NSs: the multifaceted bunyavirus virulence factor [PDF]
npj VirusesBunyaviricetes represents a diverse class of RNA viruses, including hundreds of species distributed worldwide that threaten human and animal health. This Perspective briefly overviews bunyaviruses infecting humans and other mammals, focusing on their key
Maëva Duboeuf +3 more
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Do Bacterial “Virulence Factors” Always Increase Virulence? A Meta-analysis of Pyoverdine Production inPseudomonas aeruginosa as a Test Case [PDF]
Frontiers in Microbiology, 2016 Bacterial traits that contribute to disease are termed ‘virulence factors’ and there is much interest in therapeutic approaches that disrupt such traits.
Elisa Granato +4 more
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Virulence factors of Haemophilus ducreyi [PDF]
Infection and Immunity, 1984 We investigated the susceptibility of virulent and avirulent strains of Haemophilus ducreyi to the bactericidal activity of normal human serum and to phagocytosis and killing by human polymorphonuclear leukocytes (PMNL). Strains were defined as virulent if intradermal inoculation into a rabbit produced a typical necrotic lesion.
Joseph Odumeru +2 more
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Advancing virulence factor prediction using protein language models [PDF]
BMC BiologyBackground Bacterial infections rank as the second leading cause of death globally, with virulence factors (VFs) being crucial to their pathogenicity.
Yitong Liu +9 more
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Targeting anti-virulence factor strategies of bacterial pathogens [PDF]
Biosafety and HealthAntibiotic-resistant bacterial pathogens pose substantial biosafety and health hazards, leading to millions of deaths each year. The evolution of bacterial virulence factors is mainly propelled by horizontal gene transfer (HGT).
Jiashu Li, Tianyuan Jia, Liang Yang
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Virulence factors in endometrial cancer [PDF]
Cancer, 1993 AbstractThe majority of endometrial cancers are relatively benign and curable; there is a subset of virulent tumors that demands recognition. Factors that must be evaluated include: tumor grade, ploidy, steroid receptors, myometrial invasion, lymph node status, extrauterine disease or positive peritoneal fluid, and certain special tumors.
S.B. Gusberg
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Does virulence assessment of Vibrio anguillarum using sea bass (Dicentrarchus labrax) larvae correspond with genotypic and phenotypic characterization? [PDF]
, 2013 Background: Vibriosis is one of the most ubiquitous fish diseases caused by bacteria belonging to the genus Vibrio such as Vibrio (Listonella) anguillarum. Despite a lot of research efforts, the virulence factors and mechanism of V. anguillarum are still
Bossier, Peter +10 more
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Listeriolysin S, a Novel Peptide Haemolysin Associated with a Subset of Lineage I Listeria monocytogenes [PDF]
, 2008 peer-reviewedStreptolysin S (SLS) is a bacteriocin-like haemolytic and cytotoxic virulence factor that plays a key role in the virulence of Group A Streptococcus (GAS), the causative agent of pharyngitis, impetigo, necrotizing fasciitis and streptococcal
Casey, Patrick G. +7 more
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Microbial Virulence Factors [PDF]
International Journal of Molecular Sciences, 2020 Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease [...]
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Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila.
PLoS ONE, 2023 Quorum sensing is a communication strategy that bacteria use to collectively alter gene expression in response to cell density. Pathogens use quorum sensing systems to control activities vital to infection, such as the production of virulence factors and
Katie A Acken, Bo Li
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