B, He Y, Zeng S, Yi L, Wang L, Zhao M, Ding H, Fan S, Li Z, Chen J.   +17 more
europepmc   +1 more source