Results 151 to 160 of about 1,322 (161)

Recruitment of TRiC chaperonin in rotavirus viroplasms directly associates with virus replication

2022
AbstractRotavirus replication takes place in the viroplasms, cytosolic inclusions that allow the synthesis of virus genome segments and their encapsidation in the core shell followed by the addition of the second layer of the virion. The viroplasms are composed of several viral proteins, including NSP5, which is the main building block.
Janine Vetter, Guido Papa, Kurt Tobler, Manuel Kley, Michael Myers, Mahesa Wiesendanger, Elisabeth M. Schraner, Oscar R. Burrone, Cornel Fraefel, Catherine Eichwald   +9 more
openaire   +1 more source

Rotavirus Replication: Plus-Sense Templates for Double-Stranded RNA Synthesis Are Made in Viroplasms [PDF]

Journal of Virology, 2004
ABSTRACT Rotavirus plus-strand RNAs not only direct protein synthesis but also serve as templates for the synthesis of the segmented double-stranded RNA (dsRNA) genome. In this study, we identified short-interfering RNAs (siRNAs) for viral genes 5, 8, and 9 that suppressed the expression of NSP1, a nonessential protein; NSP2, a component of ...
Lynn S, Silvestri, Zenobia F, Taraporewala, John T, Patton   +2 more
exaly   +3 more sources

Relative localization of viroplasmic and endoplasmic reticulum-resident rotavirus proteins in infected cells

Archives of Virology, 2000
Replication of rotaviruses, whose capsid is constituted by three concentric layers of proteins, occurs in large cytoplasmic inclusions, termed viroplasms. Subviral, double-layered particles bud from viroplasms to the adjacent endoplasmic reticulum (ER), where the outermost protein layer, formed by VP4 and VP7, is assembled.
R A, González, R, Espinosa, P, Romero, S, López, C F, Arias   +4 more
openaire   +2 more sources

An electron microscopic study of cauliflower mosaic virus-induced viroplasms: Unusual structures within the viroplasm matrix with possible functional significance in the viral replication cycle

Journal of Ultrastructure and Molecular Structure Research, 1988
Abstract A detailed ultrastructural study has been performed on viroplasms induced by two Cauliflower mosaic virus (CaMV) strains. Thin-sectioning and negative-staining electron microscopy techniques were both used. Examination of purified viroplasms by negative staining has revealed additional details in their ultrastructure.
D. Rodríguez, D. López-Abella, J.R. Díaz-Ruiz   +2 more
openaire   +1 more source

COPII Vesicle Transport Is Required for Rotavirus NSP4 Interaction with the Autophagy Protein LC3 II and Trafficking to Viroplasms

Journal of Virology, 2019
Sue E Crawford, Jeanette M Criglar, James R Broughman   +2 more
exaly  

New Model for the Genesis and Maturation of Viroplasms Induced by Fijiviruses in Insect Vector Cells

Journal of Virology, 2013
Dongsheng Jia, Qian Chen, Taiyun Wei
exaly  

The Open Reading Frame VI Product of Cauliflower mosaic virus Is a Nucleocytoplasmic Protein: Its N Terminus Mediates Its Nuclear Export and Formation of Electron-Dense Viroplasms

Plant Cell, 2005
Kappei Kobayashi
exaly  

Assembly of viroplasms by viral nonstructural protein Pns9 is essential for persistent infection of rice gall dwarf virus in its insect vector

Virus Research, 2015
Lianhui Xie, Taiyun Wei
exaly  

Recombinant Rotaviruses Rescued by Reverse Genetics Reveal the Role of NSP5 Hyperphosphorylation in the Assembly of Viral Factories

Journal of Virology, 2019
Guido Papa, Francesca Arnoldi, Elisabeth M Schraner   +2 more
exaly  

Strand-specific viral DNA synthesis in purified viroplasms isolated from turnip leaves infected with cauliflower mosaic virus

Virology, 1985
exaly