Results 281 to 290 of about 2,155,361 (380)

Herpesviruses mimic zygotic genome activation to promote viral replication. [PDF]

open access: yesNat Commun
Neugebauer E   +17 more
europepmc   +1 more source

Reverse Genetics System Demonstrates that Rotavirus Nonstructural Protein NSP6 Is Not Essential for Viral Replication in Cell Culture

open access: yesJournal of Virology, 2017
S. Komoto   +9 more
semanticscholar   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

open access: yesAdvanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang   +9 more
wiley   +1 more source

Direct infection of CD34+ progenitor cells by human cytomegalovirus: evidence for inhibition of hematopoiesis and viral replication [PDF]

open access: bronze, 1996
M Movassagh   +5 more
openalex   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang   +13 more
wiley   +1 more source

The whole genome analysis of the wild-type and attenuated orf virus reveals that ORF022 facilitates viral replication. [PDF]

open access: yesBMC Genomics
Jing T   +9 more
europepmc   +1 more source

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