Results 51 to 60 of about 1,595,225 (317)
Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection. [PDF]
, 2012 OBJECTIVES: The magnitude of HIV viral rebound following ART cessation has consequences for clinical outcome and onward transmission. We compared plasma viral load (pVL) rebound after stopping ART initiated in primary (PHI) and chronic HIV infection (CHI)
López-Diéguez, María +83 more
core +1 more source
Optimization of AAV vectors to target persistent viral reservoirs [PDF]
Virology Journal, 2021 AbstractGene delivery of antiviral therapeutics to anatomical sites where viruses accumulate and persist is a promising approach for the next generation of antiviral therapies. Recombinant adeno-associated viruses (AAV) are one of the leading vectors for gene therapy applications that deliver gene-editing enzymes, antibodies, and RNA interference ...
Rossana Colón-Thillet +2 more
openaire +3 more sources
Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection [PDF]
, 2002 Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single ...
Ruiz, L +9 more
core +1 more source
The Reservoir of Persistent Human Papillomavirus Infection; Strategies for Elimination Using Anti-Viral Therapies. [PDF]
, 2022 Human Papillomaviruses have co-evolved with their human host, with each of the over 200 known HPV types infecting distinct epithelial niches to cause diverse disease pathologies.
Maki Okamura +6 more
core +2 more sources
Viral Abundance and Diversity of Production Fluids in Oil Reservoirs [PDF]
Microorganisms, 2020 Viruses are widely distributed in various ecosystems and have important impacts on microbial evolution, community structure and function and nutrient cycling in the environment. Viral abundance, diversity and distribution are important for a better understanding of ecosystem functioning and have often been investigated in marine, soil, and other ...
Liangcan Zheng +9 more
openaire +3 more sources
HIV-1 DNA and the HIV-1 Viral Reservoir [PDF]
, 2013 HIV-1 infected resting memory CD4+ T cells are major contributors to the HIV-1 viral reservoir, which is established during early infection, maintaining HIV-1 infection for an individual s life. The effect the timing of therapy initiation has on the size
McBride, Kristin
core +2 more sources
Domestic Animals as Potential Reservoirs of Zoonotic Viral Diseases
Annual Review of Animal Biosciences, 2023 Zoonoses are diseases and infections naturally transmitted between humans and vertebrate animals. Over the years, zoonoses have become increasingly significant threats to global health. They form the dominant group of diseases among the emerging infectious diseases (EID) and currently account for 73% of EID.
Oyewale, Tomori, Daniel O, Oluwayelu
openaire +2 more sources
Mathematical modelling of internal HIV dynamics [PDF]
, 2009 We study a mathematical model for the viral dynamics of HIV in an infected individual in the presence of HAART. The paper starts with a literature review and then formulates the basic mathematical model.
University of Strathclyde (Funder) +4 more
core +1 more source
Journal of Virus Eradication, 2021 HIV-1 is able to persist in the face of potent antiretroviral therapy (ART). A number of strategies are being explored to allow ART-free viral remission or viral eradication.
M. Vignoles +8 more
doaj +1 more source
HTLV-1 as a Model for Virus and Host Coordinated Immunoediting
Frontiers in Immunology, 2019 Immunoediting is a process that occurs in cancer, whereby the immune system acts to initially repress, and subsequently promote the outgrowth of tumor cells through the stages of elimination, equilibrium, and escape.
Talia M. Mota +2 more
doaj +1 more source