Results 31 to 40 of about 4,443,372 (306)

Steps toward broad-spectrum therapeutics : discovering virulence-associated genes present in diverse human pathogens [PDF]

, 2009
© 2009 Stubben et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Karlyshev, Andrey V., Gans, Jason D, Oyston, Petra C. F., Ford, Donna C., Gans, Jason D., Wolinsky Murray, Titball, Richard W., Cooper, Ian A, Karlyshev, Andrey, Wren, Brendan W, Cooper Ian A, Duffield Melanie L, Duffield, Melanie, Ford Donna C, Lingard, Bryan, Ford, Donna C, Stubben, Chris J., Wren, Brendan W., Oyston, Petra CF, Karlyshev, Andrey V, Titball, Rick W, Lingard, Brian, Duffield, Melanie L, Karlyshev Andrey V, Gans Jason D, Oyston Petra CF, Song, Jian, Stubben, Chris J, Oyston, Petra C F, Titball Rick W, de Rochefort Anna, Stubben Chris J, Wren Brendan W, Lingard Bryan, Wolinsky, Murray, de Rochefort, Anna, Cooper, Ian A., Song Jian   +37 more
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Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]

, 2010
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Peeters, B.P.H., Strategic Infection Biology, Dep Infectieziekten Immunologie, G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +9 more
core   +2 more sources

Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors

iScience, 2020
Summary: Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to ...
Diego López León, Patricia Matthey, Isabelle Fellay, Marianne Blanchard, Denis Martinvalet, Pierre-Yves Mantel, Luis Filgueira, Michael Walch   +7 more
doaj   +1 more source

Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata

Frontiers in Cell and Developmental Biology, 2022
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that ...
Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Kengo Tejima, Kaname Sasamoto, Masashi Yamaguchi, Toshihiro Aoyama, Minoru Nagi, Kohichi Tanabe, Yoshitsugu Miyazaki, Hironobu Nakayama, Chihiro Sasakawa, Chihiro Sasakawa, Susumu Kajiwara, Alistair J. P. Brown, Miguel C. Teixeira, Hiroji Chibana   +15 more
doaj   +1 more source

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus [PDF]

, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H., G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +7 more
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The Avirulence Domain of Cauliflower mosaic virus Transactivator/Viroplasmin Is a Determinant of Viral Virulence in Susceptible Hosts

Molecular Plant-Microbe Interactions, 2004
Cauliflower mosaic virus (CaMV) transactivator/viroplasmin (Tav) is a multifunctional protein essential for basic replication of CaMV. It also plays a role in viral pathogenesis in crucifer and solanaceous host plants.
Kappei Kobayashi, Thomas Hohn
doaj   +1 more source

Bacterial hemolysins as virulence factors [PDF]

Antonie van Leeuwenhoek, 1988
No abstract ...
Goebel, Werner, Chakraborty, T., Kreft, Jürgen   +2 more
openaire   +3 more sources

TroA of Streptococcus suis is required for manganese acquisition and full virulence [PDF]

, 2011
Streptococcus suis causes infections in pigs and occasionally in humans resulting in 23 manifestations as meningitis, sepsis, arthritis and septic shock. For survival within the 24 host, S. suis requires numerous nutrients including trace metals.
Smith, H.E., Rebel, M.J., Wichers Schreur, P.J., Rebel, J.M.J., van Putten, J.P.M., Jos P. M. van Putten, Johanna M. J. Rebel, Mari A. Smits, Paul J. Wichgers Schreur, Smits, M.A., Hilde E. Smith, Wichgers Schreur, P.J., Putten, J.P.M., van   +12 more
core   +1 more source

Mobilization, Cloning, and Sequence Determination of a Plasmid-Encoded Polygalacturonase from a Phytopathogenic Burkholderia (Pseudomonas) cepacia

Molecular Plant-Microbe Interactions, 1997
Phytopathogenic strains of Burkholderia cepacia (synonym Pseudomonas cepacia) produce endopolygalacturonase, whereas strains of clinical and soil origin do not.
Carlos F. Gonzalez, Elizabeth A. Pettit, Victoria A. Valadez, Ellen M. Provin   +3 more
doaj   +1 more source

Parasite variation and the evolution of virulence in a Daphnia-microparasite system [PDF]

, 2008
Understanding genetic relationships amongst the life-history traits of parasites is crucial for testing hypotheses on the evolution of virulence. This study therefore examined variation between parasite isolates (the bacterium Pasteuria ramosa) from the ...
Little, T. J., Chadwick, W., Watt, K.
core   +1 more source