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Viral vector-based influenza vaccines [PDF]
Antigenic drift of seasonal influenza viruses and the occasional introduction of influenza viruses of novel subtypes into the human population complicate the timely production of effective vaccines that antigenically match the virus strains that cause ...
Rimmelzwaan, G.F. (Guus)+1 more
core +7 more sources
Viral Vector-Based Gene Therapy. [PDF]
Gene therapy is a technique involving the modification of an individual’s genes for treating a particular disease. The key to effective gene therapy is an efficient carrier delivery system. Viral vectors that have been artificially modified to lose their
Li X+5 more
europepmc +2 more sources
Viral vector platforms within the gene therapy landscape
Throughout its 40-year history, the field of gene therapy has been marked by many transitions. It has seen great strides in combating human disease, has given hope to patients and families with limited treatment options, but has also been subject to many
J. Bulcha+4 more
semanticscholar +1 more source
Introduction. Ural Federal District (UFD) has been one of the most HIV-affected areas in the Russian Federation during past 20 years. The total number of people living with HIV/AIDS (PLWH) and receiving antiretroviral therapy (ART) exceeds 100,000 (61.7%
M. V. Piterskiy+4 more
doaj +1 more source
Viral Vector Vaccine Development and Application during the COVID-19 Pandemic
With the accumulation of mutations in SARS-CoV-2 and the continuous emergence of new variants, the importance of developing safer and effective vaccines has become more prominent in combating the COVID-19 pandemic.
Shaofeng Deng+11 more
semanticscholar +1 more source
The increase in the number of cell cultures for virology and biotechnology enhances the chances of a successful response to threats related to outbreaks of well-known and new human infectious diseases.
Yu. A. Zakharova+4 more
doaj +1 more source
Side Effects of mRNA-Based and Viral Vector-Based COVID-19 Vaccines among German Healthcare Workers
Simple Summary The main way to overcome the COVID-19 pandemic is mass vaccination of the public. However, the public’s vaccine hesitancy toward the available vaccines is a big challenge in the fighting against the coronavirus spreading.
M. Klugar+6 more
semanticscholar +1 more source
Viral vector‐based gene therapies in the clinic
Gene therapies are currently one of the most investigated therapeutic modalities in both the preclinical and clinical settings and have shown promise in treating a diverse spectrum of diseases.
Zongmin Zhao, A. Anselmo, S. Mitragotri
semanticscholar +1 more source
The aim of the study was to assess the dynamics of seroprevalence to SARS-CoV-2 in various population groups during the initial period of herd immunity formation based on multivariate analysis using logit regression models.Materials and methods.
V. A. Mishchenko+10 more
doaj +1 more source
Cancer Gene Therapy Goes Viral: Viral Vector Platforms Come of Age
Background Since the advent of viral vector gene therapy in 1990s, cancer treatment with viral vectors promised to revolutionize the field of oncology.
Urban Bezeljak
semanticscholar +1 more source