Results 191 to 200 of about 13,638 (219)
Targeting gene-virotherapy of cancer [PDF]
Cell Research, 2006 Our purpose is to completely elimination of xenograft tumor in animal tumor model in order to work out a protocal for the cure of patient. Gene therapy and viral therapy for cancer have got some therapeutic effects, but both have no great breakthrough.
Xin Yuan, Liu, Jin Fa, Gu
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Oncolytic virotherapy of gynecologic malignancies
Gynecologic Oncology, 2011Gynecologic cancer is still the third leading cause of cancer death among women in the US. Therapeutics employing novel mechanisms of action are therefore urgently needed. Oncolytic viruses (OVs) selectively infecting and replicating in cancer cells have recently attracted considerable interest as promising anti-cancer agents.
Andreas D, Hartkopf +3 more
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Oncolytic virotherapy for multiple myeloma
Expert Opinion on Biological Therapy, 2008Current therapies for multiple myeloma (MM) are not curative, thus novel targeted therapeutics are being developed. One such targeted therapy is oncolytic virotherapy, wherein viruses specifically infect and kill the malignant plasma cells, leaving normal cells intact.This review provides an overview of the mechanisms and results of the oncolytic ...
Amaalia E, Stief, J Andrea, McCart
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Mathematical Modeling of Oncolytic Virotherapy
2019Mathematical modeling in biology has a long history as it allows the analysis and simulation of complex dynamic biological systems at little cost. A mathematical model trained on experimental or clinical data can be used to generate and evaluate hypotheses, to ask "what if" questions, and to perform in silico experiments to guide future experimentation
Johannes P W, Heidbuechel +3 more
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Immunomodulation in Oncolytic Measles Virotherapy
2019With the recognition of oncolytic virotherapy as an immunotherapy, the distinct interactions between oncolytic agents and the immune system have come into focus. The role of the immune system in oncolytic virotherapy is somewhat ambiguous: While preexisting or arising immunity directed against viral antigens may preclude efficient viral replication and
Laura, Dietz, Christine E, Engeland
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Oncolytic virotherapy-mediated anti-tumor response: a single-cell perspective
Cancer Cell, 2021Egle Ramelyte +2 more
exaly
Iranian journal of cancer prevention, 2014
New cancer therapies with novel mechanisms and functions are needed to treatpatients with different cancers. Virotherapy is a good scenario for such treatment. The advantages of virotherapy include the potential lack of cross resistance with standard therapies and the ability to cause tumor destruction by numerous mechanisms.
openaire +1 more source
New cancer therapies with novel mechanisms and functions are needed to treatpatients with different cancers. Virotherapy is a good scenario for such treatment. The advantages of virotherapy include the potential lack of cross resistance with standard therapies and the ability to cause tumor destruction by numerous mechanisms.
openaire +1 more source