Results 11 to 20 of about 2,401,730 (258)

The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion [PDF]

, 2014
The ability of Salmonella to cause disease depends on metabolic activities and virulence factors. Here, we show that a key metabolic protein, EIIAGlc, is absolutely essential for acute infection, but not for Salmonella survival, in a mouse typhoid fever ...
Timo Glatter, Dirk Bumann,, Glatter, Timo, Glatter, T. ; https://orcid.org/, Mazé, Alain, Bumann, Dirk, Timo Glatter,, Dirk Bumann, Alain Mazé, Maze, A., Alain Mazé,, Bumann, D.   +11 more
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The KdpD/KdpE two-component system : integrating K+ homeostasis and virulence [PDF]

, 2013
The two-component system (TCS) KdpD/KdpE, extensively studied for its regulatory role in potassium (K+) transport, has more recently been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria ...
Freeman, Zoë N., Zoë N Freeman, Steve Dorus, Waterfield, Nicholas R., Dorus, Steve, Nicholas R Waterfield   +5 more
core   +1 more source

Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence [PDF]

, 2014
Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through
Caly, Delphine L., Joseph Ward (645977), Yvonne McCarthy (109070), Melanie Febrer (185470), Murdoch, Sarah L., Dow, J. Maxwell, Joseph Ward, Robert P. Ryan (108478), Ryan, Robert P., An, Shi Qi, An Shi-qi, Ryan Robert P., Shi-qi An, Robert P Ryan, J. Maxwell Dow (269095), J Maxwell Dow, McCarthy Yvonne, Caly Delphine L., Dow J. Maxwell, An, Shi-qi, Ward Joseph, Delphine L Caly, Yvonne McCarthy, McCarthy, Yvonne, Sarah L Murdoch, Melanie Febrer, Sarah L. Murdoch (645976), Ward, Joseph, Shi-qi An (5661025), Febrer Melanie, Febrer, Melanie, Delphine L. Caly (146386), Murdoch Sarah L.   +32 more
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Effect of the zinc transporter ZupT on the virulence mechanisms of mesophilic Aeromonas salmonicida SRW‐OG1

Animal Research and One Health, 2023
As a typical psychrophilic bacterial pathogen, Aeromonas salmonicida causes furunculosis in wild and farmed freshwater and marine fish, leading to substantial economic losses in the global aquaculture industry.
Jiajia Wang, Qiu Li, Lixing Huang
doaj   +1 more source

ArcA positively regulates the expression of virulence genes and contributes to virulence of porcine Shiga toxin-producing enterotoxigenic Escherichia coli

Microbiology Spectrum, 2023
Enterotoxigenic Escherichia coli (ETEC) cause severe diarrhea in humans and animals. These bacteria encode two major classes of virulence factors, adhesins that promote colonization of the small intestine and enterotoxins that induce fluid secretion and ...
Fengwei Jiang, Yan Yang, Zhao Mao, Wentong Cai, Ganwu Li   +4 more
doaj   +1 more source

Role of glucose and CcpA in capsule expression and virulence of Streptococcus suis [PDF]

, 2011
Streptococcus suis is one of the most important pathogens in pigs and is also an emerging zoonotic agent. After crossing the epithelial barrier, S. suis causes bacteraemia, resulting in meningitis, endocarditis and bronchopneumonia.
Smith, H.E., Smith, H E, H. E. Smith, R. Goethe, Rohde, Manfred, Valentin-Weigand, P., M. Rohde, Goethe, R, J. Willenborg, Willenborg, J, de Greeff, A, Goethe, R., Willenborg, J., A. de Greeff, Valentin-Weigand, P, De Greeff, A., Greeff, A., De, P. Valentin-Weigand, Fulde, M., M. Fulde, Fulde, M, Rohde, M.   +21 more
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Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum [PDF]

, 2006
In many plant and animal bacterial pathogens, the Type III secretion system (TTSS) that directly translocates effector proteins into the eukaryotic host cells is essential for the development of disease.
Christian Boucher, Valls Marc, Valls i Matheu, Marc, Marc Valls, Boucher, Christian, Genin Stéphane, Genin, S., Boucher Christian, Stéphane Genin   +8 more
core   +2 more sources

Genomic Island-Encoded Histidine Kinase and Response Regulator Coordinate Mannose Utilization with Virulence in Enterohemorrhagic Escherichia coli

mBio, 2023
Enterohemorrhagic Escherichia coli (EHEC) is a highly adaptive pathogen and has acquired diverse genetic elements, such as genomic islands and prophages, via horizontal gene transfer to promote fitness in vivo.
Dawei Yang, Yongwu Yang, Pengfei Qiao, Fengwei Jiang, Xinyang Zhang, Zihui Zhao, Tao Cai, Ganwu Li, Wentong Cai   +8 more
doaj   +1 more source

Role of RelA and SpoT in Burkholderia pseudomallei Virulence and Immunity [PDF]

, 2012
Burkholderia pseudomallei is a Gram-negative soil bacterium and the causative agent of melioidosis, a disease of humans and animals. It is also listed as a category B bioterrorism threat agent by the U.S.
Wand, ME, Müller, CM, Conejero, L, Bancroft, Gregory J, Spink, N, Titball, Richard W., Titball, Richard W, Wand, Matthew E, Bancroft, Gregory J., Müller, Claudia M, Conejero, Laura, Spink, Natasha   +11 more
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Novel insights into the epigenetic regulation of Plasmodium falciparum virulence genes [PDF]

, 2013
Plasmodium falciparum malaria still places a major health burden upon the developing world. The high virulence of this parasite is linked to the variegated expression of single P.
Brancucci, Nicolas Michel Beat
core   +1 more source