Results 21 to 30 of about 8,443,463 (315)

Substitution of D701N in the PB2 protein could enhance the viral replication and pathogenicity of Eurasian avian-like H1N1 swine influenza viruses

open access: yesEmerging Microbes and Infections, 2018
Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses (SIVs) have become predominant in pig populations in China and have recently been reported to have the most potential to raise the next pandemic in humans.
Suli Liu   +8 more
doaj   +1 more source

The Dynamic Change in Plasma Epstein–Barr Virus DNA Load over a Long-Term Follow-Up Period Predicts Prognosis in Nasopharyngeal Carcinoma

open access: yesViruses, 2022
The current study was designed to investigate the changes in the circulating Epstein–Barr virus DNA load (EBV DNA) at various time points before and after treatment and its clinical significance in nasopharyngeal carcinoma (NPC).
Amina Gihbid   +13 more
doaj   +1 more source

Diagnosis and treatment of viral encephalitis [PDF]

open access: yesPostgraduate Medical Journal, 2002
Abstract Acute encephalitis constitutes a medical emergency. In most cases, the presence of focal neurological signs and focal seizures will distinguish encephalitis from encephalopathy. Acute disseminated encephalomyelitis is a non-infective inflammatory encephalitis that may require to be treated with steroids.
A, Chaudhuri, P G E, Kennedy
openaire   +2 more sources

Viral Pneumonia: Etiologies and Treatment [PDF]

open access: yesJournal of Investigative Medicine, 2018
Viral pathogens are increasingly recognized as a cause of pneumonia, in immunocompetent patients and more commonly among immunocompromised. Viral pneumonia in adults could present as community-acquired pneumonia (CAP), ranging from mild disease to severe disease requiring hospital admission and mechanical ventilation.
Dima, Dandachi   +1 more
openaire   +2 more sources

Molecular characterization of H6 subtype influenza viruses in southern China from 2009 to 2011

open access: yesEmerging Microbes and Infections, 2016
H6 avian influenza viruses (AIVs), which are prevalent in domestic and wild birds in Eurasian countries, have been isolated from pigs, a dog and a human.
Shumei Zou   +8 more
doaj   +1 more source

A Gene Constellation in Avian Influenza A (H7N9) Viruses May Have Facilitated the Fifth Wave Outbreak in China

open access: yesCell Reports, 2018
Summary: The 2016–2017 epidemic of influenza A (H7N9) virus in China prompted concern that a genetic change may underlie increased virulence. Based on an evolutionary analysis of H7N9 viruses from all five outbreak waves, we find that additional ...
Wenfei Zhu   +21 more
doaj   +1 more source

ENT1 and treatment of viral diseases

open access: yesOncotarget, 2015
Ribavirin (RBV) is a synthetic nucleoside analogue (1-b-D-ribofuranosyl-1, 2,4-triazole-3-carboxamide) used for the treatment of a number of viral diseases. RBV inhibits inosine 5′-phosphate dehydrogenase (IMPDH), the enzyme required for synthesis of guanosine monophosphate (GMS) as well as DNA and RNA synthesis.
Rajesh, Panigrahi, Srikanta, Dash
openaire   +2 more sources

Significant enhanced expressions of aquaporin-1, -4 and -9 in the brains of various prion diseases

open access: yesPrion, 2019
Aquaporins (AQPs) are widely expressed in various types of tissues, among them AQP1, AQP4 and AQP9 are expressed predominately with relatively special distributing features in various brain regions.
Qi Shi   +9 more
doaj   +1 more source

Increased urbanization reduced the effectiveness of school closures on seasonal influenza epidemics in China

open access: yesInfectious Diseases of Poverty, 2021
Background School closure is a common mitigation strategy during severe influenza epidemics and pandemics. However, the effectiveness of this strategy remains controversial.
Hao Lei   +7 more
doaj   +1 more source

Activation of the interferon induction cascade by influenza A viruses requires viral RNA synthesis and nuclear export [PDF]

open access: yes, 2014
This work is supported by grants from the Wellcome Trust (grants 087751/A/08/Z) and MRC (G1001726/1).We have examined the requirements for virus transcription and replication and thus the roles of input and progeny genomes in the generation of interferon
Randall, Richard E   +3 more
core   +1 more source

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