Results 51 to 60 of about 3,105,782 (329)

Management of Virologic Failure and HIV Drug Resistance

Infectious Disease Clinics of North America, 2019
Approximately 20% of people with HIV in the United States prescribed antiretroviral therapy are not virally suppressed. Thus, optimal management of virologic failure has a critical role in the ability to improve viral suppression rates to improve long-term health outcomes for those infected and to achieve epidemic control.
Suzanne M, McCluskey, Mark J, Siedner, Vincent C, Marconi   +2 more
openaire   +3 more sources

Magnitude and Determinants of Virological Failure Among Patients >15 Years on Anti-Retroviral Therapy in Rural Lesotho Between 2015 and 2019 – A Retrospective Cohort Study

HIV/AIDS: Research and Palliative Care, 2023
Thabo Ishmael Lejone,1,2 Ozayr Mahomed1 1SolidarMed, Lesotho, South Africa; 2Discipline of Public Health Medicine, University of KwaZulu Natal, Durban, South AfricaCorrespondence: Ozayr Mahomed, Howard College, University of KwaZulu Natal, 227 George ...
Lejone TI, Mahomed O
doaj  

Predictors of Virological Failure and Time to Viral Suppression of First-Line Integrase Inhibitor–Based Antiretroviral Treatment

Clinical Infectious Diseases, 2020
Background Integrase strand transfer inhibitors (InSTIs) are recommended for first-line treatment of persons with human immunodeficiency virus (HIV). We identified risk factors, including baseline minor InSTI resistance mutations, for treatment failure ...
Ashima Pyngottu, A. Scherrer, R. Kouyos, M. Huber, H. Hirsch, M. Perreau, S. Yerly, A. Calmy, M. Cavassini, M. Stöckle, H. Furrer, P. Vernazza, E. Bernasconi, H. Günthard, K A M E J D L H C A M A G M L J J H C A H F D B H H Aebi-Popp Anagnostopoulos Battegay Bernasconi Böni, K. Aebi-Popp, A. Anagnostopoulos, M. Battegay, E. Bernasconi, J. Böni, D. Braun, H. Bucher, A. Calmy, M. Cavassini, A. Ciuffi, G. Dollenmaier, M. Egger, L. Elzi, J. Fehr, J. Fellay, H. Furrer, C. Fux, H. Günthard, D. Haerry, B. Hasse, H. Hirsch, M. Hoffmann, I. Hösli, M. Huber, C. Kahlert, L. Kaiser, O. Keiser, T. Klimkait, R. Kouyos, H. Kovari, B. Ledergerber, G. Martinetti, B. Martinez de Tejada, C. Marzolini, K. Metzner, N. Müller, D. Nicca, P. Paioni, G. Pantaleo, M. Perreau, A. Rauch, C. Rudin, A. Scherrer, P. Schmid, R. Speck, M. Stöckle, P. Tarr, A. Trkola, P. Vernazza, G. Wandeler, R. Weber, S. Yerly   +66 more
semanticscholar   +1 more source

Virological efficacy of PI monotherapy for HIV-1 in clinical practice. [PDF]

, 2016
BACKGROUND: Clinical trials of PI monotherapy indicate that most participants maintain viral suppression and emergent protease resistance is rare.
Collier, D, Copas, AJ, El Bouzidi, K, Gupta, RK, Miller, RF, Nastouli, E   +5 more
core   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Determinants of Virological Failure Among Patients on First-line Antiretroviral Therapy in Central Oromia, Ethiopia: A Case–Control Study

HIV/AIDS, 2020
Background Viral suppression among people living with HIV is the main goal of antiretroviral therapy (ART). Despite the treatment, more than four million people and over 55 thousand patients globally and in Ethiopia had virological failure respectively ...
Ilili Jemal Abdullahi, H. A. Deybasso, Abebe Megerso Adlo   +2 more
semanticscholar   +1 more source

Adherence to Antiretroviral Therapy and Virologic Failure

Medicine, 2016
The often cited need to achieve ≥95% (nearly perfect) adherence to antiretroviral therapy (ART) for successful virologic outcomes in HIV may present a barrier to initiation of therapy in the early stages of HIV. This meta-analysis synthesized 43 studies (27,905 participants) performed across >26 countries, to determine the relationship between cut-off ...
Bezabhe, Woldesellassie M., Chalmers, Leanne, Bereznicki, Luke R., Peterson, Gregory M.   +3 more
openaire   +2 more sources

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Virological failure and HIV drug resistance among adults living with HIV on second‐line antiretroviral therapy in the Asia‐Pacific

HIV Medicine, 2020
To assess second‐line antiretroviral therapy (ART) virological failure and HIV drug resistance‐associated mutations (RAMs), in support of third‐line regimen planning in Asia.
J. Ross, A. Jiamsakul, N. Kumarasamy, I. Azwa, T. Merati, C. D. Do, M. Lee, P. S. Ly, E. Yunihastuti, K. Nguyen, R. Ditangco, O. T. Ng, J. Y. Choi, Shinichi Oka, Annette H. Sohn, Matthew Law   +15 more
semanticscholar   +1 more source

Leveraging corona virus disease 2019 vaccination to promote hepatitis C screening

Hepatology Communications, EarlyView., 2022
Abstract Health care initiatives, such as hepatitis C virus (HCV) screening, have been greatly overshadowed by the corona virus disease 2019 (COVID‐19) pandemic. However, COVID‐19 vaccination programs also provide an opportunity to engage with a high volume of people in a health care setting.
Aaron Vanderhoff, David Smookler, Mia J. Biondi, Scott Enman, Tintin Fuliang, Sana Mahmood, Agustina Crespi, Maria Marquez, Rafique Van Uum, Lucy You, Brett Wolfson‐Stofko, Renee Logan, Erin LeDrew, Hemant Shah, Harry Janssen, Camelia Capraru, Elisa Venier, Jordan J. Feld   +17 more
wiley   +1 more source