Results 11 to 20 of about 8,443,463 (315)
Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection [PDF]
, 2002 Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single ...Ruiz, L, Javier Martinez-Picado, Clotet, B, Frost, SDW, Martinez-Picado, J, Lidia Ruiz, Leigh Brown, AJ, Simon D. W. Frost, Bonaventura Clotet, Andrew J. Leigh Brown +9 morecore +1 more sourceDifference of geographic distributions of the Chinese patients with prion diseases in the permanent resident places and referring places
Prion, 2022 Human prion diseases (PrDs) are a group of transmissible neurodegenerative diseases that can be clarified as sporadic, genetic and iatrogenic forms. In this study, we have analysed the time and geographic distributions of 2011 PrD cases diagnosed by ...Kang Xiao, Ming-Fan Pang, Yue-Qiao Zhao, Li-Ping Gao, Yue-Zhang Wu, Yuan Wang, Qi Shi, Xiao-Ping Dong +7 moredoaj +1 more sourceTrends in detectable viral load by calendar year in the Australian HIV observational database [PDF]
, 2011 Background
Recent papers have suggested that expanded combination antiretroviral treatment (cART) through lower viral load may be a strategy to reduce HIV transmission at a population level.Cooper, D.A., Roth, Norman, Templeton, D.J., John Chuah, Templeton, David J., Cooper, D., Hamish McManus, Templeton, D., Ian Woolley, Petoumenos, Kathy, Roth, N., McManus, Hamish, Canavan, P., Woolley, I., Petoumenos, K., Law, M.G., David J Templeton, Chuah, John, Peter Canavan, Mulhall, Brian, Canavan, Peter, Roth, Norm, Cooper, David A., Law, Matthew G., McManus, H., Kathy Petoumenos, Australian HIV Observational Database (AHOD).,, David A Cooper, Matthew G Law, Nolan, D., Templeton, David, null null, Law, M., Brian Mulhall, Norm Roth, Mulhall, B., Cooper, David, Woolley, Ian, Chuah, J., Law, Matthew +39 morecore +1 more sourcePlasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection. [PDF]
, 2012 OBJECTIVES: The magnitude of HIV viral rebound following ART cessation has consequences for clinical outcome and onward transmission. We compared plasma viral load (pVL) rebound after stopping ART initiated in primary (PHI) and chronic HIV infection (CHI)López-Diéguez, María, Babiker, A, Myra McClure (309188), Porter, Kholoud, Jonathan Weber (59115), Phillips, R, Pedersen, Court, Giuseppe Tambussi (237799), Jason F Okulicz (16174841), Weber, Jonathan, Tambussi, G, Weber, J, Hamlyn Elizabeth, Miró Meda, José M. (José María), 1956-, García, M. T., Abdel Babiker (225813), Hamlyn, E, Schechter, M, Pedersen Court, Court Pedersen (38784), Hamlyn, Elizabeth, Jason F Okulicz, Elizabeth Hamlyn (309179), Cooper David A., Manzardo, Christian, Tambussi, Giuseppe, McClure, Myra, Schechter, Mauro, Jonathan Weber, Babiker Abdel, Plana Prades, Montserrat, Kholoud Porter, Abdel Babiker, Cooper, David A, Kholoud Porter (252703), Emery, Sean, Okulicz Jason F., Fiona M Ewings, Cooper, DA, INSIGHT SMART, David A Cooper (16165874), Court Pedersen, SPARTAC Trial Investigators, INSIGHT SMART and SPARTAC Investigators, Phillips, Rodney, Fidler Sarah, Myra McClure, Ligero, M. C., Pedersen, C, Elizabeth Hamlyn, Pumarola Suñé, Tomàs, Tuset Creus, Montserrat, Porter, K, Schechter Mauro, McClure, M, Mauro Schechter, Babiker, Abdel, Ewings, FM, The INSIGHT SMART and SPARTAC Investigators (16174844), Martin Fisher (300134), Fidler, S, Okulicz, Jason F., McClure Myra, Arnaiz Gargallo, Juan Alberto, Cooper, David A., Giuseppe Tambussi, Sarah Fidler, Weber Jonathan, Sarah Fidler (76851), Ewings, Fiona M., Okulicz, JF, Gatell, José M., Fidler, Sarah, Okulicz, Jason F, David A Cooper, SPARTAC Investigator, Tambussi Giuseppe, Mauro Schechter (4928), INSIGHT SMART Investigator, Fiona M Ewings (16174838), Ewings Fiona M., Porter Kholoud, Gallart, Teresa, Ewings, Fiona M +83 morecore +1 more sourceConstrained pattern of viral evolution in acute and early HCV infection limits viral plasticity [PDF]
