Results 21 to 30 of about 206,032 (260)

Vibrio cholerae ToxR Downregulates Virulence Factor Production in Response to Cyclo(Phe-Pro)

open access: yesmBio, 2013
Vibrio cholerae is an aquatic organism that causes the severe acute diarrheal disease cholera. The ability of V. cholerae to cause disease is dependent upon the production of two critical virulence determinants, cholera toxin (CT) and the toxin ...
X. Renee Bina   +4 more
doaj   +1 more source

Breaking the bad: Bacillus blocks fungal virulence factors

open access: yesMicrobial Cell, 2017
Fungal pathogens rely on the production of specific virulence factors during infection. Inhibiting such factors generally results in reduced fungal pathogenicity.
François L. Mayer, James W. Kronstad
doaj   +1 more source

Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors

open access: yesiScience, 2020
Summary: Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to ...
Diego López León   +7 more
doaj   +1 more source

Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata

open access: yesFrontiers in Cell and Developmental Biology, 2022
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that ...
Michiyo Okamoto   +15 more
doaj   +1 more source

The Avirulence Domain of Cauliflower mosaic virus Transactivator/Viroplasmin Is a Determinant of Viral Virulence in Susceptible Hosts

open access: yesMolecular Plant-Microbe Interactions, 2004
Cauliflower mosaic virus (CaMV) transactivator/viroplasmin (Tav) is a multifunctional protein essential for basic replication of CaMV. It also plays a role in viral pathogenesis in crucifer and solanaceous host plants.
Kappei Kobayashi, Thomas Hohn
doaj   +1 more source

Mobilization, Cloning, and Sequence Determination of a Plasmid-Encoded Polygalacturonase from a Phytopathogenic Burkholderia (Pseudomonas) cepacia

open access: yesMolecular Plant-Microbe Interactions, 1997
Phytopathogenic strains of Burkholderia cepacia (synonym Pseudomonas cepacia) produce endopolygalacturonase, whereas strains of clinical and soil origin do not.
Carlos F. Gonzalez   +3 more
doaj   +1 more source

Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage

open access: yesJournal of Fungi, 2021
The activity of fumagillin, a mycotoxin produced by Aspergillus fumigatus, has not been studied in depth. In this study, we used a commercial fumagillin on cultures of two cell types (A549 pneumocytes and RAW 264.7 macrophages).
Xabier Guruceaga   +12 more
doaj   +1 more source

Special Issue “Sporothrix and Sporotrichosis 2.0”

open access: yesJournal of Fungi, 2022
Sporotrichosis is a chronic fungal disease of humans and other mammals that often affects the skin and subcutaneous tissues and, rarely, deep-seated organs (most frequently in immunocompetent hosts) [...]
Héctor M. Mora-Montes
doaj   +1 more source

Novel Models of Streptococcus canis Colonization and Disease Reveal Modest Contributions of M-Like (SCM) Protein

open access: yesMicroorganisms, 2021
Streptococcus canis is a common colonizing bacterium of the urogenital tract of cats and dogs that can also cause invasive disease in these animal populations and in humans. Although the virulence mechanisms of S.
Ingrid Cornax   +5 more
doaj   +1 more source

Pathogenic Determinants of the Mycobacterium kansasii Complex: An Unsuspected Role for Distributive Conjugal Transfer

open access: yesMicroorganisms, 2021
The Mycobacterium kansasii species comprises six subtypes that were recently classified into six closely related species; Mycobacterium kansasii (formerly M. kansasii subtype 1), Mycobacterium persicum (subtype 2), Mycobacterium pseudokansasii (subtype 3)
Florian Tagini   +4 more
doaj   +1 more source

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