Results 31 to 40 of about 205,054 (265)
Vibrio cholerae is an aquatic organism that causes the severe acute diarrheal disease cholera. The ability of V. cholerae to cause disease is dependent upon the production of two critical virulence determinants, cholera toxin (CT) and the toxin ...
X. Renee Bina +4 more
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Background and Objectives: Extraintestinal pathogenic Escherichia coli (ExPEC) is a recently recognized and highly diverse pathotype of E. coli. Its significance as a pathogen has increased due to the emergence of hypervirulent and multidrug-resistant ...
Alfredo Montes-Robledo +2 more
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Breaking the bad: Bacillus blocks fungal virulence factors
Fungal pathogens rely on the production of specific virulence factors during infection. Inhibiting such factors generally results in reduced fungal pathogenicity.
François L. Mayer, James W. Kronstad
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Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors
Summary: Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to ...
Diego López León +7 more
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Cauliflower mosaic virus (CaMV) transactivator/viroplasmin (Tav) is a multifunctional protein essential for basic replication of CaMV. It also plays a role in viral pathogenesis in crucifer and solanaceous host plants.
Kappei Kobayashi, Thomas Hohn
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The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that ...
Michiyo Okamoto +15 more
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Phytopathogenic strains of Burkholderia cepacia (synonym Pseudomonas cepacia) produce endopolygalacturonase, whereas strains of clinical and soil origin do not.
Carlos F. Gonzalez +3 more
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Virulence Factors in Coagulase-Negative Staphylococci [PDF]
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S. lugdunensis, the most clinically relevant species. Despite being less virulent than the well-studied pathogen S.
Angela França +3 more
openaire +4 more sources
Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage
The activity of fumagillin, a mycotoxin produced by Aspergillus fumigatus, has not been studied in depth. In this study, we used a commercial fumagillin on cultures of two cell types (A549 pneumocytes and RAW 264.7 macrophages).
Xabier Guruceaga +12 more
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Special Issue “Sporothrix and Sporotrichosis 2.0”
Sporotrichosis is a chronic fungal disease of humans and other mammals that often affects the skin and subcutaneous tissues and, rarely, deep-seated organs (most frequently in immunocompetent hosts) [...]
Héctor M. Mora-Montes
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