, 2011 Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...Paul Klenerman, Malte Heeg, John, Mina, Pfafferott, K, James, Ian, Ulsenheimer, Axel, Helmut M. Diepolder, Lucas, A.D., Silvana Gaudieri, Heeg, M, Rauch, A, Ian James, John, M., Andri Rauch, Klenerman, P., James, I, Simon Mallal, Diepolder, HM, Heeg, Malte, John, M, Mallal, Simon, Lucas, Andrew, Nolan, D., Lucas, M., Heeg, M., Michaela Lucas, Diepolder, H.M., Mallal, S., Gaudieri, S, Lucas, M, Gaudieri, S., Nolan, David, Ulsenheimer, A, Lucas, A, David Nolan, Klenerman, Paul, Diepolder, Helmut M., Pfafferott, K., Klenerman, P, Rauch, A., Ulsenheimer, A., Pfafferott, Katja, Lucas, Michaela, Katja Pfafferott, Andrew Lucas, Rauch, Andri, Diepolder, Helmut M, Axel Ulsenheimer, Mina John, Helmut M Diepolder, Nolan, D, Mallal, S, James, I., Gaudieri, Silvana +53 morecore +3 more sourcesHCV treatment for prevention among people who inject drugs: Modeling treatment scale-up in the age of direct-acting antivirals. [PDF]
, 2013 UNLABELLED: Substantial reductions in hepatitis C virus (HCV) prevalence among people who inject drugs (PWID) cannot be achieved by harm reduction interventions such as needle exchange and opiate substitution therapy (OST) alone. Current HCV treatment is Dillon, John, Hellard, M, Grebely, J ; https://orcid.org/, Hellard, Margaret, Goldberg, David J., Martin, Natasha K, Goldberg, DJ, Vickerman, P, Dore, Gregory J, Goldberg, David, Hickman, M ; https://orcid.org/, Hickman, Matthew, Lima, Viviane D, Grebely, J, Hutchinson, SJ, Dillon, John F.; id_orcid, Foster, Graham R., Lima, Viviane, Hickman, M, Martin, Natasha, Hutchinson, Sharon J.; id_orcid, Lima, VD, Martin, NK, Dore, Gregory J., Foster, Graham, Lima, Viviane D., Dore, Gregory, Vickerman, Peter, Goldberg, David J, Dillon, John F, Grebely, Jason, Hutchinson, Sharon, Hutchinson, Sharon J., Foster, Graham R, Dillon, JF, Dore, GJ ; https://orcid.org/, Foster, GR, Dillon, John F., Dore, GJ, Hutchinson, Sharon J, Martin, Natasha K. +40 morecore +1 more sourceMammalian-adaptive mutation NP-Q357K in Eurasian H1N1 Swine Influenza viruses determines the virulence phenotype in mice
Emerging Microbes and Infections, 2019 It has recently been proposed that the Eurasian avian-like H1N1 (EA H1N1) swine influenza virus (SIV) is one of the most likely zoonotic viruses to cause the next influenza pandemic.Wenfei Zhu, Zhaomin Feng, Yongkun Chen, Lei Yang, Jia Liu, Xiyan Li, Suli Liu, Lijuan Zhou, Hejiang Wei, Rongbao Gao, Dayan Wang, Yuelong Shu +11 moredoaj +1 more sourceTreatment interruption and variation in tablet taking behaviour result in viral failure: a case-control study from Cape Town, South Africa. [PDF]
, 2011 BACKGROUND: Understanding of the impact of non-structured treatment interruption (TI) and variation in tablet-taking on failure of first-line antiretroviral therapy (ART) is limited in a resource-poor setting.Orrell, Catherine, Lisa-Noelle Ncaca, Katharina Kranzer, Ncaca Lisa-Noelle, Orrell Catherine, Kranzer, Katharina, Ncaca, Lisa-Noelle, Catherine Orrell, Kranzer Katharina +8 morecore +1 more sourceApplication of α-Syn Real-Time Quaking-Induced Conversion for Brain and Skin Specimens of the Chinese Patients With Parkinson’s Disease
Frontiers in Aging Neuroscience, 2022 The real-time quaking-induced conversion (RT-QuIC) assay has been developed and used as an in vitro diagnostic tool for Parkinson’s disease (PD). In this study, we established α-Syn RT-QuIC using recombinant human α-Syn as the substrate.Dong-Dong Chen, Ling Jiao, Yue Huang, Kang Xiao, Li-Ping Gao, Cao Chen, Cao Chen, Qi Shi, Qi Shi, Xiao-Ping Dong, Xiao-Ping Dong, Xiao-Ping Dong, Xiao-Ping Dong +12 moredoaj +1 more source
