Results 21 to 30 of about 858,835 (303)

An Overview of Spike Surface Glycoprotein in Severe Acute Respiratory Syndrome–Coronavirus

open access: yesFrontiers in Molecular Biosciences, 2021
The novel coronavirus originated in December 2019 in Hubei, China. This contagious disease named as COVID-19 resulted in a massive expansion within 6 months by spreading to more than 213 countries.
Muthu Kumaradoss Kathiravan   +5 more
doaj   +1 more source

Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins

open access: yesViruses, 2020
During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2, has already infected over one-hundred thousand people worldwide and has taken more than four thousand lives. However, the swiftly spreading virus also caused
Suhas Srinivasan   +8 more
semanticscholar   +1 more source

Genes of SARS-CoV-2 and emerging variants [PDF]

open access: yesMicrobiology Australia, 2021
The pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is distinctly different from outbreaks caused by other coronaviruses: SARS-CoV andMiddle East respiratory syndrome coronavirus (MERS-CoV).
Ian Macreadie, Sudip Dhakal
doaj  

Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae)

open access: yesВопросы вирусологии, 2023
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva   +3 more
doaj   +1 more source

New Biophysical Approaches Reveal the Dynamics and Mechanics of Type I Viral Fusion Machinery and Their Interplay with Membranes

open access: yesViruses, 2020
Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
doaj   +1 more source

Identification and characterization of coiled-coil motifs across Autographa californica multiple nucleopolyhedrovirus genome

open access: yesHeliyon, 2022
Coiled coils (CCs) are protein structural motifs universally found in proteins and mediate a plethora of biological interactions, and thus their reliable annotation is crucial for studies of protein structure and function. Autographa californica multiple
Jianxiang Qiu   +3 more
doaj   +1 more source

Structural basis of Gabija anti-phage defence and viral immune evasion

open access: yesbioRxiv, 2023
Bacteria encode hundreds of diverse defense systems that protect from viral infection and inhibit phage propagation1–5. Gabija is one of the most prevalent anti-phage defense systems, occurring in >15% of all sequenced bacterial and archaeal genomes1,6,7,
Sadie P. Antine   +8 more
semanticscholar   +1 more source

A viral-human interactome based on structural motif-domain interactions captures the human infectome. [PDF]

open access: yesPLoS ONE, 2013
Protein interactions between a pathogen and its host are fundamental in the establishment of the pathogen and underline the infection mechanism. In the present work, we developed a single predictive model for building a host-viral interactome based on ...
Aldo Segura-Cabrera   +3 more
doaj   +1 more source

Flexible changes to the Heliothis virescens ascovirus 3h (HvAV-3h) virion components affect pathogenicity against different host larvae species

open access: yesMicrobiology Spectrum, 2023
The pathogenicity of a virus to a specific host species is an inerratic and describable ability of a virus to cause infection but is generally shaped by a variety of abiotic and biotic factors.
Huan Yu   +6 more
doaj   +1 more source

MultiBac: from protein complex structures to synthetic viral nanosystems [PDF]

open access: yesBMC Biology, 2017
The MultiBac baculovirus/insect cell expression vector system was conceived as a user-friendly, modular tool-kit for producing multiprotein complexes for structural biology applications. MultiBac has allowed the structure and function of many molecular machines to be elucidated, including previously inaccessible high-value drug targets.
Pelosse, Martin   +5 more
openaire   +5 more sources

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