Results 41 to 50 of about 4,443,372 (306)

Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage

Journal of Fungi, 2021
The activity of fumagillin, a mycotoxin produced by Aspergillus fumigatus, has not been studied in depth. In this study, we used a commercial fumagillin on cultures of two cell types (A549 pneumocytes and RAW 264.7 macrophages).
Xabier Guruceaga, Uxue Perez-Cuesta, Aize Pellon, Saioa Cendon-Sanchez, Eduardo Pelegri-Martinez, Oskar Gonzalez, Fernando Luis Hernando, Emilio Mayayo, Juan Anguita, Rosa M. Alonso, Nancy P. Keller, Andoni Ramirez-Garcia, Aitor Rementeria   +12 more
doaj   +1 more source

Special Issue “Sporothrix and Sporotrichosis 2.0”

Journal of Fungi, 2022
Sporotrichosis is a chronic fungal disease of humans and other mammals that often affects the skin and subcutaneous tissues and, rarely, deep-seated organs (most frequently in immunocompetent hosts) [...]
Héctor M. Mora-Montes
doaj   +1 more source

The genome of a pathogenic rhodococcus : cooptive virulence underpinned by key gene acquisitions [PDF]

, 2010
We report the genome of the facultative intracellular parasite Rhodococcus equi, the only animal pathogen within the biotechnologically important actinobacterial genus Rhodococcus. The 5.0-Mb R.
Parkhill Julian, Cherevach, Inna, Iain Macarthur, Sanders Mandy, Leadon, Desmond, Prescott John F., Navas, Jesús, Michal Letek, González Patricia, Tom C. Freeman, Navas Méndez, Jesús, Valero-Rello, Ana, Ruth Fahey, Leadon Desmond, Bentley, Stephen D., Holdstock Jolyon, Ursula Fogarty, Scortti, Mariela M., Hapeshi, Alexia, José A. Vázquez-Boland, Inna Cherevach, Buckley, Tom, Rodríguez, Héctor M., Rodríguez Héctor, Ocampo Alain, Valero-Rello Ana, Fogarty Ursula, Valero Rello, Ana, Prescott, John F., Quail Michael A., Rodríguez, Héctor, Jolyon Holdstock, Alain Ocampo, Sanders, Mandy, Héctor Rodríguez, Fogarty, Ursula, Vázquez-Boland José A., Ana Valero-Rello, MacArthur Iain, Freeman Tom C., González, Patricia, Ocampo, Alain, Ana Valero-Rello, Fahey Ruth, Desmond Leadon, Cherevach Inna, Blanco, Mónica, Mariela M. Scortti, MacArthur, Iain, Vázquez Boland, José A., Bentley Stephen D., John F Prescott, Wim G. Meijer, Quail, Michael A., John F. Prescott, Stephen D. Bentley, Vázquez-Boland, José A., José A Vázquez-Boland, Holdstock, Jolyon, Stephen D Bentley, Letek Michal, Meijer, Wim G., Blanco Mónica, Meijer Wim G., Mónica Blanco, Ocampo Sosa, Alain Antonio, Tom C Freeman, Julian Parkhill, Jolyon Holdstock, Hapeshi Alexia, Tom Buckley, Wim G Meijer, Mandy Sanders, Michael A. Quail, Letek, Michal, Michael A Quail, Alexia Hapeshi, Scortti Mariela M., Parkhill, Julian, Navas Jesús, Patricia González, Mariela M Scortti, González, Patricia Jiménez, Buckley Tom, Freeman, Tom C., Fahey, Ruth, Jesús Navas   +86 more
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Novel Models of Streptococcus canis Colonization and Disease Reveal Modest Contributions of M-Like (SCM) Protein

Microorganisms, 2021
Streptococcus canis is a common colonizing bacterium of the urogenital tract of cats and dogs that can also cause invasive disease in these animal populations and in humans. Although the virulence mechanisms of S.
Ingrid Cornax, Jacob Zulk, Joshua Olson, Marcus Fulde, Victor Nizet, Kathryn A Patras   +5 more
doaj   +1 more source

