The effect of treatment on pathogen virulence. [PDF]
The optimal virulence of a pathogen is determined by a trade-off between maximizing the rate of transmission and maximizing the duration of infectivity.
Galvani, Alison P+3 more
core
The interplay between mobilome and resistome in Staphylococcus aureus
Antibiotic resistance genes (ARGs) in Staphylococcus aureus can disseminate vertically through successful clones, but also horizontally through the transfer of genes conveyed by mobile genetic elements (MGEs).
Rachel Contarin+5 more
doaj +1 more source
Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment [PDF]
Bacterial resistance to antibiotic treatment is a huge concern: introduction of any new antibiotic is shortly followed by the emergence of resistant bacterial isolates in the clinic.
Dyson, Rosemary J.+3 more
core +2 more sources
Cyclosporiasis, caused by the coccidian parasite Cyclospora cayetanensis, has emerged as an increasing global public health concern, with the incidence of laboratory-confirmed domestically acquired cases in the US exceeding 10,000 since 2018.
Hui Zhu+10 more
doaj +1 more source
Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys+38 more
core +1 more source
First Report of CC5-MRSA-IV-SCCfus “Maltese Clone” in Bat Guano
Methicillin-resistant Staphylococcus aureus (MRSA) is a widespread pathogen that could cause different illnesses in both human and animals. Presence of MRSA in animals raises concerns of their capacity to act as reservoirs, particularly in wild animals ...
Assia Mairi+7 more
doaj +1 more source
Adherence to and Invasion of Human Intestinal Cells by Arcobacter Species and Their Virulence Genotypes [PDF]
The genus Arcobacter is composed of 17 species which have been isolated from various sources. Of particular interest are A. butzleri, A. cryaerophilus, and A.
Alkeskas, A+4 more
core +1 more source
The Virulence Index: A Metric for Quantitative Analysis of Phage Virulence
AbstractBackgroundOne of the main challenges in developing phage therapy and manufacturing phage products is the reliable evaluation of their efficacy, performance and quality. Since phage virulence is intrinsically difficult to fully capture, researchers have turned to rapid but partially inadequate methods for its evaluation.Materials and MethodsThe ...
Storms, Zachary+3 more
openaire +4 more sources
Background Despite their spread in daily practice, few data is available on clinical factors associated with peripherally inserted central catheter (PICC)-related bloodstream infections (PR-BSI). We aimed to assess the PR-BSI incidence, microbiology, and
Koko Barrigah-Benissan+8 more
doaj +1 more source
Extended-spectrum β-lactamases, transferable quinolone resistance, and virulotyping in extra-intestinal E. coli in Uruguay [PDF]
Introduction: To characterize extended-spectrum β-lactamases (ESBLs) and plasmid-mediated quinolone resistance (PMQR) genes in Escherichia coli isolates obtained from extra-intestinal samples in three Uruguayan hospitals.
Aguerrebere, Paula+10 more
core +2 more sources