Molecular aspects of Bordetella pertussis pathogenesis [PDF]
The molecular mechanisms of Bordetella virulence are now well understood, and many virulence factors have been identified and characterized at the molecular level.
Camille Locht
core +2 more sources
A Single‐Molecule Liposome Assay for Membrane Permeabilisation
Cell membrane disruption is associated with numerous diseases and underlies the activity of various antimicrobial agents. The rapid screening of compounds capable of disrupting or permeabilising biological membranes is essential to the search for new therapeutic drugs.
Krzysztof Marek Bąk+9 more
wiley +1 more source
Factors Affecting Virulence of Shigella flexneri : Avirulent Strain with Altered Metabolism of Succinate, Fumarate, and Malate [PDF]
Rosalind Kim, Laurence M. Corwin
openalex +1 more source
An Approach for Molecular and Biological Characterizations of Virulent Influenza A Viruses [PDF]
We propose an approach based on a combination of physical, chemical, and mathematical methods to identify and characterize virulent influenza A viruses (IAVs) through the analysis of the hemagglutinin protein. These methods include the isoelectric point, extreme value theory, and tree-like classification. The characterization process involves molecular
arxiv
Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection [PDF]
Linda L. Blackwood+3 more
openalex +1 more source
pH‐Responsive AIE Photosensitizers for Enhanced Antibacterial Therapy
Bacterial infections significantly alter the local microenvironment, with acidic byproducts from bacterial metabolism leading to a pronounced pH reduction. Leveraging this characteristic, we synthesized and identified DHTPA, a near‐infrared (NIR) fluorescent and pH‐responsive aggregation‐induced emission (AIE) photosensitizer, for enhanced photodynamic
Qihang Ding+11 more
wiley +1 more source
Invasiveness of Aeromonas spp. in relation to biotype, virulence factors, and clinical features [PDF]
Ian M. Watson+3 more
openalex +1 more source
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah+4 more
wiley +1 more source
Altered Virulence of a Pleiotropic Staphylococcus aureus Mutant with a Low Producibility of Coagulase and Other Factors in Mice [PDF]
Keiko Seki+4 more
openalex +1 more source