Results 161 to 170 of about 13,136,107 (398)
The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid
Advanced Science, EarlyView.Functional bacterial amyloids such as CsgA and FapC have been widely studied to understand the relationship between aggregation and function. The recently solved structure of FapC reveals a Greek‐key motif in which extensive hydrogen bonding and packing interactions formed by residues in conserved imperfect repeats stabilize a β‐solenoid core.
Samuel Peña‐Díaz +12 more
wiley +1 more source
Advanced Science, EarlyView.To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao +12 more
wiley +1 more source
Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection [PDF]
, 2022 Shisong Jing +12 more
openalex +1 more source
Advanced Science, EarlyView.The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo +13 more
wiley +1 more source
Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces
Angewandte Chemie, EarlyView.Synthetic cellulose‐based oligomers assemble into supramolecular nanomaterials with a molecularly controlled, dense presentation of carbohydrates on their surfaces, serving as biological cues. Abstract The self‐assembly of molecular building blocks into ordered supramolecular structures enables the creation of nanomaterials that can display ligands on ...
Nives Hribernik +7 more
wiley +2 more sources
Arabidopsis YELLOW STRIPE-LIKE7 (YSL7) and YSL8 Transporters Mediate Uptake of Pseudomonas Virulence Factor Syringolin A into Plant Cells [PDF]
, 2013 Silvia Schelbert Hofstetter +3 more
openalex +1 more source
Advanced Science, EarlyView.This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song +14 more
wiley +1 more source
Angewandte Chemie, EarlyView.A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra +9 more
wiley +2 more sources
Advanced Science, EarlyView.To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong +5 more
wiley +1 more source