Clonal Origin, Virulence Factors, and Virulence [PDF]
Infection and Immunity, 2000 The recent report from Picard et al. regarding extraintestinal Escherichia coli infections provides new insights into the relationships between clonal origin, virulence factor repertoire, and virulence (1). That clonal origin was only secondarily associated with virulence in this study was suggested by the finding that although mouse lethality was more
J R, Johnson, M, Kuskowski
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The Vibrio cholerae RND efflux systems impact virulence factor production and adaptive responses via periplasmic sensor proteins. [PDF]
PLoS Pathogens, 2018 Resistance-nodulation-division (RND) efflux systems are ubiquitous transporters in Gram-negative bacteria that are essential for antibiotic resistance. The RND efflux systems also contribute to diverse phenotypes independent of antimicrobial resistance ...
X Renee Bina +5 more
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Does virulence assessment of Vibrio anguillarum using sea bass (Dicentrarchus labrax) larvae correspond with genotypic and phenotypic characterization? [PDF]
, 2013 Background: Vibriosis is one of the most ubiquitous fish diseases caused by bacteria belonging to the genus Vibrio such as Vibrio (Listonella) anguillarum. Despite a lot of research efforts, the virulence factors and mechanism of V. anguillarum are still
Bossier, Peter +10 more
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The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses
Journal of Experimental Medicine, 2020 The ability of T. gondii to promote a STAT3- and STAT6-dependent M2 phenotype in macrophages by injecting the virulence factor ROP16 in cis and trans subsequently limits the magnitude of the parasite-specific T cell response.
Longfei Chen +12 more
semanticscholar +1 more source
Listeriolysin S, a Novel Peptide Haemolysin Associated with a Subset of Lineage I Listeria monocytogenes [PDF]
, 2008 peer-reviewedStreptolysin S (SLS) is a bacteriocin-like haemolytic and cytotoxic virulence factor that plays a key role in the virulence of Group A Streptococcus (GAS), the causative agent of pharyngitis, impetigo, necrotizing fasciitis and streptococcal
Casey, Patrick G. +7 more
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Proceedings of the National Academy of Sciences of the United States of America, 2008 Leron Katsir +4 more
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VFDB 2022: a general classification scheme for bacterial virulence factors
Nucleic Acids Res., 2021 The virulence factor database (VFDB, http://www.mgc.ac.cn/VFs/) is dedicated to presenting a comprehensive knowledge base and a versatile analysis platform for bacterial virulence factors (VFs).
Bo Liu +4 more
semanticscholar +1 more source
The splicing factor SR2 is an important virulence factor of Toxoplasma gondii
Frontiers in Microbiology, 2023 Serine/arginine-rich (SR) proteins are key factors with important roles in constitutive and alternative splicing (AS) of pre-mRNAs. However, the role of SR splicing factors in the pathogenicity of T. gondii remains largely unexplored.
Xiao-Jing Wu +10 more
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Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation [PDF]
, 2020 The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and ...
A Ghafoor +84 more
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Microfluidics-based liquid chromatography/mass spectrometry multiple reaction monitoring approach for the relative quantification of Burkholderia cenocepacia secreted virulence factors [PDF]
, 2018 Rationale: Burkholderia cenocepacia is an opportunistic pathogen that is commonly isolated from patients with cystic fibrosis (CF). Quorum sensing has been suggested to play a role in the activity of type II and type VI secretion systems and the release ...
Daled, Simon +6 more
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