Results 151 to 160 of about 171,270 (316)

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

open access: yesThe FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva   +5 more
wiley   +1 more source

Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy

open access: yesImmunology &Cell Biology, EarlyView.
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy   +10 more
wiley   +1 more source

Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring bla KPC and bla NDM: implications for public health threat mitigation

open access: yesAnnals of Clinical Microbiology and Antimicrobials
Background Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) co-producing bla KPC and bla NDM poses a serious threat to public health.
Qian Wang   +11 more
doaj   +1 more source

Covert dissemination of pLVPK-like virulence plasmid in ST29-K54 Klebsiella pneumoniae: emergence of low virulence phenotype strains. [PDF]

open access: yesFront Cell Infect Microbiol, 2023
Qiu J   +11 more
europepmc   +1 more source

Efficacy Assessment of Montanide GEL 02 PR and Liposome‐Based Encapsulation as Adjuvants for an FrpA Subunit Vaccine Against Photobacteriosis in Solea senegalensis

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Photobacteriosis is a major threat to marine aquaculture, and the siderophore transporter FrpA represents a promising target for effective subunit vaccine development. In this study, we evaluated Montanide GEL 02 PR and phosphatidylcholine‐based liposomes as aqueous and safer alternatives to Freund's adjuvant for an FrpA‐based subunit vaccine ...
Marta A. Lages   +7 more
wiley   +1 more source

Global Phylogeny and F Virulence Plasmid Carriage in Pandemic Escherichia coli ST1193. [PDF]

open access: yesMicrobiol Spectr, 2022
Wyrsch ER   +4 more
europepmc   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen   +4 more
wiley   +1 more source

De novo stolon organogenesis in potato leaf callus elicited by Agrobacterium tumefaciens stimulus

open access: yesJournal of Integrative Plant Biology, EarlyView.
Agrobacterium tumefaciens triggers stolon regeneration from potato leaf callus independent of T‐DNA insertion, suggesting a strategy to reprogram callus identity and expand the potential of tissue regeneration. ABSTRACT Plant cells can undergo cellular reprogramming, enabling pluripotent callus formation from excised leaves.
Seung Yong Shin   +7 more
wiley   +1 more source

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