Results 31 to 40 of about 156,575 (279)
An Update of the Virion Proteome of Kaposi Sarcoma-Associated Herpesvirus
Viruses, 2020 The virion proteins of Kaposi sarcoma-associated herpesvirus (KSHV) were initially characterized in 2005 in two separate studies that combined the detection of 24 viral proteins and a few cellular components via LC-MS/MS or MALDI-TOF.
Ramina Nabiee +4 more
doaj +1 more source
Human Cytomegalovirus Primary Infection and Reactivation: Insights From Virion-Carried Molecules
Frontiers in Microbiology, 2020 Human cytomegalovirus (HCMV), a ubiquitous beta-herpesvirus, is able to establish lifelong latency after initial infection. Periodical reactivation occurs after immunosuppression, remaining a major cause of death in immunocompromised patients.
Yu-Qing Wang +2 more
doaj +1 more source
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
, 2016 Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino +5 more
core +1 more source
Identification of the 15FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion
Retrovirology, 2004 The auxiliary regulatory protein Vpr of HIV-1 is packaged in the virion through interaction with the Gag C-terminal p6 domain. Virion packaging of Vpr is critical for Vpr to exert functions in the HIV-1 life cycle.
Zhu Henghu, Jian Heng, Zhao Ling-Jun
doaj +1 more source
Intravirion DNA Can Access the Space Occupied by the Bacteriophage P22 Ejection Proteins
Viruses, 2021 Tailed double-stranded DNA bacteriophages inject some proteins with their dsDNA during infection. Phage P22 injects about 12, 12, and 30 molecules of the proteins encoded by genes 7, 16 and 20, respectively.
Justin C. Leavitt +4 more
doaj +1 more source
Zika Virus NS2A-Mediated Virion Assembly
mBio, 2019 The flavivirus virion consists of an envelope outer layer, formed by envelope (E) and membrane (M) proteins on a lipid bilayer, and an internal core, formed by capsid (C) protein and genomic RNA. The molecular mechanism of flavivirus assembly is not well
Xianwen Zhang +7 more
doaj +1 more source
Quantitative Imaging of Single, Unstained Viruses with Coherent X-rays
, 2008 Since Perutz, Kendrew and colleagues unveiled the structure of hemoglobin and myoglobin based on X-ray diffraction analysis in the 1950s, X-ray crystallography has become the primary methodology used to determine the 3D structure of macromolecules ...
A. C. Steven +11 more
core +1 more source
Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]
, 2016 American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S. +4 more
core +2 more sources
Morphogenesis of the infectious HIV-1 virion
Frontiers in Microbiology, 2011 The virion of HIV-1 is spherical and viral glycoprotein spikes (gp120, gp41) protrude from its envelope. The characteristic cone-shaped core exists within the virion, caging the ribonucleoprotein (RNP) complex, which is comprised of viral RNA ...
Jun-Ichi eSakuragi
doaj +1 more source
Current estimates for HIV-1 production imply rapid viral clearance in lymphoid tissues. [PDF]
PLoS Computational Biology, 2010 It has recently been estimated that a single HIV-1 infected cell produces between and more than viral particles over its life span. Since body-wide estimates of the ratio of free virus to productively infected cells are smaller than and much smaller than
Rob J De Boer +2 more
doaj +1 more source