Pathogenic Determinants of the Mycobacterium kansasii Complex: An Unsuspected Role for Distributive Conjugal Transfer

Microorganisms, 2021
The Mycobacterium kansasii species comprises six subtypes that were recently classified into six closely related species; Mycobacterium kansasii (formerly M. kansasii subtype 1), Mycobacterium persicum (subtype 2), Mycobacterium pseudokansasii (subtype 3)
Florian Tagini, Trestan Pillonel, Claire Bertelli, Katia Jaton, Gilbert Greub   +4 more
doaj   +1 more source

Genetic diversity of Streptococcus suis isolates as determined by comparative genome hybridization [PDF]

, 2011
Background Streptococcus suis is a zoonotic pathogen that causes infections in young piglets. S. suis is a heterogeneous species. Thirty-three different capsular serotypes have been described, that differ in virulence between as well as within serotypes.
Smith, H.E., Schultsz, C, Baums Christoph G, de Bree, F.M., de Greeff Astrid, Ngo Thi, Hoa, Thi, Hoa Ngo, Christoph G Baums, Thi, HN, Hoa, N.T., Thi Hoa, Bree, F.M., de, Constance Schultsz, Stockhofe-Zurwieden, Norbert, Greeff, A., de, Wisselink Henk J, de Bree, Freddy M., Henk J Wisselink, Hoa Thi, Schultsz, Constance, Smith Hilde E, Hilde E Smith, Baums, Christoph G., Wisselink, H.J., de Bree, FM, Freddy M de Bree, Stockhofe-Zurwieden, N, Stockhofe-Zurwieden, N., Schultsz Constance, Schultsz, C., de Greeff, A, Smith, HE, Baums, CG, de Greeff, Astrid, de Bree Freddy M, de Greeff, A., Baums, C.G., Smith, Hilde E., Stockhofe-Zurwieden Norbert, Wisselink, HJ, Norbert Stockhofe-Zurwieden, Wisselink, Henk J., Astrid de Greeff   +42 more
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Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum [PDF]

, 2006
In many plant and animal bacterial pathogens, the Type III secretion system (TTSS) that directly translocates effector proteins into the eukaryotic host cells is essential for the development of disease.
Christian Boucher, Valls Marc, Valls i Matheu, Marc, Marc Valls, Boucher, Christian, Genin Stéphane, Genin, S., Boucher Christian, Stéphane Genin   +8 more
core   +2 more sources

Virulence factors of the family Legionellaceae

Microbiological Reviews, 1992
Whereas bacteria in the genus Legionella have emerged as relatively frequent causes of pneumonia, the mechanisms underlying their pathogenicity are obscure. The legionellae are facultative intracellular pathogens which multiply within the phagosome of mononuclear phagocytes and are not killed efficiently by polymorphonuclear leukocytes.
J N, Dowling, A K, Saha, R H, Glew
openaire   +2 more sources

Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo. [PDF]

, 2011
Mycobacterium tuberculosis dosRS two-component regulatory system controls transcription of approximately 50 genes including hspX, acg and Rv2030c, in response to hypoxia and nitric oxide conditions and within macrophages and mice.
Hu, Y, Yanmin Hu, Hu Yanmin, Anthony R M Coates, Anthony R. M. Coates, Coates, AR, Coates Anthony R. M.   +6 more
core   +2 more sources

The Epistemology of Bacterial Virulence Factor Characterization

Microorganisms
The field of microbial pathogenesis seeks to identify the agents and mechanisms responsible for disease causation. Since Robert Koch introduced postulates that were used to guide the characterization of microbial pathogens, technological advances have ...
Matthew Jackson, Susan Vineberg, Kevin R. Theis   +2 more
doaj   +1 more source