Results 161 to 170 of about 156,575 (279)

In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism. [PDF]

Nat Commun
Fokine A, Zhu J, Klose T, Vago F, Arnaud CA, Wang Z, Khare B, Rossmann MG, Chen Z, Sun L, Fang Q, Kuhn RJ, Rao VB.   +12 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Adipose Tissue in SARS‐CoV‐2 Viral Tropism, Viral Replication, and the Concept of a Viral Reservoir: An Update

Obesity, Volume 34, Issue 3, Page 519-523, March 2026.
Adipose tissue as a potential reservoir for and modifier of SARS‐CoV‐2 infection and its complications. Schematic demonstrating the differences in subcutaneous and visceral adipose tissue and infection capacity of SARS‐CoV‐2 with interplay between macrophages and adipocytes as target cells for viral tropism.
Liam Charles Maher, Paul M. Ryan, Noel M. Caplice   +2 more
wiley   +1 more source

A cluster of acidic residues in the cytoplasmic domain of SARS-CoV-2 Spike is required for virion-incorporation and infectivity. [PDF]

PLoS One
Stoneham CA, Singh R, De Leon A, Tafelmeyer P, Acosta F, Fuori A, Anderson M, Ramirez PW, Schwartzer-Sperber HS, Pillai S, Lewinski MK, Guatelli J.   +11 more
europepmc   +1 more source

A novel glycoform of the rotavirus outer capsid protein VP7 is secreted from polarized cells and activates innate immune cells. [PDF]

J Virol
Nutsford A, Chau TH, Wang C, Sargent A, Cullen C, Reilly T, Thaysen-Andersen M, Brooks AES, Taylor JA.   +8 more
europepmc   +1 more source

Structural Basis of MERS‐CoV Receptor Interactions and Antibody Neutralisations

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Increasing outbreaks of coronaviruses underscore the importance of antivirals and vaccines that can combat a wide range of coronaviruses. Neutralising antibodies (nAbs), along with vaccines and small‐molecule drugs, are among the most promising treatments and prevention options against coronaviruses.
Edem Gavor, Yeu Khai Choong, Sunil Singh, Hariharan Sivaraman, Er Shi Yin, J. Sivaraman   +5 more
wiley   +1 more source

SARS-CoV-2 nucleocapsid protein forms complexes with soluble complement regulatory proteins that can bind to the virion. [PDF]

Sci Rep
Víglaský J, Bhide K, Talpasova L, Fialová Ľ, Bhide M.   +4 more
europepmc   +1 more source

Langat Virus Biology and Infection

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova, Daniel Sauter, Michael Schindler, Thomas Iftner   +3 more
wiley   +1 more source

Ensemble Docking of FDA‐Approved and Peruvian Phytochemicals Against Monkeypox Virus Telomere‐Binding Protein

ChemistrySelect, Volume 11, Issue 9, 5 March 2026.
ABSTRACT Monkeypox is a reemerging zoonotic disease that has been spreading worldwide. Different approaches are being conducted to find effective treatments for this disease. To accelerate therapeutic discovery, we propose telomere‐binding protein (TBP) as a potential drug target because of its important role during virus maturation.
Edinson Gervacio‐Villarreal, Georcki Ropón‐Palacios, Claudina Sancho, Jhon Pérez‐Silva, Kewin Otazu, Gustavo E. Olivos‐Ramirez, Karolyn Vega‐Chozo, Yaritza L. Ramirez‐Díaz, Manuel E. Chenet‐Zuta, Ivonne Navarro del Aguila, Mario De la Cruz Flores, Cinthia Aguiar, Ihosvany Camps   +12 more
wiley   +1 more source

ICTV Virus Taxonomy Profile: <i>Apasviridae</i> 2026. [PDF]

J Gen Virol
Prabhu A, Rinke C.
europepmc   +1 more source