Results 71 to 80 of about 4,403,980 (152)

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

MedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru, Dongliang Yuan, Shide Jiang, Xiaoxuan Zhao, Xu Liu, Yusheng Li, Shuguang Liu, Yuxiang Wu   +7 more
wiley   +1 more source

Virtual Bioequivalence Assessment of Tofacitinib Once Daily Modified Release Dosage Form in Pediatric Subjects

The AAPS Journal
Abstract Tofacitinib is a potent, selective inhibitor of the Janus kinase (JAK) family of kinases with a high degree of selectivity within the human genome’s set of protein kinases. Currently approved formulations for tofacitinib citrate are immediate release (IR) tablets, modified release (MR) tablets and IR solution.
Kazuko Sagawa, Vivek Purohit, Vu Le, Hao-Jui Hsu, Martin E. Dowty, Susanna Tse, Cheng Chang   +6 more
openaire   +2 more sources

Bioequivalence Study of Imatinib Formulations that Contain 400 mg in Healthy Colombians

, 2017
5 páginasA study with the aim to compare the bioavailability of two 400 mg imatinib formulations, test product Zeite® from Laboratorio Synthesis S.A.S., Colombia, and reference product Glivec® from Novartis Pharma, and determine if bioequivalence can be ...
Vargas M., Villarraga E.
core   +1 more source

Comparative bioequivalence studies of tramadol hydrochloride sustained-release 200 mg tablets

, 2010
Suhas S Khandave1, Satish V Sawant1, Santosh S Joshi1, Yatish K Bansal2, Sonal S Kadam21Accutest Research Laboratories (I) Private Limited, Koparkhirne, Navi Mumbai, Maharashtra, India; 2Ipca Laboratories Limited, Kandivli Mumbai, Maharashtra ...
Khandave Suhas, Satish V Sawant, et al, null Yatish Kumar Bansal, Santosh S Joshi, Suhas S Khandave, null Satish Sawant, null Sonal Sushil Kadam, null Santosh Joshi   +8 more
core   +1 more source

Motion Planning for Human Crowds: from Individuals to Groups of Virtual Characters [PDF]

, 2012
Virtual worlds, to become more lively and appealing, are typically populated by large crowds of virtual characters. One of the fundamental tasks that these characters have to perform is, on one hand, to plan their paths between different locations in the
Karamouzas, I., Sub Games & Virtual Worlds begr. 1/9/13, Games and Virtual Worlds   +2 more
core   +1 more source

Bioequivalence Study of Two 50 mg Desvenlafaxine Extended Release Formulations A Randomized, Single-Dose, Open-Label, Two Periods, Crossover Study

, 2014
4 páginasThis is a pharmacokinetic study of two formulations containing Desvenlafaxine succinate 50 mg extended release. Its objective was to compare the bioavailability between the Test product (Desvenlafaxine ER produced by Tecnoquímicas S.A., Colombia
Villarraga, E., Vargas, M., Vargas, Jba
core   +1 more source

Testing for Multivariate Equivalence with Random Quadratic Forms [PDF]

Multivariate equivalence testing becomes necessary whenever the similarity rather than a difference between several treatment groups with multiple endpoints has to be shown.
Weißbach, Rafael
core  

Virtual Museums – A Plea

Digital technologies have opened up new possibilities for the cultural sector. Many museums are represented on the internet with various materials. Augmented reality and virtual reality offer immersion experiences even for existing museums.
Böhmer, Otmar, Museums Forum, Virtual, Becker, Isabelle   +2 more
core   +1 more source

Logistic planning and drug formularies : considerations for clinically effective drug substitution [PDF]

, 2012
PhDDrug substitution is mainly economically not medically-driven; it can benefit healthcare services but does not directly benefit individual patients. Many healthcare providers have been promoting drug substitution in an attempt to contain their costs.
Alameri, Mubarak Nasser Mubarak Zain
core   +1 more source

Virtual Bioequivalence Frameworks and Workflows

We are developing advanced virtual bioequivalence (VBE) assessment models and methods, with a focus on the fundamentals of decision workflows in that context.This presentation covers: VBE workflows Advanced long-acting injectable and oral absorption models Case studies overview Software ...
openaire   +1 more source