Results 1 to 10 of about 2,924,139 (391)
Viral Hybrid Vectors for Somatic Integration - Are They the Better Solution? [PDF]
, 2009 The turbulent history of clinical trials in viral gene therapy has taught us important lessons about vector design and safety issues. Much effort was spent on analyzing genotoxicity after somatic integration of therapeutic DNA into the host genome. Based
Ehrhardt, Anja +2 more
core +6 more sources
Viral Vector Preparation [PDF]
Definitions, 2020 National Cancer Institute
semanticscholar +3 more sources
Viral Vector-Based Gene Therapy. [PDF]
Int J Mol Sci, 2023 Gene therapy is a technique involving the modification of an individual’s genes for treating a particular disease. The key to effective gene therapy is an efficient carrier delivery system. Viral vectors that have been artificially modified to lose their
Li X +5 more
europepmc +2 more sources
Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases [PDF]
Frontiers in Molecular Neuroscience, 2020 Diseases of the central nervous system (CNS) have historically been among the most difficult to treat using conventional pharmacological approaches.
Joseph Edward Rittiner +10 more
doaj +2 more sources
Viral vector-based influenza vaccines [PDF]
Human Vaccines & Immunotherapeutics, 2016 Antigenic drift of seasonal influenza viruses and the occasional introduction of influenza viruses of novel subtypes into the human population complicate the timely production of effective vaccines that antigenically match the virus strains that cause ...
Rimmelzwaan, G.F. (Guus) +1 more
core +4 more sources
Viral vector platforms within the gene therapy landscape
Signal Transduction and Targeted Therapy, 2021 Throughout its 40-year history, the field of gene therapy has been marked by many transitions. It has seen great strides in combating human disease, has given hope to patients and families with limited treatment options, but has also been subject to many
J. Bulcha +4 more
semanticscholar +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2022 Introduction. Ural Federal District (UFD) has been one of the most HIV-affected areas in the Russian Federation during past 20 years. The total number of people living with HIV/AIDS (PLWH) and receiving antiretroviral therapy (ART) exceeds 100,000 (61.7%
M. V. Piterskiy +4 more
doaj +1 more source
Viral Vector Vaccine Development and Application during the COVID-19 Pandemic
Microorganisms, 2022 With the accumulation of mutations in SARS-CoV-2 and the continuous emergence of new variants, the importance of developing safer and effective vaccines has become more prominent in combating the COVID-19 pandemic.
Shaofeng Deng +11 more
semanticscholar +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2023 The increase in the number of cell cultures for virology and biotechnology enhances the chances of a successful response to threats related to outbreaks of well-known and new human infectious diseases.
Yu. A. Zakharova +4 more
doaj +1 more source
Side Effects of mRNA-Based and Viral Vector-Based COVID-19 Vaccines among German Healthcare Workers
Biology, 2021 Simple Summary The main way to overcome the COVID-19 pandemic is mass vaccination of the public. However, the public’s vaccine hesitancy toward the available vaccines is a big challenge in the fighting against the coronavirus spreading.
M. Klugar +6 more
semanticscholar +1 more source