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Viral vector-based influenza vaccines [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2016
Antigenic drift of seasonal influenza viruses and the occasional introduction of influenza viruses of novel subtypes into the human population complicate the timely production of effective vaccines that antigenically match the virus strains that cause ...
Rimmelzwaan, G.F. (Guus)   +1 more
core   +7 more sources

Viral Vector-Based Gene Therapy. [PDF]

open access: yesInt J Mol Sci, 2023
Gene therapy is a technique involving the modification of an individual’s genes for treating a particular disease. The key to effective gene therapy is an efficient carrier delivery system. Viral vectors that have been artificially modified to lose their
Li X   +5 more
europepmc   +2 more sources

Viral vector platforms within the gene therapy landscape

open access: yesSignal Transduction and Targeted Therapy, 2021
Throughout its 40-year history, the field of gene therapy has been marked by many transitions. It has seen great strides in combating human disease, has given hope to patients and families with limited treatment options, but has also been subject to many
J. Bulcha   +4 more
semanticscholar   +1 more source

HIV-1 subtype diversity, phylogenetic analysis and study of drug resistance in strains circulating in the Ural Federal District

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2022
Introduction. Ural Federal District (UFD) has been one of the most HIV-affected areas in the Russian Federation during past 20 years. The total number of people living with HIV/AIDS (PLWH) and receiving antiretroviral therapy (ART) exceeds 100,000 (61.7%
M. V. Piterskiy   +4 more
doaj   +1 more source

Viral Vector Vaccine Development and Application during the COVID-19 Pandemic

open access: yesMicroorganisms, 2022
With the accumulation of mutations in SARS-CoV-2 and the continuous emergence of new variants, the importance of developing safer and effective vaccines has become more prominent in combating the COVID-19 pandemic.
Shaofeng Deng   +11 more
semanticscholar   +1 more source

Characterisation of new animal cell cultures’ sensitivity to Coxsackievirus B5 and Herpes simplex virus‑1

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
The increase in the number of cell cultures for virology and biotechnology enhances the chances of a successful response to threats related to outbreaks of well-known and new human infectious diseases.
Yu. A. Zakharova   +4 more
doaj   +1 more source

Side Effects of mRNA-Based and Viral Vector-Based COVID-19 Vaccines among German Healthcare Workers

open access: yesBiology, 2021
Simple Summary The main way to overcome the COVID-19 pandemic is mass vaccination of the public. However, the public’s vaccine hesitancy toward the available vaccines is a big challenge in the fighting against the coronavirus spreading.
M. Klugar   +6 more
semanticscholar   +1 more source

Viral vector‐based gene therapies in the clinic

open access: yesBioengineering & Translational Medicine, 2021
Gene therapies are currently one of the most investigated therapeutic modalities in both the preclinical and clinical settings and have shown promise in treating a diverse spectrum of diseases.
Zongmin Zhao, A. Anselmo, S. Mitragotri
semanticscholar   +1 more source

Assessment of Seroprevalence to SARS-CoV-2 in Various Population Cohorts Using Logit Regression Models During Initial Period of Herd Immunity Formation

open access: yesПроблемы особо опасных инфекций, 2022
The aim of the study was to assess the dynamics of seroprevalence to SARS-CoV-2 in various population groups during the initial period of herd immunity formation based on multivariate analysis using logit regression models.Materials and methods.
V. A. Mishchenko   +10 more
doaj   +1 more source

Cancer Gene Therapy Goes Viral: Viral Vector Platforms Come of Age

open access: yesRadiology and Oncology, 2022
Background Since the advent of viral vector gene therapy in 1990s, cancer treatment with viral vectors promised to revolutionize the field of oncology.
Urban Bezeljak
semanticscholar   +1 more source

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